Gene Information

Name : rph (TW640)
Accession : NP_789565.1
Strain : Tropheryma whipplei TW08/27
Genome accession: NC_004551
Putative virulence/resistance : Unknown
Product : ribonuclease PH
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0689
EC number : 2.7.7.56
Position : 727191 - 727961 bp
Length : 771 bp
Strand : -
Note : RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs

DNA sequence :
GTGTCTGTCACCTCGCTGGCGGTGTATATGCTGTTTTGTTGTATTATTTGCTCTGTGTTGAGGAAGAATTCTAGGGCACA
TGACGAAATTCGACCCGTAAAAATTATCCGCGGGTGGAATATTTATGCAGAGGGATCAGCCCTAATTGCTTTTGGCAATA
CCAGGGTTCTTTGTAATGCAACCTTTCAGCGCGGAGTTCCGCCGTTTTTACGCGGACAGAGATCTGGATGGATAACGGCA
GAATATGCTATGCTCCCGCGATCTGGTACCGAGCGATCTGACCGTGAATCTGTTAAGGGGAAAATTAGCGGTCGCAGTCA
TGAAATCAGTCGCCTCATAGGCCGAAGTATGCGTGCAATTTTGGATCGGTATGCTCTGGAGGAGAATACCATTATCCTAG
ATTGTGATGTCCTACAGGCCGACGGCGGGACGCGCACCGCCGCTATAACCGGTTCGTATATTGCGCTTTACGATGCCCTT
GTCTGGGCTAAAAATCAAAAGATACTTTCAAAGCATCCTCTGACTGATTCTGTATCCGCTGTGTCTGTTGGGCTAGTCGG
CGACCAGATTTTTCTAGACCTGGATTATTCGGAGGACTCAAATGCACAGGCTGACATTAATCTTGTTTTTACTGGAAGCG
GTAAATTAGTAGAGATTCAGGGTACTGCAGAAAAATCACCCTTTTCGTATGGACAGTTTGAGCAGATGATGGAACTTGCC
AAAACAGGTTGCCAAGCCCTAAAGGAGATACAGGCCGCTTCATTGGATTAA

Protein sequence :
MSVTSLAVYMLFCCIICSVLRKNSRAHDEIRPVKIIRGWNIYAEGSALIAFGNTRVLCNATFQRGVPPFLRGQRSGWITA
EYAMLPRSGTERSDRESVKGKISGRSHEISRLIGRSMRAILDRYALEENTIILDCDVLQADGGTRTAAITGSYIALYDAL
VWAKNQKILSKHPLTDSVSAVSVGLVGDQIFLDLDYSEDSNAQADINLVFTGSGKLVEIQGTAEKSPFSYGQFEQMMELA
KTGCQALKEIQAASLD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
rph YP_001800860.1 ribonuclease PH Not tested Not named Protein 3e-55 51