Gene Information

Name : smpB (TW571)
Accession : NP_789499.1
Strain : Tropheryma whipplei TW08/27
Genome accession: NC_004551
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 623081 - 623716 bp
Length : 636 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
GTGCACAGGCGATCTTCTAAGAGTTACTCTTCCAGGAATTCTAAAACTCCAGAGCGTTCTAAAATTCCAGATTGCGTTAT
CGCATCAAACAAAAGCGCAGAATATAACTATTTTCTGGACAAAACATTTGAGGCAGGCCTTGTCCTACTGGGCAGTGAGG
TAAAAAGCGTCAGACAGCAAAAAATAAGTCTGTCTGAGGCCTATATTTATGAGGATAACTCAGAAATATGGCTTGCCAAT
CTGTATATCCCAGAGCACAAAACGGGGGGATGGACCAATCATAACCCCCGGCGACTCAGAAAACTATTGTTACACAAGTA
CCAAATTGCACGTCTACGAAAAGATCTATTAATCCCTGGTATAACCCTGGTGCCCATCAAGTTTTATTTCAGGAACGGCC
GCGCGAAGCTTCTTATATCCCTTGCGCGAGGTAAAAAGCTAATTGACAAGCGCGAGGTAATAAAAGAGCGAGAGGCCACT
CTAGAAGCAAACCGTGCCCTAAAACATCGCTTACGCAGACCCCGTGCACAGCGCAATACACAACGCAGTGTAACACCGCG
CAGCACGCGGGAAAATAAAAATGTACAGAGAAATAAGGCAAGGTCTGCCAGGTGCAATGTACGGCATGAAAACTAA

Protein sequence :
MHRRSSKSYSSRNSKTPERSKIPDCVIASNKSAEYNYFLDKTFEAGLVLLGSEVKSVRQQKISLSEAYIYEDNSEIWLAN
LYIPEHKTGGWTNHNPRRLRKLLLHKYQIARLRKDLLIPGITLVPIKFYFRNGRAKLLISLARGKKLIDKREVIKEREAT
LEANRALKHRLRRPRAQRNTQRSVTPRSTRENKNVQRNKARSARCNVRHEN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 3e-24 46