Gene Information

Name : glnA (TW509)
Accession : NP_789438.1
Strain : Tropheryma whipplei TW08/27
Genome accession: NC_004551
Putative virulence/resistance : Virulence
Product : glutamine synthetase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0174
EC number : 6.3.1.2
Position : 547499 - 548923 bp
Length : 1425 bp
Strand : +
Note : Similar to Escherichia coli glutamine synthetase GlnA or b3870 or z5406 or ecs4792 SWALL:GLNA_ECOLI (SWALL:P06711) (468 aa) fasta scores: E(): 2.2e-89, 48.62% id in 471 aa

DNA sequence :
GTGTTTGAAAATGCAAAAGAGGCAGCTGAGTATATAAAATCGAATCAAATTGAAGTGCTTGATGTTCGCTTCTGTGATTT
TCTCGGCGCTCAACATCATTTTGCCGTCCCTGCTCACGCAGTGGATGATGAGTTTTTTCAGTCACCCCAGGTCTTTGATG
CTTCCTCTCTGAGGGGCTATGCGGATATAAACCATTCAGATATGCTTCTTGTCGCAGATCCATCGACGTCCTATATTGAC
CCGTTTAGACACCACAAAACCCTTGCGATGATCTTTGATGTGCACGATCCACGCACGGGGGACGTTTATGAGCGCGACTC
ACGTAATGTGGCTAAAAAGGCAGAAAAGTACCTCGCGGGGTGCCGTTTTGCAGATACAGCGTATTTCGCAGCCGAAGCTG
AGTTTTTCATCTTTGATGACGTTCGGTTCAAGATCAGCAATCACTCATCATCCTATTCTGTTGATTCAGAGGAAGGTATT
TGGAACTCATCACGCAGGAAAGGGGGTGGGAACCTTGGTAATCAGCTCAAACACAAGGGAGGATACGCCCCCCTTCCCCC
TGCGGATCAACACGCCGACCTGCGCGATGACATAATGAATGCCCTAACAAAGGTTGGTCTGCGTGTTGAAAAAGGTCATC
ATGAAGCTGGCTCCGCGGGTCAAGGTGAGATAAATTACAGATTTAACACACTCGTCAATGCAGCAGATGATTTGCTGAAA
TTCAAATATGTCGTCAAAAACACAGCACATGAATGGGGAAAAAGCGCTACCTTTATGCCAAAGCCAATTGCCGGAGACAA
TGGGTCCGGGATGCACACTCATCAGTCACTGTGGAAAAATGGAAAACCCCTGTTCTACAGTGAAACCGGGTATGCCAATT
TGAGCGATATCGCCCTGTGGTACATAGGTGGCCTGCTAAAACATGGCCCTGCTCTAGCAGCATTTACGAACCCGTCAACG
AACTCATACAAGAGACTTGTTGCCGGATTTGAAGCACCAACCAGTCTCGTTTACTCTGCGGGCAACCGTTCGGCTGCTAT
CAGGATCCCCCCAACAATCGGAGCTGAAGGCAGTAAAAGAATTGAATACAGAGTGCCGGACTCCTCTTCAAATCCATATC
TCGCGTTTTCTGCCTTGCTTATGGCAGGAATAGACGGAATAAAGAATAAAATACACCCGGGCAGCCCGGTTGAGCAGAAT
ATGTACGAGCTCACAAAGGAGCAGTCAAGGGACCTGCGATATCTACCAAGCTCACTCAGCGATGCACTGCGTGCTCTTGA
GCAAGACTGTGATTTCCTCCTTGAGGGGAATGTATTCACCCGTGAATTCATTAGCGCATGGATTGATTACAAGAGGAAGA
ATGAGCTTAACCGGATTGCGCAGTATCCTCATCCACTTGAATTTGGGATGTATTATGGGGTGTGA

Protein sequence :
MFENAKEAAEYIKSNQIEVLDVRFCDFLGAQHHFAVPAHAVDDEFFQSPQVFDASSLRGYADINHSDMLLVADPSTSYID
PFRHHKTLAMIFDVHDPRTGDVYERDSRNVAKKAEKYLAGCRFADTAYFAAEAEFFIFDDVRFKISNHSSSYSVDSEEGI
WNSSRRKGGGNLGNQLKHKGGYAPLPPADQHADLRDDIMNALTKVGLRVEKGHHEAGSAGQGEINYRFNTLVNAADDLLK
FKYVVKNTAHEWGKSATFMPKPIAGDNGSGMHTHQSLWKNGKPLFYSETGYANLSDIALWYIGGLLKHGPALAAFTNPST
NSYKRLVAGFEAPTSLVYSAGNRSAAIRIPPTIGAEGSKRIEYRVPDSSSNPYLAFSALLMAGIDGIKNKIHPGSPVEQN
MYELTKEQSRDLRYLPSSLSDALRALEQDCDFLLEGNVFTREFISAWIDYKRKNELNRIAQYPHPLEFGMYYGV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
glnA YP_003728749.1 glutamine synthetase Not tested cag PAI Protein 4e-80 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
glnA NP_789438.1 glutamine synthetase VFG1399 Protein 1e-114 56