Gene Information

Name : metB (ECA4252)
Accession : YP_052339.1
Strain : Pectobacterium atrosepticum SCRI1043
Genome accession: NC_004547
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 4765731 - 4766891 bp
Length : 1161 bp
Strand : -
Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine

DNA sequence :
ATGACGCGTAAACAGGCAACGATCGCAGTCCGCAGCGGGTTAAATGATGATGAACAGTATGGCTGCGTCGTCCCCCCTAT
TCACCTTTCCAGCACGTATAACTTTACCGGATTCAACCAGCCACGCGCACACGACTATTCGCGTCGCGGTAATCCCACAC
GTGATGTGGTACAGCGTGCGCTTGCCGAACTGGAAGGCGGTGCGGGTGCGGTAATGACGAGCAGCGGGATGTCGGCGATT
ATGCTGGTTTGCACGGTGTTCCTACGTCCCGGCGATCTGCTGGTGGCTCCGCATGACTGCTACGGTGGCAGCTATCGTCT
GTTTGACAGCCTGAGCAAGCGCGGCGCGTTTCGCGTCAAATTTGTCGATCAAGGTGATACCCATGCGCTCAACGCGGCGT
TGGCAGAAAAGCCGAAGCTCGTGCTGGTGGAAAGCCCGAGCAATCCGCTGCTGCGTGTCGTCGATATTGCTGCGATTTGT
CAGGCTGCGCGGGAAGCCGGTGCGGTCAGCGTGGTGGATAACACTTTCCTGAGCCCCGCGTTGCAGAAGCCGCTGGAACT
GGGAGCCGATCTGGTGGTGCATTCGTGTACCAAGTACCTGAATGGTCACTCTGACGTGGTGGCGGGTGCAGTGATCGCCA
AGGATGTCGATACCATCACTGAACTAGCTTGGTGGGCAAACAATATTGGTGTGACGGGGGCGGCGTTTGACAGTTATCTG
CTGCTACGTGGCCTGCGTACCTTATCGCCGCGCATGGCGGCCGCGCAGCGTAATGCGCAACAAGTGGTTGAATTCTTACA
GACGCAGCCGCTAGTGAAAGCTCTGTATCATCCTTCACTGCCGAACAATCCCGGCCATGATATTGCCCGTCGTCAACAAT
CTGGTTTTGGCGCTATGCTAAGTTTTGAGCTGGATGGAGATGAAGACACCCTGCGACGTTTTCTGGCCTCGCTGGAGCTG
TTCACGCTGGCGGAATCGCTGGGCGGGGTTGAGAGCCTCATCTCTCATGCTGCAACGATGACGCATGCGGGTATGGCGCC
AGAGGCGCGTGCCGCAGCGGGTATCTCTGAAACATTACTGCGTATTTCCACCGGCATTGAAGACGGCGATGATCTGGTTG
CCGATCTGGATCGTGCGTTTCAAGCCGCAGCCAAGAGGTAA

Protein sequence :
MTRKQATIAVRSGLNDDEQYGCVVPPIHLSSTYNFTGFNQPRAHDYSRRGNPTRDVVQRALAELEGGAGAVMTSSGMSAI
MLVCTVFLRPGDLLVAPHDCYGGSYRLFDSLSKRGAFRVKFVDQGDTHALNAALAEKPKLVLVESPSNPLLRVVDIAAIC
QAAREAGAVSVVDNTFLSPALQKPLELGADLVVHSCTKYLNGHSDVVAGAVIAKDVDTITELAWWANNIGVTGAAFDSYL
LLRGLRTLSPRMAAAQRNAQQVVEFLQTQPLVKALYHPSLPNNPGHDIARRQQSGFGAMLSFELDGDEDTLRRFLASLEL
FTLAESLGGVESLISHAATMTHAGMAPEARAAAGISETLLRISTGIEDGDDLVADLDRAFQAAAKR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-57 42
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-59 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_052339.1 cystathionine gamma-synthase BAC0207 Protein 9e-50 42