Gene Information

Name : murD (ECA3817)
Accession : YP_051906.1
Strain : Pectobacterium atrosepticum SCRI1043
Genome accession: NC_004547
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 4265910 - 4267226 bp
Length : 1317 bp
Strand : -
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGGTGGACTATCAGGGTAAAAAAGTCGTCATTATCGGGTTGGGTCTGACCGGGCTCTCCTGTGTTGATTTCTTTCTCGC
GCGTGGTGTCGTACCGCGCGTGGTGGATACCCGTATCAGTCCACCGGGTCTGGATAAGCTGCCGGAGCAGGTAGAACGAC
ATCTCGGTAGCCTGAATGAAGACTGGCTGATGAGCGCGGATTTGATCGTCGCCAGCCCCGGTGTTGCGTTGGCGACGCCG
ATTCTGTGTGACGCCGCTGACGCTGGCATTGAAATTGTTGGTGATATCGAACTGTTCTGCCGTGAAGCGCAGGCACCGAT
TGTGGCGATTACCGGATCTAACGGTAAAAGCACGGTGACGACACTGGTCGGTGAAATGGCGCGTGCCGCAGGCTGGCAGG
TTGGCGTCGGTGGCAATATTGGCCTACCTGCGCTGCAATTGCTGGAACATCCCGCTCAGCTGTATGTACTAGAGTTGTCG
AGCTTCCAACTGGAAACGACGACTAGCCTGCACGCTGCTGCGGCAACGATTCTGAACGTGACGGAAGATCACACTAACCG
TTACCCGTTTGGTTTACAGCAGTATCGGGCGGCGAAATTGCATATTTATGAACACGCAGATTTGTGTGTTGTGAATGCTG
ACGATGCGCTGACCATGCCGGTTCGCGGGGCGGATGCGCGCTGCCGCAGTTTTGGCGTTGATGTTGGCGATTATCACCTT
AACCGCCAGCAGGGCGAAACCTGGCTGCGGGTGGACGGTGAACGTGTGCTCAACACCCGTGAAATCAAGCTTGTCGGGCA
GCACAATTATACGAACGCATTGGCGGCGCTGGCGCTGGCTGATGCTGTGAAGATTCCACGCGCGTCTGCGCTGACGGCGT
TGACGTCATTTACCGGGCTGCCGCACCGTTTTCAAATGGCCTTTGAGCGCAATGGCGTGCGGTGGATCAATGATTCCAAA
GCCACCAATGTAGGCAGCACCGAAGCCGCATTGAGCGGTTTGGCTGTAGACGGCACTTTGCATCTGCTATTAGGTGGTGA
CGGGAAATCTGCTGATTTCTCGCCATTGGTGCCGTATTTACAGGGTGAGCGCATTCGTTTGTATTGCTTTGGTCGTGACG
GGCAACAGTTGGCAGCGTTACGCCCAGAAATTGCCGAGCAGACAGAAACGATGGAACAGGCGATGCGCGTTATTGCTGAA
CGTATAAGGCCGGGCGATATGGTGTTGCTGTCGCCGGCTTGCGCTAGCTTGGATCAGTTTCGCAGTTTTGAACAGCGAGG
CGATGAGTTTGCTCGTCTGGCGGAGGAGCTAGGCTAA

Protein sequence :
MVDYQGKKVVIIGLGLTGLSCVDFFLARGVVPRVVDTRISPPGLDKLPEQVERHLGSLNEDWLMSADLIVASPGVALATP
ILCDAADAGIEIVGDIELFCREAQAPIVAITGSNGKSTVTTLVGEMARAAGWQVGVGGNIGLPALQLLEHPAQLYVLELS
SFQLETTTSLHAAAATILNVTEDHTNRYPFGLQQYRAAKLHIYEHADLCVVNADDALTMPVRGADARCRSFGVDVGDYHL
NRQQGETWLRVDGERVLNTREIKLVGQHNYTNALAALALADAVKIPRASALTALTSFTGLPHRFQMAFERNGVRWINDSK
ATNVGSTEAALSGLAVDGTLHLLLGGDGKSADFSPLVPYLQGERIRLYCFGRDGQQLAALRPEIAEQTETMEQAMRVIAE
RIRPGDMVLLSPACASLDQFRSFEQRGDEFARLAEELG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 6e-57 41
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 6e-57 41