Gene Information

Name : guaA (ECA3208)
Accession : YP_051297.1
Strain : Pectobacterium atrosepticum SCRI1043
Genome accession: NC_004547
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 3589055 - 3590632 bp
Length : 1578 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACTCAAAACATTCATCAACACCGCATTCTTATTCTGGATTTCGGCTCGCAGTACACGCAGCTGGTTGCACGTCGCGT
GCGTGAGCTGGGCGTTTACTGTGAACTGTGGGCATGGGATGTCACGGAAGCGCAGATTCGCGGCTTTAATCCGAACGGGA
TCATCCTGTCTGGTGGCCCGGAAAGCACCACCGAGTTTGGCAGCCCGCGTGCGCCAGAATACGTTTTCAACGCTGGCGTA
CCGGTATTAGGCGTGTGCTATGGCATGCAGACGATGGCGATGCAGCTGGGTGGCCACGTTGAAGGTTCCAACGAGCGTGA
GTTTGGTTATGCGCAGGTAGAAGTTAAAACTAATAGCGCGCTGGTGCGTGATATTCAGGATGCGTTGAGCGCCACGGGCG
CGCCGCTGCTGGATGTCTGGATGAGCCACGGCGACAAAGTAACGGCGATCCCAGAAGGGTTCGAGACCGTTGCCAGTACG
GATACCTGTCCGTTCGCTATCATGGCTAACGAAGAGAAACGTTTTTACGGCGTGCAGTTCCACCCGGAAGTGACGCACAC
GCGTCAGGGCCAGCGCATGTTAGAGCGTTTTGTCCTTGATATCTGCCAGTGTGAAGCTCTGTGGACACCAGCCAAGATTA
TCGACGATGCGGTGAACCGTATTCGCGAGCAGGTGGGTAACGACAGCGTGATTTTGGGTCTGTCTGGCGGCGTGGATTCT
TCCGTTACCGCGATGCTGCTGCACCGTGCGATTGGTGACCGCCTGACCTGCGTGTTTGTCGACAACGGCCTGCTTCGCCT
GAACGAAGCCGATCAGGTTCTGGAAATGTTCGGCGATAATTTTGGTCTGAACATTGTTCATGTGGCGGCAGAAGATCGCT
TCCTGAACGAGCTGGCGGGTGAAGATGAGCCAGAAGCCAAGCGTAAAATCATTGGCCGCGTGTTTGTTGAAGTGTTCGAT
GAAGAAGCCAACAAGCAAGCCGAAGTGAAATGGCTGGCTCAAGGCACCATCTACCCGGACGTGATCGAATCTGCGGCGTC
TGCGACGGGCAAAGCGCACGTGATCAAGTCACACCACAACGTGGGTGGCCTGCCGAAAGAGATGAAGCTGGGTCTGGTCG
AGCCGTTGAAAGAGCTGTTCAAAGATGAAGTGCGCAAGATTGGTCTGGAACTGGGTCTGCCGTACAACATGCTGTACCGC
CATCCGTTCCCTGGCCCAGGCCTGGGCGTGCGTGTACTGGGTGAAGTGAAGAAAGAATACTGTGACCTGCTGCGTCGTGC
GGATGCGATCTTCATCGAAGAACTGCACAAAGCTGACCTGTATAACAAGGTTAGCCAAGCATTCACCGTCTTCCTGCCGG
TCCGGTCCGTAGGCGTAATGGGTGATGGCCGTAAATACGATTGGGTTGTCGCGCTGCGCGCAGTAGAAACCATCGACTTT
ATGACTGCGCACTGGGCACACTTGCCATACGATTTCCTCGGCCGTGTATCCAACCGCATCATCAACGAAGTCGACGGCAT
CTCCCGCGTCGTTTACGACGTATCGGGCAAGCCGCCGGCAACGATTGAGTGGGAATGA

Protein sequence :
MTQNIHQHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIRGFNPNGIILSGGPESTTEFGSPRAPEYVFNAGV
PVLGVCYGMQTMAMQLGGHVEGSNEREFGYAQVEVKTNSALVRDIQDALSATGAPLLDVWMSHGDKVTAIPEGFETVAST
DTCPFAIMANEEKRFYGVQFHPEVTHTRQGQRMLERFVLDICQCEALWTPAKIIDDAVNRIREQVGNDSVILGLSGGVDS
SVTAMLLHRAIGDRLTCVFVDNGLLRLNEADQVLEMFGDNFGLNIVHVAAEDRFLNELAGEDEPEAKRKIIGRVFVEVFD
EEANKQAEVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKLGLVEPLKELFKDEVRKIGLELGLPYNMLYR
HPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVALRAVETIDF
MTAHWAHLPYDFLGRVSNRIINEVDGISRVVYDVSGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-129 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-129 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-129 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 7e-112 48