Gene Information

Name : tpx (ECA1990)
Accession : YP_050084.1
Strain : Pectobacterium atrosepticum SCRI1043
Genome accession: NC_004547
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : 1.11.1.-
Position : 2258122 - 2258625 bp
Length : 504 bp
Strand : -
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein

DNA sequence : 
ATGTCACAGAACGTACATTTTCAAGGCAATCCTGTGCCAGTAGCTGGGTCATTCCCGGCCAAAGGAAGCAAAGCGCCAGC
ATTCACTATGGTCGCTAAAGACCTGTCAGATGCTTCACTCAGCAACTATGCTGGCAAGCGCAAAATCCTGAACATTTTCC
CAAGCATCGATACCGGTGTTTGTGCCGCGTCCGTGCGTAAATTTAACCAGTTGGGTTCTGAGCTGGATAACACCGTTGTT
CTGTGTATCTCTTCCGATCTGCCGTTTGCACAGTCCCGTTTTTGCGGTGCGGAAGGTCTGAACAACGTGGTTGTACTGTC
TACCCTGCGTGGCGGTGAGTTCAAAGAAAGCTACGGCGTTGCTATTGCAGATGGTGCGCTGAAAGGCCTGACCGCTCGTG
CTGTCGTGGTGCTGGACGAAAATGACAACGTTCTGCATAGCGAACTGGTGAATGAAATCACCACTGAACCAGACTATGAC
GCTGCACTGGCTGTTTTGAAATAA

Protein sequence : 
MSQNVHFQGNPVPVAGSFPAKGSKAPAFTMVAKDLSDASLSNYAGKRKILNIFPSIDTGVCAASVRKFNQLGSELDNTVV
LCISSDLPFAQSRFCGAEGLNNVVVLSTLRGGEFKESYGVAIADGALKGLTARAVVVLDENDNVLHSELVNEITTEPDYD
AALAVLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 3e-36 50
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 1e-35 50
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 5e-36 50
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 7e-36 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_050084.1 thiol peroxidase VFG0087 Protein 1e-36 50