Gene Information

Name : intB (ECA1679)
Accession : YP_049780.1
Strain : Pectobacterium atrosepticum SCRI1043
Genome accession: NC_004547
Putative virulence/resistance : Unknown
Product : phage integrase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0582
EC number : -
Position : 1925682 - 1926959 bp
Length : 1278 bp
Strand : -
Note : Similar to Yersinia pestis integrase IntB or ypo3438 SWALL:Q8ZBH6 (EMBL:AJ414157) (419 aa) fasta scores: E(): 2.4e-97, 58.15% id in 423 aa, and to Shigella flexneri integrase IntB or sf4224 SWALL:AAN45643 (EMBL:AE015430) (415 aa) fasta scores: E(): 2.4e-9

DNA sequence :
ATGTCTCTAACTGATTCCAAAGTAAAAAATGCCAAATCTCTTGAGAAGGAATATAAGCTTACTGATGGCTTTGGTATGCA
CCTGCTAGTGCATCCTAATGGATCTAAATACTGGCGCTTGTCTTATCGTTTCGAAAAGAAGCAAAGATTACTCGCTTTAG
GCGTCTATCCTGCTGTTTCTTTGGCTGATGCCAGACAACGCCGGGATGAAGCGAAAAAGCTGTTAGCTGCTGGTATTGAC
CCCAGCGCTAAAAAGCAGGCTGACAACAAAACCATTCAAGAGAAGCGTAACAATACCCGCGCTTTCAAAACCGTCGCCAA
AAGCTGGTTTTCCACCAAAACCACATGGTCGGAAGATTATCAGCGTTCTGTCTGGACACGACTGGAAACTTATCTGTTCC
CTGATATTGGCAACAAAGATATTGCTGAACTGGATACAGGCGATCTGCTGGCTCCCATCAAAAAGATAGAGAAGCTGGGT
TATCTGGAAATCGCCATGCGGGTGAAACAGTACACGACCGCCATCATGCGTTATGCCGTCCAGCAAAAGATGATCCGTTT
CAATCCAGCCTATGATTTGGAAGGTGCGGTTCAGAAGCCTCAGACGGAACACCGCCCCGCTATCGAGCTTGAAGAGATCC
CTACCCTACTGGAACGTATTGAAGGCTATCAGGGGCGTAGCAGACTGACCCAATTGGCGATAAAACTCAATTTGCTGATT
TTTGTGCGTTCCAGTGAACTCCGCTTTGCCCGTTGGTCAGAGATCGATTTCAAAAGTGCTTTATGGGTTATCCCTGAACA
ACGTCAAGCCATTGAAGGGATAAAGCATTCAGGTCGGGGTGCCAAAATGCGCAGGAAACATTATGTTCCTCTATGCGATC
AAGCACTGGCAATTTTGGAAGAGCTTAAAGACCTCACCTATGACGTTAACGGTGATGACGGCTTTATCCTGACTGGCTGT
TATGATGCGATGAAGCCGATGAGTGAAAACACCATCAACAAGGCGCTTCGTAAAATGGGCTATGACACCAAAACCGATCT
GTGCGGCCACGGCTTTCGAACGCTGGCGTGTAGTGCATTAATTGAATCAGGTATCTGGCCGGAAGACGTGGTTGAACTTC
AGATGAGCCACATGGAAAAGAACAACGTTCGTGCTGCCTACACTCACAAGGCCAAACACCTTGAGCAACGCCGCCTGATG
TTGCAATGGTGGGCTGATTTTCTTGATGCTAACCGCAACGGGATGGTTAGGCCGTTTGAATTTGCGCAGAAGGGATAA

Protein sequence :
MSLTDSKVKNAKSLEKEYKLTDGFGMHLLVHPNGSKYWRLSYRFEKKQRLLALGVYPAVSLADARQRRDEAKKLLAAGID
PSAKKQADNKTIQEKRNNTRAFKTVAKSWFSTKTTWSEDYQRSVWTRLETYLFPDIGNKDIAELDTGDLLAPIKKIEKLG
YLEIAMRVKQYTTAIMRYAVQQKMIRFNPAYDLEGAVQKPQTEHRPAIELEEIPTLLERIEGYQGRSRLTQLAIKLNLLI
FVRSSELRFARWSEIDFKSALWVIPEQRQAIEGIKHSGRGAKMRRKHYVPLCDQALAILEELKDLTYDVNGDDGFILTGC
YDAMKPMSENTINKALRKMGYDTKTDLCGHGFRTLACSALIESGIWPEDVVELQMSHMEKNNVRAAYTHKAKHLEQRRLM
LQWWADFLDANRNGMVRPFEFAQKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
intB CAD42017.1 bacteriophage P4 integrase Not tested PAI II 536 Protein 8e-118 61
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 7e-115 56
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 6e-115 56
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 3e-115 56
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 1e-109 56
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 1e-109 56
int-phe AAL60261.1 Int-phe Not tested LEE Protein 3e-115 56
ECO103_3550 YP_003223418.1 integrase Not tested LEE Protein 4e-115 56
ECO26_5300 YP_003232178.1 integrase Not tested LEE Protein 4e-115 56
int AAK16198.1 Int Not tested PAI-I AL862 Protein 3e-115 56
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 3e-115 56
int-phe AAL57571.1 CP4-like integrase Not tested LEE Protein 3e-115 56
int AAL51028.1 CP4-like integrase Not tested LEE Protein 3e-115 56
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 2e-113 55
int AAK00456.1 Int Not tested SHI-1 Protein 7e-107 55
S4822 NP_838459.1 P4-type integrase Not tested SHI-1 Protein 4e-115 55
SF2964 NP_708738.1 P4-type integrase Not tested SHI-1 Protein 4e-115 55
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 3e-114 55
int AAL51003.1 CP4-like integrase Not tested LEE Protein 2e-114 55
intP4 CAE85151.1 CP4 integrase protein Not tested PAI V 536 Protein 5e-115 55
int CAC81896.1 integrase Not tested LEE II Protein 1e-106 55
ECUMN_3322 YP_002414004.1 integrase Not tested Not named Protein 2e-113 55
Z4313 NP_289539.1 pathogenicity island integrase Not tested OI-122 Protein 2e-114 55
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 2e-114 55
int NP_458759.1 bacteriophage integrase Not tested SPI-7 Protein 1e-103 52
int NP_807963.1 bacteriophage integrase Not tested SPI-7 Protein 1e-103 52
STY4821 NP_458899.1 integrase Not tested SPI-10 Protein 3e-98 50
unnamed ABR13507.1 phage integrase Not tested PAGI-6 Protein 4e-96 49
APECO1_1051 YP_853069.1 phage integrase Not tested PAI IV APEC-O1 Protein 8e-67 48
intB AAD37509.1 P4-like integrase Not tested PAI IV 536 Protein 3e-79 48
int CAA21384.1 - Not tested HPI Protein 6e-94 48
int CAA08754.1 integrase Not tested HPI Protein 2e-94 48
int CAB59974.1 integrase Not tested HPI Protein 1e-94 48
int YP_002346908.1 integrase Not tested HPI Protein 6e-94 48
y2393 NP_669700.1 prophage integrase Not tested HPI Protein 6e-94 48
int2 NP_993013.1 integrase Not tested HPI Protein 6e-94 48
unnamed AAD17660.1 unknown Not tested HPI Protein 2e-90 47
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 2e-72 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
intB YP_049780.1 phage integrase VFG1536 Protein 4e-118 61
intB YP_049780.1 phage integrase VFG0626 Protein 2e-115 55
intB YP_049780.1 phage integrase VFG1693 Protein 7e-115 55