Gene Information

Name : thyA (bbp386)
Accession : NP_777993.1
Strain : Buchnera aphidicola Bp (Baizongia pistaciae)
Genome accession: NC_004545
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 445638 - 446432 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAGAGTTATTTGGTTTTGTTAAAAAAAATATTAAAAGAAGGAAGTAATAGGAAAGATCGAACAGGAATAGGAACATT
ATCAGTTTTTGGATATCATATGGAATTTAATTTGAAATTGGGATTTCCGTTAATTACGACTAAAAAATGTCATTTTCCTG
CTATAGTTCATGAACTTTTGTGGTTTTTAAAGGGAGATACAAATATAAAGTATTTAAATGATCATAATATATCTATTTGG
AATCCATGGGCTGATGAACGTGGATATTTAGGTCCAATTTATGGAGAACAATGGAGATCATGGAAAACAAAAGATGGACG
TGTAATTGATCAAATAGATAATGTAATACATTTAATAAAAAACAATCCAAATTCTCGAAGAATAGTTGTATCTAGTTGGA
ATGTTGGTGATTTACATAAAATGGCATTATTACCATGTCATGTATTATTTCAGTTTCACGTTGTTGATCACGTTTTGCAT
TGTCAATTATATCAGCGATCTTGTGATGTTTTTCTTGGTTTGCCTTTTAATATAGCTAGTTATTCTTTATTAACACATAT
GATAGCACAACAGTGTAATCTAAAAGTAGGTAATTTTATATGGACTGGCGGTGATGTGCATTTATATAAAAATCATATCA
AACAAGCTAAAAAACAAATTTTAAGACGTCCTTATTTACTTCCAAAATTAGTTATTAACAGAAAACCTACTCAAATATTT
AATTATCTTTTACAAGATTTTAATTTATTGAATTATAAATATCATCCTTCTATTCATGCTAAAATAGCAATATAA

Protein sequence :
MKSYLVLLKKILKEGSNRKDRTGIGTLSVFGYHMEFNLKLGFPLITTKKCHFPAIVHELLWFLKGDTNIKYLNDHNISIW
NPWADERGYLGPIYGEQWRSWKTKDGRVIDQIDNVIHLIKNNPNSRRIVVSSWNVGDLHKMALLPCHVLFQFHVVDHVLH
CQLYQRSCDVFLGLPFNIASYSLLTHMIAQQCNLKVGNFIWTGGDVHLYKNHIKQAKKQILRRPYLLPKLVINRKPTQIF
NYLLQDFNLLNYKYHPSIHAKIAI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 1e-71 58
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 3e-52 43