Gene Information

Name : serS (bbp290)
Accession : NP_777910.1
Strain : Buchnera aphidicola Bp (Baizongia pistaciae)
Genome accession: NC_004545
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 339256 - 340554 bp
Length : 1299 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTAAATCCTAATTTGTTACGCAACCATATAGAGTTTGTTTTTAAAAACTTAGCTAGACGCGGGTTTTCGTTAGATGT
AAAACAATTTACTGAAATGGAAAAAAAACGAAAAATTTTACAAACTAAAGTAGAAGAGCTTCAATCAAGACATAACACTT
TATCTAAACATATTGGAAGAATAAAACTTATACATCCAAATATTCAATGTATGAAAGAAAGAATAATAACATTAAAAAAA
AAAATAGACGTTATGAAAAAAGAACTCAAAATTTTATTAGAACAAATTCATATTTTTTTAATGAATATTCCTAATCTTCC
AGATATTAACATTCCTGATGGAATGGGTTCAGATGATAATCAAGAAGTTAGTCGTTGGGGAATTATAAAAAATTATAATT
TTAAAATTAAAAACCATGTTGAATTAGGAAATCATCTCAATGGTTTTGATTGGAAATCTGCAGCTAATATTTCTGGATCT
AGATTTTTCATTATGAAAGGAAAAATAGCTCTTTTATATCGAGTTTTAGGACAATTTATGTTAGATTTGCATACTAATGA
ACATGGATATCTAGAAACATATGTTCCATGTTTAGTTAAAACAAATAATTTATATGGTACAGGTCAATTACCTAGATTTA
AAACGGATTTATTTTACGCTAAATCACTTTTAGATGAATCACAAAATAATAATAATTTTGCATTAATACCGACTGCTGAA
GTTCCGTTAACTAATTTGTTTCGTGATTGTATATTAGATGAACAACAATTACCAATTATGTTAGTTGCTAAAACACCTTG
CTTTCGTTCAGAAGCTCTGTCTTACGGACGAGATACACAAGGTTTAATTCGTACGCATCAATTTGATAAAGTAGAGATTG
TTCAGATTGTACATCCAAGTGATTCTATGCAGAAATTGGAAGAATTAACAATACATGCTGAAAGAGTTTTGAAATTATTA
AAATTACCATATCGAAAAACGTTATTATGTACACGAGATATAGGATTTTCGTCTTCTAAAACCTATGATTTAGAAGTGTG
GTTTCCTTCTCAAAATGTTTATCGAGAAGTATCTTCTTGTTCCAACATGTTAGATTTTCAAGCTCGAAGAATAAAAGCAA
GATTTCATTGTAACGCACAAAATAAAAAAATTTTTATACATACTATTAATGGATCTGGATTAGCTGTTGGAAGAACTTTA
GCAGCAATTTTAGAAAATTATCAGCAAAAAGACGGGAGAATTAAAATACCTAAAATATTAAGAAATAACTACATGAATGG
ATTAGAATTTTTAGAATAG

Protein sequence :
MLNPNLLRNHIEFVFKNLARRGFSLDVKQFTEMEKKRKILQTKVEELQSRHNTLSKHIGRIKLIHPNIQCMKERIITLKK
KIDVMKKELKILLEQIHIFLMNIPNLPDINIPDGMGSDDNQEVSRWGIIKNYNFKIKNHVELGNHLNGFDWKSAANISGS
RFFIMKGKIALLYRVLGQFMLDLHTNEHGYLETYVPCLVKTNNLYGTGQLPRFKTDLFYAKSLLDESQNNNNFALIPTAE
VPLTNLFRDCILDEQQLPIMLVAKTPCFRSEALSYGRDTQGLIRTHQFDKVEIVQIVHPSDSMQKLEELTIHAERVLKLL
KLPYRKTLLCTRDIGFSSSKTYDLEVWFPSQNVYREVSSCSNMLDFQARRIKARFHCNAQNKKIFIHTINGSGLAVGRTL
AAILENYQQKDGRIKIPKILRNNYMNGLEFLE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 9e-87 46