Gene Information

Name : SE0086 (SE0086)
Accession : NP_763641.1
Strain : Staphylococcus epidermidis ATCC 12228
Genome accession: NC_004461
Putative virulence/resistance : Resistance
Product : alkylmercury lyase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 86993 - 87643 bp
Length : 651 bp
Strand : +
Note : cleaves the carbon-mercury bond of organomercuric compounds

DNA sequence : 
ATGAAAAATATTTCAGAATTCTCAGCCCAACTTAATCAAACTTTTGATCAAGGGGAAGCCGTCTCTATGGAGTGGTTATT
CCGTCCGTTGCTAAAAATGCTGGCGGAGGGCGATCCAGTCCCCGTTGAGGACATCGCGGCGGAGACCGGGAAGCCCGTCG
AGGAAGTTAAGCAAGTCCTACAGACTCTACCTAGTGTGGAACTTGATGAGCAGGGCCGTGTCGTCGGTTATGGCCTCACA
CTGGTCCCTACCCCCCATCGCTTCGAGGTTGATGGGAAGCAACTATATGCATGGTGCGCCCTTGACACACTTATGTTCCC
AGCACTCATCGGCCGGACGGTCCACATCGCTTCGCCTTGTCACGGCACCGGTAAGTCCGTACGGTTGACGGTGGAACCGG
ACCGCGTTGTAAGCGTCGAGCCTTCAACAGCCGTTGTCTCGATTGTTACACCAGATGAAATGGCCTCGGTTCGGTCGGCC
TTCTGTAACAACGTTCACTTTTTCAGTTCACCGAGTGCAGCCCAAGACTGGCTTAACCAACACCCTGAGTCGAGCGTTTT
GCCCGTTGAAGATGCCTTTGAACTGGGTCGCCATTTGGGAGCGCGTTATGAGGAGTCAGGACCTACTAATGGGTCCTGTT
GTAACATTTAA

Protein sequence : 
MKNISEFSAQLNQTFDQGEAVSMEWLFRPLLKMLAEGDPVPVEDIAAETGKPVEEVKQVLQTLPSVELDEQGRVVGYGLT
LVPTPHRFEVDGKQLYAWCALDTLMFPALIGRTVHIASPCHGTGKSVRLTVEPDRVVSVEPSTAVVSIVTPDEMASVRSA
FCNNVHFFSSPSAAQDWLNQHPESSVLPVEDAFELGRHLGARYEESGPTNGSCCNI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0086 NP_763641.1 alkylmercury lyase Not tested SCCpbp4 Protein 3e-99 100
merB BAB47641.1 organomercurial lyase Not tested Type-III SCCmec Protein 2e-98 99

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SE0086 NP_763641.1 alkylmercury lyase BAC0658 Protein 1e-98 99
SE0086 NP_763641.1 alkylmercury lyase BAC0663 Protein 5e-79 73
SE0086 NP_763641.1 alkylmercury lyase BAC0654 Protein 2e-79 72
SE0086 NP_763641.1 alkylmercury lyase BAC0659 Protein 8e-38 47
SE0086 NP_763641.1 alkylmercury lyase BAC0657 Protein 7e-42 47