Gene Information

Name : SE0075 (SE0075)
Accession : NP_763630.1
Strain : Staphylococcus epidermidis ATCC 12228
Genome accession: NC_004461
Putative virulence/resistance : Resistance
Product : cadmium resistance protein B
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 73390 - 75798 bp
Length : 2409 bp
Strand : +
Note : -

DNA sequence :
ATGAGTGAAGCAACGAAGCCATTAGAGGAGAAATATGTCTATCGTGTTGATGGATTTTCATGCGCAAACTGTGCAGGAAA
GTTTGAAAGAAATGTTAAAAAAATTCCGGGAGTAGAGGATGCAAAAGTAAATTTTGGAGCATCCAAAATTTCCGTTTACG
GAGAAGCAACGGTTGAAGAATTAGAAAAAGCAGGTGCCTTTGAGAACCTTAAAGTGGCTCCAGAAAAACCTAGGCGGCAG
GCTCCGCAAGAGGTTAAAAAAGACAAAAATATATATCGTGTTGAAGGGTTTTCATGCGCAAACTGTGCAGGAAAGTTTGA
AAGAAATGTTAAAAAAATTCCGGGAGTAGAGGATGCAAAAGTAAATTTTGGAGCATCCAAAATTTCCGTTTACGGAGAAG
CAACGATTGAAGAATTAGAAAAAGCAGGTGCTTTTGAGAATCTTAAAGTGGCCTCTGAAAAACCTGTACGGCAAGCTACA
CAAGAGATTAACCAGGAAAAAGAGGATGAAAAAGAAGAAAAAGTGCCATTCTATAAAAAGCACAGTACTTTACTCTATTC
GACCTTATTGATTGTTTTCGGATATCTTTCAGTCTTTGTTAATGGGGATGAGAACATTGTTACTACATTATTATTTGTAG
CATCGATGTTAATAGGAGGATTATCGCTTTTTAAAGTTGGTTTCCAAAACTTGTTACGCTTTGAATTTGACATGAAAACA
CTTATGACTGTTGCAGTTATAGGTGGTGCGATTATAGGAGAATGGGCAGAAGTTTCTGTTGTTGTCATACTCTTTGCAAT
TAGTGAAGCTCTAGAACGATTTTCTATGGATAAAGCGAGACAATCAATTCGATCATTAATGGATATTGCACCTAAAGAGG
CACTTGTTAGACGAAAAGGTCAAGAAATGATGGTTCATGTAGATGATATTGCAGTTGGAGATATTATGATTGTCAAACCT
GGTCAAAAGATTGCCATGGACGGGATGGTTGTAAGTGGGTACTCTGCTGTTAATCAAGCTGCCATTACAGGTGAGTCAGT
CCCTGTTGAAAAAGCGGTTGATGATGAAGTATTTGCAGGTACTCTAAATGAAGAAGGATTACTTGAAGTAGAAATAACTA
AATTAGTAGAAGATACAACCATTTCAAAAATTATTCATCTTGTAGAGGAAGCACAGGGAGAACGAGCACCATCTCAAGCC
TTTGTAGAAAAATTTGCGAAATATTATACTCCGATCATCATGATCATAGCTGCGTTAGTTGCTGTAGTTCCACCATTATT
CTTTGGGGCTAGTTGGGAAACATGGGTTTATCAAGGTTTAGCTGTTTTAGTCGTTGGTTGTCCATGTGCGTTGGTTATTT
CCACCCCGATTTCGATTGTTTCAGCAATTGGAAATGCAGCGAAAAAGGGTGTCCTAATAAAAGGTGGCGTTTATTTAGAA
GAAATGGGTGCCTTAAAGGCCATTGCTTTCGATAAAACAGGTACTTTGACAAAAGGTGTCCCTGTTGTAACTGACTTCAA
TGTGTTGAACAAACAGGTAGATGAAAATGAAATGCTATCCATCATTACTGCATTAGAGTATCGTTCTCAGCACCCTCTTG
CATCAGCAATCATGAAAAGAGCAGAAGAGGCGAATATTTCTTATTCAGATGTTGTGATAGATGACTTCTCTTCCATTACA
GGAAAAGGAATTAAGGGTACTGTAGACGGAACGACCTATTATATTGGAAGTCCAAAACTATTTAAGGAACTGTCAAACTC
TAGTTTTGATAAGAATTTAGAGAAAAAAGTTGCAACTCTTCAAAATCAAGGGAAAACTGCTATGGTTGTTGGAACTGACA
AAGAAATACTAGCTATTATTGCAGTAGCAGATGAAGTACGTGAATCAAGTAAAGAAGTCATTCAAAAACTACATCAACTT
GGCATCAAAAATACAATTATGCTTACCGGTGATAATAAAGGTACTGCGAATGCCATTGGAAGTCATGTCGGAGTAAAAGA
AGTTCAGGCTGAATTAATGCCTCAGGATAAATTGGATTATATTAAACAATTGAAATCGGAATACAACAACGTAGCTATGA
TTGGCGATGGTGTCAATGATGCACCTGCATTGGCAGCTTCCACTGTTGGAATTGCAATGGGTGGAGCTGGTACTGATACA
GCATTAGAAACGGCGGACGTTGCACTAATGGGAGATGATTTAAGAAAACTTCCGTTTACGGTAAAACTAAGTCGAAAAGC
GCTAAACATAATAAAAGCTAACATTACTTTTGCAATTGCTATTAAATTTATTGCCTTATTATTGGTTATTCCAGGTTGGT
TAACACTCTGGATTGCGATTCTTTCAGATATGGGTGCAACTCTTCTTGTAGCGTTGAACAGTTTACGACTTATGCGAGTG
AAAGATTAA

Protein sequence :
MSEATKPLEEKYVYRVDGFSCANCAGKFERNVKKIPGVEDAKVNFGASKISVYGEATVEELEKAGAFENLKVAPEKPRRQ
APQEVKKDKNIYRVEGFSCANCAGKFERNVKKIPGVEDAKVNFGASKISVYGEATIEELEKAGAFENLKVASEKPVRQAT
QEINQEKEDEKEEKVPFYKKHSTLLYSTLLIVFGYLSVFVNGDENIVTTLLFVASMLIGGLSLFKVGFQNLLRFEFDMKT
LMTVAVIGGAIIGEWAEVSVVVILFAISEALERFSMDKARQSIRSLMDIAPKEALVRRKGQEMMVHVDDIAVGDIMIVKP
GQKIAMDGMVVSGYSAVNQAAITGESVPVEKAVDDEVFAGTLNEEGLLEVEITKLVEDTTISKIIHLVEEAQGERAPSQA
FVEKFAKYYTPIIMIIAALVAVVPPLFFGASWETWVYQGLAVLVVGCPCALVISTPISIVSAIGNAAKKGVLIKGGVYLE
EMGALKAIAFDKTGTLTKGVPVVTDFNVLNKQVDENEMLSIITALEYRSQHPLASAIMKRAEEANISYSDVVIDDFSSIT
GKGIKGTVDGTTYYIGSPKLFKELSNSSFDKNLEKKVATLQNQGKTAMVVGTDKEILAIIAVADEVRESSKEVIQKLHQL
GIKNTIMLTGDNKGTANAIGSHVGVKEVQAELMPQDKLDYIKQLKSEYNNVAMIGDGVNDAPALAASTVGIAMGGAGTDT
ALETADVALMGDDLRKLPFTVKLSRKALNIIKANITFAIAIKFIALLLVIPGWLTLWIAILSDMGATLLVALNSLRLMRV
KD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 0.0 100
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 0.0 81
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 0.0 81

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B BAC0298 Protein 4e-127 48
SE0075 NP_763630.1 cadmium resistance protein B BAC0092 Protein 4e-100 43
SE0075 NP_763630.1 cadmium resistance protein B BAC0124 Protein 4e-92 42