Gene Information

Name : smpB (SE0566)
Accession : NP_764121.1
Strain : Staphylococcus epidermidis ATCC 12228
Genome accession: NC_004461
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 564009 - 564479 bp
Length : 471 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
GTGGCTAAGAAAAAATCAAAATCACCAGGTACGTTAGCTGAAAACCGTAAAGCAAGACATGACTACAATATTGAAGATAC
AATTGAAGCGGGTATTGCTTTAAGAGGTACTGAAATTAAATCCATACGTCGTGGTAGTGCCAATTTAAAAGATAGCTTTG
CGCAAGTGAGACGAGGCGAAATGTACCTGAATAATATGCATATTGCACCATATGAAGAAGGGAACCGTTTTAATCATGAC
CCTTTACGTACACGTAAATTACTCTTGCACAAAAAAGAAATTCAAAAATTAGGTGAGCGTACACGAGAAATAGGTTATTC
TATTATTCCGTTGAAGTTATATTTAAAACATGGTCAATGTAAAGTTTTATTAGGCGTTGCTAGAGGTAAAAAGAAATACG
ACAAACGTCAAGCACTTAAAGAAAAAGCGGTAAAACGAGATATTGATCGTGCAGTTAAAGCCCGTTATTAA

Protein sequence :
MAKKKSKSPGTLAENRKARHDYNIEDTIEAGIALRGTEIKSIRRGSANLKDSFAQVRRGEMYLNNMHIAPYEEGNRFNHD
PLRTRKLLLHKKEIQKLGERTREIGYSIIPLKLYLKHGQCKVLLGVARGKKKYDKRQALKEKAVKRDIDRAVKARY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 7e-60 89
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 2e-29 46
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 2e-24 42