Gene Information

Name : azi; div (SE2244)
Accession : NP_765799.1
Strain : Staphylococcus epidermidis ATCC 12228
Genome accession: NC_004461
Putative virulence/resistance : Unknown
Product : preprotein translocase subunit SecA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG0653
EC number : -
Position : 2302396 - 2304786 bp
Length : 2391 bp
Strand : -
Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap

DNA sequence :
ATGGCTAAAGGTGTTAACCAAATTATTAATAATATTAGGTTAAGAAAATTGCGCAAAATATTAAATCAAATTAATGCGCT
TAGTGAGGAGTTCTCAAATTTTAGTGATGAAGCACTTCAAGCGAAGACAAAAGAATTTAAAGTTTATTTAAATGATAATA
AAGCTTCACTCAATCACATTCTGCCACAAGCTTATGCAACAGTTAGAGAGGCTTCTAAGCGCGTTTTAGGTATGTATCCA
AAAGATGTGCAGATTTTAGGAGCAATCGCTATGCATCAGGGGAATATTGCAGAAATGCAAACAGGAGAAGGTAAGACGCT
TACAGCTACCATGCCTCTGTACTTAAATGCACTTACAGGTAAAGGTGCTTATCTAATCACAACAAATGATTACTTAGCAA
AACGCGATTTTTTAGAAATGAAACCACTATATGAATGGCTAGGCTTGTCTGTATCATTAGGATTTGTGGACATTCCAGAA
TATGAATACGCTGAAAATGAAAAATATGAACTGTACCACCATGACATTGTTTACACGACTAATGGGCGACTAGGGTTTGA
TTATTTAATTGATAATTTAGCTGATGATATTCGTGCCAAATTTTTACCGAAATTAAACTTTGCTATTATTGATGAAGTCG
ATTCTATTATATTAGACGCTGCCCAAACGCCTTTAGTTATTTCTGGTGCACCACGTGTACAATCTAATTTATTTCACATC
GTTAAAAAGTTTGTTGAAACACTTGAGAAAGATAAAGACTTCATAGTTAATTTTAATAAAAAAGAAGTGTGGCTCACTGA
TGAGGGCTCGGAAAAAGCAAGCCATTATTTCAAAGTGAATAGTATATACCAACAGCAATATTTTGATTTAGTTAGGATGA
TTCATTTATCGCTTAGAGCTAAGTATTTATTCAAATATAATTTAGACTATTTTATTTTTGATGGTGAGATTGTGCTTATA
GATAGAATAACTGGTCGTATGCTACCTGGAACAAAGCTTCAGTCTGGTTTACATCAAGCTATAGAGGCTCTGGAAAATGT
TGAAATTTCTCAAGATATGAGTGTGATGGCAACCATAACATTCCAAAACTTATTTAAGCAATTTGATGAATTTTCAGGTA
TGACTGGAACAGGTAAATTAGGGGAAAAAGAATTCTTTGATTTATATTCAAAAGTTGTTATAGAGATTCCGACTCACAGT
CCGATTGAACGAGATGATAGACCTGATAGAGTATTTGCTAATGGTGACAAAAAGAACGATGCAATTTTAAAGACAGTGAT
TGGTATACATGAAACTCAACAACCTGTGTTACTAATTACACGTACTGCAGAAGCGGCAGAATATTTTTCAGCTGAGTTAT
TTAAACGTGATATACCCAACAATTTATTAATCGCTCAAAATGTAGCTAAAGAGGCACAAATGATTGCTGAGGCGGGACAA
TTATCTGCAGTTACTGTTGCTACAAGTATGGCAGGGCGTGGAACTGATATAAAGTTATCAAAAGAGGTTCATGATATCGG
TGGCTTAGCAGTGATTATTAATGAACATATGGATAATAGCCGTGTTGATCGTCAATTAAGAGGACGCTCAGGTCGCCAAG
GAGATCCTGGATATTCACAGATTTTTGTATCACTTGATGATGATTTAGTAAAACGTTGGAGTAACTCTAACTTGGCAGAA
AATAAAAACCTCCAAACGATGGATGCATCTAAACTAGAAAGTAGTGCACTCTTTAAAAAACGTGTAAAGTCAATTGTTAA
TAAAGCGCAACGTGTATCTGAAGAGACTGCTATGAAAAATAGAGAAATGGCAAATGAATTCGAAAAAAGTATTAGTGTTC
AACGAGATAAAATTTATGCTGAACGTAATCACATACTTGAAGCAAGCGATTTTGATGATTTTAATTTTGAACAGCTTGCA
CGAGATGTGTTTACAAAAGACGTTAAAAATCTTGACTTAAGTAGTGAACGTGCACTTGTGAATTATATATACGAAAACTT
AAGTTTTGTCTTCGATGAAGATGTATCAAATATTAATATGCAAAATGATGAAGAAATCATACAATTCTTAATACAACAAT
TTACTCAACAATTTAACAATCGTTTAGAAGTTGCTGCTGATTCATATTTAAAACTTCGTTTCATTCAAAAATCAATTTTG
AAAGCGATAGATAGCGAATGGATTGAACAAGTAGATAACTTACAACAACTTAAAGCCAGTGTAAACAATCGACAAAATGG
ACAGCGTAATGTCATTTTTGAATATCATAAAGTGGCTCTTGAAACGTATGAATATATGTCTGAAGATATAAAAAGGAAGA
TGGTTAGAAATTTATGTTTAAGTATTCTAGCCTTTGATAAGGACGGAGATATGGTCATTCATTTCCCATAA

Protein sequence :
MAKGVNQIINNIRLRKLRKILNQINALSEEFSNFSDEALQAKTKEFKVYLNDNKASLNHILPQAYATVREASKRVLGMYP
KDVQILGAIAMHQGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAKRDFLEMKPLYEWLGLSVSLGFVDIPE
YEYAENEKYELYHHDIVYTTNGRLGFDYLIDNLADDIRAKFLPKLNFAIIDEVDSIILDAAQTPLVISGAPRVQSNLFHI
VKKFVETLEKDKDFIVNFNKKEVWLTDEGSEKASHYFKVNSIYQQQYFDLVRMIHLSLRAKYLFKYNLDYFIFDGEIVLI
DRITGRMLPGTKLQSGLHQAIEALENVEISQDMSVMATITFQNLFKQFDEFSGMTGTGKLGEKEFFDLYSKVVIEIPTHS
PIERDDRPDRVFANGDKKNDAILKTVIGIHETQQPVLLITRTAEAAEYFSAELFKRDIPNNLLIAQNVAKEAQMIAEAGQ
LSAVTVATSMAGRGTDIKLSKEVHDIGGLAVIINEHMDNSRVDRQLRGRSGRQGDPGYSQIFVSLDDDLVKRWSNSNLAE
NKNLQTMDASKLESSALFKKRVKSIVNKAQRVSEETAMKNREMANEFEKSISVQRDKIYAERNHILEASDFDDFNFEQLA
RDVFTKDVKNLDLSSERALVNYIYENLSFVFDEDVSNINMQNDEEIIQFLIQQFTQQFNNRLEVAADSYLKLRFIQKSIL
KAIDSEWIEQVDNLQQLKASVNNRQNGQRNVIFEYHKVALETYEYMSEDIKRKMVRNLCLSILAFDKDGDMVIHFP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
secA2 YP_006310687.1 preprotein translocase subunit SecA2 Not tested FWisland_3 Protein 6e-156 46