Gene Information

Name : leuS (SE1431)
Accession : NP_764986.1
Strain : Staphylococcus epidermidis ATCC 12228
Genome accession: NC_004461
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1481474 - 1483918 bp
Length : 2445 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGTCTTTTTATGAATTAGGAGGAAATGTGTTGAATTATAATCATAAGGAAATTGAAAAAAAGTGGCAGAATTACTGGGA
AGAAAATAAGACCTTTAAAACGAATGATAATTTAGGACAAAAGAAATTTTATGCATTAGACATGTTTCCTTATCCATCTG
GTGCTGGTTTACACGTAGGTCATCCAGAAGGATATACGGCAACGGATATCATCTCACGATATAAAAGAATGCAAGGTTAC
AATGTATTACATCCTATGGGGTGGGATGCTTTTGGTTTGCCGGCAGAACAATATGCTTTAGATACTGGTAATGATCCTCG
TGAATTTACACAGAAAAATATTCAAACTTTCAAAAGACAAATTCAAGAATTAGGATTTAGTTATGATTGGGATAGAGAAG
TGAATACTACAGATCCTGAATATTATAAATGGACGCAGTGGATATTTATTCAGTTGTATAATAAAGGGTTAGCTTATGTT
GATGAAGTTGCTGTCAATTGGTGTCCTGCATTAGGTACTGTTTTGTCGAATGAAGAGGTTGTCGATGGGGTATCAGAACG
TGGCGGTCATCCTGTTTATCGTAAGCCTATGAAACAATGGGTACTCAAAATTACAGAATATGCTGATAGATTACTAGAAG
ATTTAGATGAGTTAGATTGGCCTGAATCAATTAAAGACATGCAACGAAACTGGATTGGACGTTCAGAAGGTGCCAAAGTA
ACATTTAAAATTGAGCAATCTGACCAAAATATTGAAGTGTTTACGACACGACCAGATACAATCTATGGTACTTCTTTCTT
AGTTTTAAGCCCAGAACACCCACTTGTGAATGAAATTACGACAAGTGATAAAGAACAAGAAGTCAAATTGTATCAAAATG
AAGCATCAAAAAAATCTGATTTAGAACGTACGGACTTAGCTAAAGAAAAAACAGGTGTGTTTACTGGAACATTTGCAATT
AATCCGCTCTCTGGCGATAAATTACCTATTTGGATAGCAGATTATGTTTTATCAACTTACGGTACTGGTGCAGTAATGGC
TGTGCCTGGACATGATGAGCGAGATCATGAATTTGCTACGAAGTTTAATTTACCAATTATCGAAGTTATAGAGGGTGGCG
AAGTTCAAAAATATGCATACACAGGTGAAGGAAAACACATTAATTCTGGAGAATTAGACGGTCTAGAAAATGAAGCGGCA
ATAAGTAAAGCGATAGAATTGCTTGAATCTAAAGGTGCTGGTGAGAAAAAAGTCAATTATAAATTACGTGATTGGTTATT
TAGTAGGCAACGTTATTGGGGAGAACCAATTCCTATTATACATTGGGAAGATGGATCAATGACTACAGTTCCTGAAGATG
AATTGCCTTTACTACTTCCTGAAACAGATGAAATTAAGCCATCAGGTACCGGTGAATCTCCACTTGCAAATATAGATGCG
TTCGTAAACGTTATCGATGAAAAGACAGGTATGAAGGGGCGCCGAGAAACCAATACAATGCCTCAATGGGCTGGCAGTTG
CTGGTACTATTTACGTTACATTGATCCACATAACGAAAAAATGATAGCAGATCCTGAAAAATTAAAGCATTGGCTACCTG
TTGATTTATATATTGGAGGCGTGGAACATGCAGTACTTCACTTATTATATGCAAGATTCTGGCATAAAGTGTTATATGAC
TTAGGTGTTGTACCAACAAAAGAACCATTCCAAAAACTATACAATCAGGGAATGATTTTAGGCGAAGGCAATGAAAAAAT
GAGTAAGTCTAAAGGTAATGTGATTAATCCAGATGATATTGTTGCATCACATGGTGCTGATACATTACGACTATATGAAA
TGTTTATGGGACCTTTAGATGCTGCGATCGCATGGAGTGAAAAAGGTTTAGATGGTTCTAGAAGATTCTTAGATCGTGTT
TGGAGACTTATCATTACTGATGAAAATTCAATCAATAAAAAAATTGTAGATTCTAACAATCATTCACTTGATAAGGTTTA
CAATCAAACTGTGAAAAAAGTAACAGAAGATTTTGATACACTTAGTTTTAATACTGCAATCAGTCAATTAATGGTGTTTA
TTAATGAGTGTTATAAAACCAATGAAGTTTACAAACCTTATATCGAAGGGTTTGTAAAAATGTTATCGCCTATTGCACCA
CACATTGGTGAAGAATTATGGGATCGATTAGGGCATGAAAATACCATTACTTATCAACCATGGCCAACATTTGATGAAAG
TTTATTAGTAGATGATGAAGTTGAAATCGTAGTTCAAGTCAATGGTAAAGTTAGAGCAAAAATCAATATTCCAAAAGATT
TATCTAAAGAAGAAATGCAAGACTTAGCCTTGTCTAATGATAATGTTAAAATGAGTATTGAAGGAAAAGAAGTTAAAAAA
GTTATTGCTGTACCTCAAAAGCTAGTTAATATAGTTGCTAAATAA

Protein sequence :
MSFYELGGNVLNYNHKEIEKKWQNYWEENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIISRYKRMQGY
NVLHPMGWDAFGLPAEQYALDTGNDPREFTQKNIQTFKRQIQELGFSYDWDREVNTTDPEYYKWTQWIFIQLYNKGLAYV
DEVAVNWCPALGTVLSNEEVVDGVSERGGHPVYRKPMKQWVLKITEYADRLLEDLDELDWPESIKDMQRNWIGRSEGAKV
TFKIEQSDQNIEVFTTRPDTIYGTSFLVLSPEHPLVNEITTSDKEQEVKLYQNEASKKSDLERTDLAKEKTGVFTGTFAI
NPLSGDKLPIWIADYVLSTYGTGAVMAVPGHDERDHEFATKFNLPIIEVIEGGEVQKYAYTGEGKHINSGELDGLENEAA
ISKAIELLESKGAGEKKVNYKLRDWLFSRQRYWGEPIPIIHWEDGSMTTVPEDELPLLLPETDEIKPSGTGESPLANIDA
FVNVIDEKTGMKGRRETNTMPQWAGSCWYYLRYIDPHNEKMIADPEKLKHWLPVDLYIGGVEHAVLHLLYARFWHKVLYD
LGVVPTKEPFQKLYNQGMILGEGNEKMSKSKGNVINPDDIVASHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLDRV
WRLIITDENSINKKIVDSNNHSLDKVYNQTVKKVTEDFDTLSFNTAISQLMVFINECYKTNEVYKPYIEGFVKMLSPIAP
HIGEELWDRLGHENTITYQPWPTFDESLLVDDEVEIVVQVNGKVRAKINIPKDLSKEEMQDLALSNDNVKMSIEGKEVKK
VIAVPQKLVNIVAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 66