Gene Information

Name : SE1373 (SE1373)
Accession : NP_764928.1
Strain : Staphylococcus epidermidis ATCC 12228
Genome accession: NC_004461
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 1406077 - 1407834 bp
Length : 1758 bp
Strand : -
Note : -

DNA sequence :
ATGAGAAAGACTAAAATTGTATGTACAATAGGACCAGCTTCAGAATCAGAGGAAATGCTCGAAAAACTAATGAATGCAGG
AATGAACGTTGCGCGTTTAAATTTCTCACATGGTAGTCATGAAGAACATAAAGCAAGAATTGATACAATTCGTAAAGTTG
CTAAACGTTTAAATAAAACAATTGGCTTGTTATTGGATACTAAAGGGCCAGAAATTCGTACTCACAATATGAAAGATGGA
CTTATTGTTTTAGAAAAAGGCAAAGAAGTCATTGTAAGCATGAATGAAGTTGAAGGAACACCTGAAAAATTCTCTGTAAC
ATATGAAAATCTAATCAATGATGTCAATATTGGATCATATATACTATTAGATGATGGTTTAGTTGAACTTCAAGTCAAAG
AAATTAACAAAGATAAAGGCGAAGTTAAATGTGATATCTTAAATACTGGTGAATTAAAAAATAAAAAAGGTGTTAACTTA
CCTGGTGTTAAAGTTAATTTACCTGGTATCACTGATAAAGATGCCGATGATATCAGATTTGGTATAAAGGAAAATGTAGA
CTTTATAGCTGCAAGTTTTGTAAGACGTCCAAGTGATGTTTTAGATATCCGTCAAATTCTTGAAGAAGAAAAAGCAGAAA
TAACAATTTTCCCTAAAATTGAAAACCAAGAAGGTATCGATAATATTGAAGAAATTCTTGAAGTATCTGATGGATTAATG
GTAGCACGTGGTGATATGGGTGTTGAAATTCCGCCAGAAAGCGTACCAATGGTTCAAAAAGATTTAATTAGAAAATGTAA
TAAATTAGGAAAACCTGTAATTACTGCGACTCAAATGCTTGATTCTATGCAACGTAATCCACGTGCGACACGTGCAGAAG
CAAGTGACGTAGCTAATGCAATATACGATGGTACTGACGCGGTAATGTTATCAGGTGAAACTGCAGCAGGTCAATATCCT
GAAGAAGCTGTTAAAACTATGCGTAATATTGCAGTTTCTGCTGAAGCAGCGCAAGACTATAAAAAATTATTAAGTGATCG
TACTAAATTAGTTGAAACTTCATTAGTAAATGCAATTGGTGTTTCTGTTGCACATACTGCCTTAAACTTAAATGTAAAAG
CTATTGTAGCAGCAACTGAAAGTGGTTCAACAGCACGTACGATTTCTAAATATCGTCCACATTCAGATATCATTGCTGTA
ACACCTAGCGAAAAAACTGCTAGACAATGTGCAATTGTATGGGGAGTAAATCCGGTCGTTAAAGAAGGACGTAAAACAAC
TGATGCTTTACTAAATAATGCTGTAGCAACAGCAGTAGAAACTGGTAGAGTTTCAAACGGAGATTTAATTATTATTACTG
CTGGTGTACCTACTGGAGAAAAAGGAACTACAAATATGATGAAAATCCACTTAGTAGGTGATGAGATTGCTAAAGGTCAA
GGTGTTGGTAGAGGATCTGTTGTAGGCCATGCAATTGTCGCAGATAGTGCTAGTGATTTAGAAGGTAAAGATTTATCTGA
TAAAGTTATTATTACAAATTCTGTTGATGAAACATTAGTACCATATGTTGAAAAAGCTATAGGTCTAATTACAGAAGAAA
ATGGTATTACTTCACCAAGCGCAATTATAGGTTTAGAAAAAGGCATACCTACTGTTGTTGGTGTAGAACAAGCAACCAAA
GAAATTAAAAATGATATGTTAGTGACTTTAGATGCGTCACAAGGTAAAGTGTTTGAAGGTTATGCTAACGTCCTTTAA

Protein sequence :
MRKTKIVCTIGPASESEEMLEKLMNAGMNVARLNFSHGSHEEHKARIDTIRKVAKRLNKTIGLLLDTKGPEIRTHNMKDG
LIVLEKGKEVIVSMNEVEGTPEKFSVTYENLINDVNIGSYILLDDGLVELQVKEINKDKGEVKCDILNTGELKNKKGVNL
PGVKVNLPGITDKDADDIRFGIKENVDFIAASFVRRPSDVLDIRQILEEEKAEITIFPKIENQEGIDNIEEILEVSDGLM
VARGDMGVEIPPESVPMVQKDLIRKCNKLGKPVITATQMLDSMQRNPRATRAEASDVANAIYDGTDAVMLSGETAAGQYP
EEAVKTMRNIAVSAEAAQDYKKLLSDRTKLVETSLVNAIGVSVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAV
TPSEKTARQCAIVWGVNPVVKEGRKTTDALLNNAVATAVETGRVSNGDLIIITAGVPTGEKGTTNMMKIHLVGDEIAKGQ
GVGRGSVVGHAIVADSASDLEGKDLSDKVIITNSVDETLVPYVEKAIGLITEENGITSPSAIIGLEKGIPTVVGVEQATK
EIKNDMLVTLDASQGKVFEGYANVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 6e-94 48
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 4e-94 48
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 4e-94 48
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-93 48
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 5e-57 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SE1373 NP_764928.1 pyruvate kinase VFG0479 Protein 2e-94 48