Gene Information

Name : hemC (SE1345)
Accession : NP_764900.1
Strain : Staphylococcus epidermidis ATCC 12228
Genome accession: NC_004461
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1374644 - 1375570 bp
Length : 927 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGCGTAAATTAATTGTTGGGTCGCGAAGAAGTAAATTAGCGCTAACACAAAGTCAACAATTTATAGATAAATTAAAATT
TATCGATCCGTCTTTGGATATTGAAATAAAAGAAATTGTAACTAAAGGCGACAAAATTGTAGATAAACAATTATCCAAAG
TTGGAGGTAAAGGACTTTTTGTTAAGGAAATCCAAAATGAATTATTTAATAAAGAGATAGATATGGCGATTCATTCTCTA
AAAGATGTACCAAGTATGATTCCTGACGGTCTTACCTTAGGATGTATTCCTGACAGAGAAATTCCTTTTGATGCCTATAT
AGCAAAAAATCATATACCATTACAAGAATTGTCTGAGGGCAGCATTGTAGGTACAAGTTCTTTACGTCGTGGCGCTCAAA
TTTTATCAAAATACCCACATTTAAAAATTAAGTGGATTCGTGGAAACATTGATACTCGATTAAAAAAATTAGAGACTGAA
GATTATGATGCTATTATATTAGCTGCTGCTGGATTAAAACGCATGGGTTGGTCAGATAATATTGTTACGACTTATCTTGA
TCGAGATATATTACTGCCAGCTATAGGGCAGGGTGCACTTGGTATTGAGTGTAGGAGTGATGACAAAGAACTTTTAGATT
TACTATCTAAAGTACACAATCATGATGTAGCACAATGTGTGACTGCTGAACGTACTTTTCTATCAGAAATGGATGGCAGT
TGTCAGGTTCCTATAGGTGGATATGCAACAATTGCTCAAGATAACCAAATTGAATTTACAGGACTGATTATGTCTCCAGA
TGGTAAGGAAAGATATGAGCATACAGCATTGGGTACTGATCCTGTAAAATTGGGTATAGAAGTGAGTCAAGTACTTAAAA
AACAAGGTGCTTATGACATAATTAAAAAATTAAACGAAGCAGAATAA

Protein sequence :
MRKLIVGSRRSKLALTQSQQFIDKLKFIDPSLDIEIKEIVTKGDKIVDKQLSKVGGKGLFVKEIQNELFNKEIDMAIHSL
KDVPSMIPDGLTLGCIPDREIPFDAYIAKNHIPLQELSEGSIVGTSSLRRGAQILSKYPHLKIKWIRGNIDTRLKKLETE
DYDAIILAAAGLKRMGWSDNIVTTYLDRDILLPAIGQGALGIECRSDDKELLDLLSKVHNHDVAQCVTAERTFLSEMDGS
CQVPIGGYATIAQDNQIEFTGLIMSPDGKERYEHTALGTDPVKLGIEVSQVLKKQGAYDIIKKLNEAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 8e-58 46
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 8e-58 46