Gene Information

Name : VV2_0840 (VV2_0840)
Accession : NP_762773.1
Strain :
Genome accession: NC_004460
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : 2.7.7.58
Position : 907474 - 909102 bp
Length : 1629 bp
Strand : -
Note : COG1021

DNA sequence : 
ATGGTCGTCGCGACAACCGAAACACCAAAGCAGATACTCGATGGCTTTGTGCGTAAACCTAGTATTCAACGTGAACAATA
TCAGGCTGCAAATTTGTGGCGCAATTTGCCGCTGTGGCAAATTCTTCATCAGGGAGTAGAGCGTCACCCTGATAGGATAG
CGGTGACCGATAACCACACTTCACTGAGCTATCTCGAGTTGGCCAATCATGTGGATAGGATCGCTGCTGGGTTGCGAGAA
GAAGGGCTTGTGTGTGGTGACAGTGTTGTCTTGCAGCTAGCCAATACACTCGATTTTCTCGTCGTGTTTTTTGCTCTTCA
GCGCCTTGGTGTGGTTCCCGTACTGGCATTACCTGCACACGGTTTGGTCGAAATTCGCCACTTTATGCAACTCTCTGAGG
CAAAAGTGTACATCGGCTCCAATCATGAAAAGGATGACAAAGCGTTGGCGATTGCCACTCAGTTGCAAGCGGAACTATCA
GTGTCCATACGCTGCTATATCAGCGGGCATTTTGGTCAATTTTCGCCGTTGCCAGAGTGTGACGCTGGCGATTTTACACC
AGCGATGGTAGACCCAGAACACCCGGCACTTTTCCTCGTTTCTGGAGGCACGACAGGGCTACCCAAACTTATCCCCCGAA
CTCACAATGATTATCTGTTTAATGTTGAGCAATGTGCGAAAGCCAGTGAAATCAGCGCGCAGGATGTGTATTTGGCGGTG
TTGCCTGCGGCACACAATTTTACCTTGGGCTGTCCTGGGATCTTAGGGGTGTTGAATGCTGGCGGCAAAGTGGTTTTGAC
CACCAACCCAAGCCCAGATTATTGTTTTGAACTTATTGAAAAACAGTGTATTACCGCAACGGCGTTGGTGCCTGCATTGG
CGCAGCTGTGGACGGAGGCAACTCAATGGGAGTCGACGGATCGTTCGAGTTTGCGTTTGATGCAAGTCGGTGGTTCCAAG
CTTGCCTATAGCGATGCGCTGGAAATGCAAAACGCCTTTCCAAACGCGTTGCAGCAAGTTTTTGGTATGGCGGAAGGTTT
GATTGCGTGTACCCGTTTGGGCGACGACAAAGAAATTATTGCAACAAGGCAAGGTCGTCCTGTCAGCGAATGGGACGAGG
TCCTCGTTGTGGATGATCAAGGCAAGCCAGTTGCGATTGGAGAGGAAGGGGAACTGCTGACCCGAGGGCCTTACACGCTT
AGCGGATATTACCGTGCGCCAGAGCATAATCTGCGGGCGTTTACGGATGAAGGGTATTATCGCAGTGGCGATCGCGTGGT
CGTCGATGCCAACGGTTACTTCACGGTCACTGGACGGATAAAGGATGTGATCATTCGTGCTGGCGAAAACATTGCTGCTG
ATGAGTTAGAAGAGCTCTTATTGTCGCATCCACAAATTGCCCAAGTAGCGGTGTTTCCCCTGCCAGATGCTCATTTAGGT
GAAAAAATCGCCGTCGCCGCCGTCATTCGAGGTCCCGAAATTATGTTGCGAGACATTCGGCAATTTCTCCAAACCAAAGA
GATCGCCGCATTCAAACTTCCTGATGAACTGTTTGCGGTCAAATCGTTGCCAAAAACGGCCGTAGGTAAAATCGACAAGA
AGCGCATTTTAAGCACCATTCTGCCGTGA

Protein sequence : 
MVVATTETPKQILDGFVRKPSIQREQYQAANLWRNLPLWQILHQGVERHPDRIAVTDNHTSLSYLELANHVDRIAAGLRE
EGLVCGDSVVLQLANTLDFLVVFFALQRLGVVPVLALPAHGLVEIRHFMQLSEAKVYIGSNHEKDDKALAIATQLQAELS
VSIRCYISGHFGQFSPLPECDAGDFTPAMVDPEHPALFLVSGGTTGLPKLIPRTHNDYLFNVEQCAKASEISAQDVYLAV
LPAAHNFTLGCPGILGVLNAGGKVVLTTNPSPDYCFELIEKQCITATALVPALAQLWTEATQWESTDRSSLRLMQVGGSK
LAYSDALEMQNAFPNALQQVFGMAEGLIACTRLGDDKEIIATRQGRPVSEWDEVLVVDDQGKPVAIGEEGELLTRGPYTL
SGYYRAPEHNLRAFTDEGYYRSGDRVVVDANGYFTVTGRIKDVIIRAGENIAADELEELLLSHPQIAQVAVFPLPDAHLG
EKIAVAAVIRGPEIMLRDIRQFLQTKEIAAFKLPDELFAVKSLPKTAVGKIDKKRILSTILP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-92 46
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-92 46
ybtE CAA21394.1 - Virulence HPI Protein 3e-92 46
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 2e-92 46
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 2e-92 46
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-92 46
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 3e-92 46
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 1e-91 46
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-91 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
VV2_0840 NP_762773.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 4e-105 47
VV2_0840 NP_762773.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 1e-102 46
VV2_0840 NP_762773.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 6e-89 42