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Name : lysS (MYPE8420) Accession : NP_758230.1 Strain : Mycoplasma penetrans HF-2 Genome accession: NC_004432 Putative virulence/resistance : Virulence Product : lysyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG1190 EC number : - Position : 1122982 - 1124451 bp Length : 1470 bp Strand : - Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA DNA sequence : ATGGAAAGAAAATTTAATGATCAAGAATTAATAAGAAGAGAAAAGTTAAAAAATTTACAAGAAGCAAATCAAGATCCTTA TGAAATTGAAAAAGTTTCTAGAACAATGACTATAGGAGATTTTAATAGTAAGTTTGCAAAATTAAAAACTCATAACACTA ATAACAATATTAAGTTAGCTGGAAGAGTTGTTGCTTTAAGACAAACTTTTGGTGTTATTAGAGATTTTTATGGAGATACT CAATTTTATTTAAATAAGAAAAAAGTAAGCAAATCAATGCTTGAGTATTTTAATAAAGTATTAGATTTAGGTGATATTGT AGAAATTTTTGGATCTCCTTTTAGAACACAAAAAGGTGAATTAACTTTAGATGTTAAAAAAATTAAAATAGTATCAAAAG CTTTAAAACCACTACCTGAAAAATGGCATGGTTTAGAAGATGAAGAATTAAGAGCAAGACACAGATATGTTGATTTAATT GTTAATAAAGATTCTATGAAAGTGTTTGTAGACAGAATTAGAATTCTTAAAATAATTCGTCAATTCATGGATTCTCAAAA TTATCTAGAAGTTGAAACTCCAGTTCTTCACCCTATTTTAGGTGGTGCTAATGCTAGACCTTTTATAACTTTTCATAATA CTTTGGAAAGAAACTTTTATTTAAGAATTGCTACTGAATTACCACTAAAAAAATTGATAGTTGGTGGTTTTGATAAAGTT TATGAGATTGGTAGAATATTTAGAAATGAAGGGATGGATTCAACTCATAACCCTGAGTTTACTAGTATGGAAGTTTATGC TGCATATGAAAACATGGAATATATGATGAGATTAACTGAAAACCTTTTCAAATATGTTGCTAAATCACTGAAAAAACCAG TTGTTAAAATGGGGGAAAATGAAATATATTTAACTCAAAAATTCAGAAGAATTCATATGGTTGATTTTATTAAGCAAGAA ACTGGAGTAGATTTTTGAGAAGTAAAATCTAATCAAGAAGCACAAGAACTTGCTAAAAAACATAATGTAAAATTTGAAAA GCACCAATCAACATTAGGTCATATTATTAATTTATTTTTTGAAGAATTCTGTGAAGCTAAATGTATTCAACCAACATTTG TTTATGGACATCCAATTGATGTTTCTCCATTATCTAAAAAAGATTATAAAAACCCAGGGTTTACAAAAAGATTTGAATTA TTTATTAATACTAAAGAATATGCAAATGCATTTGCTGAGTTAAATGATCCAATTGATCAATATGAAAGATTTGAAGCTCA AGTAAAAGAAAAATCATTAGGTAATGATGAAGCTGTTGAAATGGATATGGATTTCATTGAGGCTTTAGAATATGGTCTTC CACCAACTGCAGGATTAGGTGTGGGAATTGATAGAATGATTATGTTATTTACTGAAAAATCAAGTATTAGAGATGTATTG CTATTCCCTCACATGAAAGATAAAAAATAA Protein sequence : MERKFNDQELIRREKLKNLQEANQDPYEIEKVSRTMTIGDFNSKFAKLKTHNTNNNIKLAGRVVALRQTFGVIRDFYGDT QFYLNKKKVSKSMLEYFNKVLDLGDIVEIFGSPFRTQKGELTLDVKKIKIVSKALKPLPEKWHGLEDEELRARHRYVDLI VNKDSMKVFVDRIRILKIIRQFMDSQNYLEVETPVLHPILGGANARPFITFHNTLERNFYLRIATELPLKKLIVGGFDKV YEIGRIFRNEGMDSTHNPEFTSMEVYAAYENMEYMMRLTENLFKYVAKSLKKPVVKMGENEIYLTQKFRRIHMVDFIKQE TGVDFWEVKSNQEAQELAKKHNVKFEKHQSTLGHIINLFFEEFCEAKCIQPTFVYGHPIDVSPLSKKDYKNPGFTKRFEL FINTKEYANAFAELNDPIDQYERFEAQVKEKSLGNDEAVEMDMDFIEALEYGLPPTAGLGVGIDRMIMLFTEKSSIRDVL LFPHMKDKK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| unnamed | CAD66193.1 | putative lysil-tRNA synthetase LysU | Not tested | PAI III 536 | Protein | 6e-88 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| lysS | NP_758230.1 | lysyl-tRNA synthetase | VFG1668 | Protein | 3e-88 | 42 |
