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Name : leuS (c0733) Accession : NP_752663.1 Strain : Escherichia coli CFT073 Genome accession: NC_004431 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 712192 - 714915 bp Length : 2724 bp Strand : - Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGAATAATCCGGGCATCATTTCAACGTCGAGTGCGCGAAAGGCTGTTTTGACGCGGGCGTTTGGGCTATGCTATGCGGA TCTGAAAAACCACATCAACGCTACATTTGTAGCCGTATTGAAAACAGGACCACTGGCTGCCATGCAAGAGCAATACCGCC CGGAAGAGATAGAATCCAAAGTACAGCTTCACTGGGATGAGAAGCGCACATTTGAAGTAACCGAAGACGAGAGCAAAGAG AAGTATTACTGCCTGTCTATGCTTCCCTATCCTTCTGGTCGACTACACATGGGCCACGTTCGCAACTACACCATCGGTGA CGTGATCGCCCGCTACCAGCGCATGCTGGGCAAAAACGTCCTGCAGCCAATCGGCTGGGACGCATTTGGTCTGCCTGCGG AAGGCGCGGCGGTGAAAAACAACACCGCGCCAGCACCGTGGACGTACGACAACATCGCGTATATGAAAAACCAGCTCAAA ATGCTGGGCTTTGGTTATGACTGGAGCCGCGAGCTGGCGACCTGTACGCCGGAATACTACCGTTGGGAACAGAAATTCTT CACCGAACTGTATAAAAAAGGCCTGGTATATAAGAAGACTTCTGCGGTCAACTGGTGCCCGAACGACCAGACCGTACTGG CGAACGAACAAGTTATCGACGGCTGCTGCTGGCGCTGCGATACCAAAGTTGAGCGTAAAGAGATCCCGCAGTGGTTTATC AAAATCACTGCTTACGCTGACGAGCTGCTCAACGATCTGGATAAACTGGATCACTGGCCAGACACCGTTAAAACAATGCA GCGTAACTGGATCGGTCGTTCCGAAGGCGTGGAAATCACCTTCAACGTTAACGACTATGACAACACGCTGACCGTTTACA CTACCCGCCCGGACACCTTTATGGGTTGTACCTACCTGGCGGTGGCTGCGGGTCATCCGCTGGCACAGAAAGCGGCGGAA AATAATCCTGAACTGGCCGCCTTTATTGACGAATGCCGTAACACCAAAGTTGCCGAAGCTGAAATGGCGACGATGGAGAA AAAAGGCGTCGATACTGGCTTTAAAGCGGTTCACCCATTAACGGGCGAAGAAATTCCCGTTTGGGCAGCAAACTTCGTAT TGATGGAATACGGCACGGGCGCAGTTATGGCAGTTCCGGGTCACGACCAGCGCGACTACGAGTTTGCCTCTAAATACGGC CTGAACATCAAACCGGTTATCCTGGCAGCTGACGGCTCTGAGCCAGATCTTTCTCAGCAAGCCCTGACTGAAAAAGGCGT GCTGTTCAACTCTGGCGAGTTTAATGGTCTTGACCATGAAGCGGCCTTCAACGCCATCGCCGATAAACTGACTGCGATGG GCGTTGGCGAGCGTAAAGTGAACTACCGCCTGCGCGACTGGGGTGTTTCTCGTCAGCGTTACTGGGGCGCGCCGATTCCG ATGGTGACGCTGGAAGACGGTACCGTAATGCCGACCCCGGACGACCAGCTGCCGGTGATCCTGCCGGAAGATGTGGTGAT GGACGGCATTACCAGCCCGATTAAAGCAGATCCGGAATGGGCAAAAACTACCGTTAACGGTATGCCAGCACTGCGTGAAA CCGACACTTTCGACACCTTTATGGAGTCCTCCTGGTACTATGCGCGCTACACTTGCCCGGAGTACAAAGAAGGTATGCTG GATTCCAAAGCGGCTAACTACTGGCTGCCGGTGGATATTTACATTGGTGGTATCGAACACGCCATTATGCACCTGCTCTA CTTCCGCTTCTTCCACAAACTGATGCGTGATGCAGGCATGGTGAACTCTGACGAACCAGCGAAACAGTTGCTGTGTCAGG GTATGGTGCTGGCAGATGCCTTCTACTATGTTGGTGAAAACGGCGAACGTAACTGGGTTTCCCCGGTTGATGCTATCGTT GAACGTGACGAGAAAGGCCGTATCGTGAAAGCGAAAGATGCGGCAGGCCATGAACTGGTTTATACCGGCATGAGCAAAAT GTCCAAGTCGAAGAACAACGGTATCGACCCGCAGGTGATGGTTGAACGTTACGGCGCGGACACCGTTCGTCTGTTTATGA TGTTTGCTTCTCCGGCTGATATGACTCTCGAATGGCAGGAATCCGGCGTGGAAGGGGCTAACCGCTTCCTGAAACGTGTC TGGAAACTGGTGTACGAGCACACAGCAAAAGGTGATGTTGCGGCACTGAACGTCGATGCGCTGACTGAAGATCAGAAAGC GCTGCGTCGCGATGTGCATAAAACTATCGCTAAAGTAACCGATGATATCGGCCGTCGTCAGACCTTCAACACCGCAATTG CGGCGATTATGGAGCTGATGAACAAACTGGCGAAAGCACCGACCGATGGCGAGCAGGATCGCGCCCTGATGCAGGAAGCG CTGCTGGCGGTAGTCCGTATGCTTAACCCGTTCACCCCGCACATCTGCTTCACGCTGTGGCAGGAACTGAAAGGCGAAGG CGATATCGACAACGCGCCGTGGCCGGTTGCTGACGAAAAAGCGATGGTGGAAGACTCCACGCTGGTCGTGGTGCAGGTTA ACGGTAAAGTCCGTGCAAAAATCACCGTTCCGGTGGACGCAACGGAAGAACAGGTTCGCGAACGTGCTGGCCAGGAACAT CTGGTAGCAAAATATCTTGATGGCGTTACTGTACGTAAAGTGATTTACGTACCCGGTAAACTCCTCAATCTGGTCGTTGG CTAA Protein sequence : MNNPGIISTSSARKAVLTRAFGLCYADLKNHINATFVAVLKTGPLAAMQEQYRPEEIESKVQLHWDEKRTFEVTEDESKE KYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLK MLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFI KITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDTFMGCTYLAVAAGHPLAQKAAE NNPELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYG LNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIP MVTLEDGTVMPTPDDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPEYKEGML DSKAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIV ERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRV WKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEA LLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEH LVAKYLDGVTVRKVIYVPGKLLNLVVG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 6e-155 | 42 |
