Gene Information

Name : pepA (c5360)
Accession : NP_757208.1
Strain : Escherichia coli CFT073
Genome accession: NC_004431
Putative virulence/resistance : Unknown
Product : leucyl aminopeptidase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0260
EC number : 3.4.11.1
Position : 5103374 - 5104885 bp
Length : 1512 bp
Strand : -
Note : catalyzes the removal of N-terminal amino acids preferably leucine from various peptides

DNA sequence :
ATGGAGTTTAGTGTAAAAAGCGGTAGCCCGGAGAAACAGCGGAGTGCCTGCATCGTCGTGGGCGTCTTCGAACCACGTCG
CCTTTCTCCGATTGCAGAACAGCTCGATAAAATCAGCGATGGGTACATCAGCGCCCTGCTACGTCGGGGCGAACTGGAAG
GAAAACCGGGGCAGACATTGTTGCTGCACCATGTGCCGAATGTACTTTCCGAGCGAATTCTCCTTATTGGTTGCGGCAAA
GAACGTGAGCTGGATGAGCGTCAGTACAAGCAGGTTATTCAGAAAACCATTAATACGCTGAATGATACTGGCTCAATGGA
AGCGGTCTGCTTTCTGACTGAACTGCACGTTAAAGGCCGTAACAACTACTGGAAAGTGCGTCAGGCTGTCGAGACGGCAA
AAGAGACGCTCTACAGTTTCGATCAGTTGAAAACGAACAAGAGCGAACCGCGTCGTCCGCTGCGTAAAATGGTGTTCAAC
GTGCCGACCCGCCGTGAGCTGACCAGCGGTGAACGCGCGATCCAGCATGGTCTGGCGATTGCCGCAGGGATTAAAGCCGC
GAAAGATCTCGGCAATATGCCACCGAATATCTGTAACGCTGCTTACCTCGCCTCTCAGGCGCGCCAGTTGGCTGACAGCT
ACAGCAAGAATGTCATCACCCGCGTTATCGGCGAACAGCAGATGAAAGAGCTGGGGATGCATTCCTATCTGGCGGTCGGT
CAGGGTTCGCAAAACGAATCGCTGATGTCAGTGATTGAGTACAAAGGCAACGCGTCGGAAGATGCACGCCCAATCGTGCT
GGTGGGTAAAGGTTTAACCTTCGACTCCGGCGGTATCTCGATCAAGCCTTCAGAAGGCATGGATGAGATGAAGTACGATA
TGTGCGGTGCGGCAGCGGTCTACGGCGTGATGCGTATGGTCGCGGAGCTACAACTGCCGATTAACGTTATCGGCGTGCTG
GCAGGCTGCGAAAACATGCCTGGCGGTCGTGCCTATCGTCCGGGCGATGTGTTAACCACCATGTCCGGTCAAACCGTAGA
AGTGCTGAATACCGACGCCGAAGGCCGCCTGGTACTGTGCGATGTGTTAACTTACGTTGAGCGTTTTGAGCCGGAAGCGG
TGATTGACGTGGCGACGCTGACCGGTGCCTGCGTGATCGCGCTAGGCCATCACATTACCGGTCTGATGGCGAACCATAAC
CCACTGGCCCATGAACTGATTGCCGCGTCTGAACAATCCGGTGACCGTGCATGGCGCTTACCTCTGGGCGACGAGTACCA
GGAACAACTGGAGTCCAATTTTGCCGATATGGCGAACATTGGCGGTCGTCCTGGTGGGGCGATTACCGCAGGTTGCTTCC
TGTCGCGCTTTACCCGTAAGTATAACTGGGCGCACCTGGATATCGCCGGTACTGCCTGGCGTTCTGGTAAGGCGAAAGGC
GCAACCGGTCGCCCGGTGGCGTTGCTGGCACAGTTCCTGCTAAACCGCGCCGGGTTTAACGGCGAAGAGTAA

Protein sequence :
MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGK
ERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFN
VPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMKELGMHSYLAVG
QGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVL
AGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMANHN
PLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKG
ATGRPVALLAQFLLNRAGFNGEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00295 YP_008207760.1 Leucyl aminopeptidase Not tested AbaR25 Protein 2e-90 55
BJAB0868_00299 YP_008211625.1 Leucyl aminopeptidase Not tested AbaR26 Protein 2e-90 55