Gene Information

Name : papA_2 (c5188)
Accession : NP_757036.1
Strain : Escherichia coli CFT073
Genome accession: NC_004431
Putative virulence/resistance : Virulence
Product : PapA protein
Function : -
COG functional category : N : Cell motility
COG ID : COG3539
EC number : -
Position : 4948203 - 4948799 bp
Length : 597 bp
Strand : -
Note : Residues 12 to 198 of 198 are 99.46 pct identical to residues 1 to 187 of 187 from SwissProt.40 : >sp|P04740|FMK1_ECOLI KS71A FIMBRILLIN PRECURSOR (P-FIMBRIAL ANTIGEN)

DNA sequence :
GTGTGTTCAGTAATGAAAAAGAGGTTGTTATTTATGATTAAGTCGGTTATTGCCGGTGCGGTAGCTATGGCAGTGGTGTC
TTTTGGTGCAAATGCAGCTGCATCTATCCCTCAAGGACAAGGTGAAGTAAGTTTTAAAGGGACTGTTGTTGACGCTCCGT
GTGGTATTGAAACTCAGTCTGCAAAACAGGAAATTGATTTTGGTCAGATCTCTAAATCCTTCCTGCAAGAGGGGGGAGAG
ACTCAACCGAAAGATTTGAATATTAAGCTTGTGAATTGTGACATTACTAATTTCAAACAGCTTCAAGGCGGGGCAGCTAA
AAAAGGTACAGTGTCATTGACATTTTCAGGTGTGCCTGCAGAAAATGCAGATGACATGCTGCAAACAGTTGGAGATACTA
ATACTGCGATTGTTGTTACTGATTCGAGTGGAAAACGGGTGAAATTTGATGGAGCCACTGAGACCGGGGCTTCAAATCTG
ATTAATGGCGATAATACAATTCATTTTACTGCATTTGTTAAGAAAGATAATAGTGGCAAGAATGTAGCTGAAGGTGCCTT
CTCAGCAGTTGCGAATTTCAACCTGACTTATCAGTAA

Protein sequence :
MCSVMKKRLLFMIKSVIAGAVAMAVVSFGANAAASIPQGQGEVSFKGTVVDAPCGIETQSAKQEIDFGQISKSFLQEGGE
TQPKDLNIKLVNCDITNFKQLQGGAAKKGTVSLTFSGVPAENADDMLQTVGDTNTAIVVTDSSGKRVKFDGATETGASNL
INGDNTIHFTAFVKKDNSGKNVAEGAFSAVANFNLTYQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
papA_2 NP_757036.1 PapA protein Virulence PAI II CFT073 Protein 3e-86 100
papA AAL67417.1 PapA Virulence PAI II CFT073 Protein 3e-84 100
papA NP_755467.1 PapA protein Virulence PAI I CFT073 Protein 2e-65 78
prfA CAD42031.1 PrfA protein Virulence PAI II 536 Protein 7e-60 74
papA YP_002414017.1 P-fimbriae major subunit Not tested Not named Protein 6e-56 72
papA AAZ04426.1 major fibrial protein Virulence PAI I APEC-O1 Protein 6e-53 65
papA YP_854256.1 major fibrial protein Virulence PAI I APEC-O1 Protein 8e-53 65
pixA CAE85161.1 PixA protein Not tested PAI V 536 Protein 3e-37 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
papA_2 NP_757036.1 PapA protein VFG0893 Protein 9e-87 100
papA_2 NP_757036.1 PapA protein VFG0882 Protein 5e-66 78
papA_2 NP_757036.1 PapA protein VFG1550 Protein 3e-60 74