Gene Information

Name : actP (c5062)
Accession : NP_756914.1
Strain : Escherichia coli CFT073
Genome accession: NC_004431
Putative virulence/resistance : Resistance
Product : acetate permease
Function : -
COG functional category : R : General function prediction only
COG ID : COG4147
EC number : -
Position : 4836344 - 4837993 bp
Length : 1650 bp
Strand : -
Note : member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake

DNA sequence :
ATGAAAAGAGTTCTGACGGCGCTTGCCGCCACACTCCCTTTCGCAGCTAACGCCGCGGATGCTATTAGCGGGGCCGTAGA
GCGTCAGCCAACGAACTGGCAGGCGATTATTATGTTCCTGATTTTCGTCGTGTTTACGCTCGGCATTACCTACTGGGCGT
CAAAACGCGTACGTTCGCGTAATGACTACTACACCGCAGGCGGCAATATCACCGGTTTTCAGAACGGGCTGGCGATTGCC
GGGGACTATATGTCCGCCGCCTCATTCTTGGGGATCTCCGCGCTGGTGTTTACCTCCGGCTATGACGGCTTAATTTACTC
GCTAGGCTTCCTGGTAGGCTGGCCGATCATTTTGTTCCTGATTGCCGAACGTCTGCGTAACCTCGGTCGCTACACCTTTG
CCGATGTGGCCTCTTACCGTCTGAAACAAGGGCCGATTCGTATTCTTTCGGCCTGTGGTTCTCTGGTGGTGGTGGCGCTT
TACCTTATCGCCCAGATGGTGGGCGCAGGTAAACTGATCGAGCTGCTGTTTGGCCTTAACTATCACATTGCGGTAGTGCT
GGTCGGCGTGCTGATGATGATGTACGTCCTGTTCGGCGGCATGCTGGCGACCACCTGGGTACAAATTATTAAAGCCGTGC
TGTTGCTGTTCGGTGCCAGCTTTATGGCCTTTATGGTGATGAAACACGTCGGCTTTAGCTTCAACAATCTGTTCAGCGAA
GCGATGGCGGTACACCCGAAAGGTGTCGACATCATGAAGCCGGGCGGGCTGGTGAAAGATCCTATCTCCGCGCTCTCTTT
GGGGCTAGGACTGATGTTTGGTACGGCGGGCTTGCCGCATATTCTGATGCACTTCTTTACGGTCAGCGATGCCCGCGAAG
CACGTAAGAGCGTGTTCTACGCCACCGGATTTATGGGCTACTTCTACATCCTGACCTTTATTATCGGCTTTGGCGCGATC
ATGCTGGTCGGTGCGAATCCGGAATATAAAGACGCGGCGGGCCATCTGATTGGTGGTAACAACATGGCAGCAGTTCACCT
GGCCAATGCGGTGGGCGGCAACCTGTTCCTCGGCTTTATTTCAGCGGTTGCTTTCGCCACCATTCTTGCGGTGGTTGCGG
GTCTGACGCTGGCGGGCGCATCGGCGGTGTCTCACGACCTGTACGCTAACGTCTTCAAAAAAGGTGCGACCGAACGTGAA
GAGCTGCGGGTATCGAAAATCACCGTACTGATCCTCGGTGTGATTGCCATTATCCTCGGCGTGCTGTTTGAGAATCAGAA
CATCGCCTTTATGGTGGGGCTGGCGTTTGCCATCGCGGCGAGCTGTAACTTCCCGATCATTCTGCTTTCCATGTACTGGT
CGAAACTGACTACCCGTGGCGCAATGCTGGGCGGCTGGTTAGGACTGATTACTGCGGTGGTGCTGATGATCCTCGGCCCG
ACTATTTGGGTACAGATCCTCGGTCACGAAAAAGCCATCTTCCCGTATGAATACCCGGCGCTGTTCTCTATCAGCGTGGC
ATTCCTCGGTATCTGGTTATTCTCGGCAACGGATAATTCAGCGGAAGGTGCGCGCGAGCGTGAACTGTTCCGTGCGCAGT
TTATCCGTTCCCAGACTGGCTTTGGCGTTGAGCAGGGCCGCGCGCATTAA

Protein sequence :
MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKRVRSRNDYYTAGGNITGFQNGLAIA
GDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVAL
YLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFSE
AMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTAGLPHILMHFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAI
MLVGANPEYKDAAGHLIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVFKKGATERE
ELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGAMLGGWLGLITAVVLMILGP
TIWVQILGHEKAIFPYEYPALFSISVAFLGIWLFSATDNSAEGARERELFRAQFIRSQTGFGVEQGRAH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAK01502.1 putative amino acid transport protein Not tested PAGI-1 Protein 2e-122 58
cur_1523 YP_001800917.1 transporter Not tested Not named Protein 3e-66 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
actP NP_756914.1 acetate permease BAC0564 Protein 0.0 99
actP NP_756914.1 acetate permease BAC0570 Protein 2e-134 65