Gene Information

Name : dnaB (c5026)
Accession : NP_756878.1
Strain : Escherichia coli CFT073
Genome accession: NC_004431
Putative virulence/resistance : Unknown
Product : replicative DNA helicase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0305
EC number : 3.6.1.-
Position : 4802013 - 4803464 bp
Length : 1452 bp
Strand : +
Note : unwinds double stranded DNA

DNA sequence :
TTGTCCCCCATTCAACAGCAGGTAACACCATTCGTTATGGCAGGCAATAGACCTTTCAACAAACAACAGACTGATAACCG
CGAACGCGATCCACAAGTTGCCGGGCTAAAAGTGCCTCCGCACTCGATCGAAGCGGAGCAGTCGGTGTTGGGCGGTTTAA
TGCTGGATAACGAACGCTGGGATGATGTAGCCGAGCGTGTGGTGGCAGACGATTTTTACACCCGCCCACACCGTCATATC
TTTACTGAAATGGCGCGTTTGCAGGAAAGCGGTAGTCCTATCGATCTGATTACCCTTGCGGAATCGCTGGAACGCCAGGG
GCAACTCGATAGCGTCGGTGGTTTTGCTTATCTGGCAGAGCTGTCAAAAAATACGCCAAGTGCGGCGAACATCAGTGCAT
ATGCGGATATCGTGCGCGAACGTGCCGTTGTTCGTGAGATGATCTCCGTTGCTAACGAGATTGCCGAAGCTGGTTTTGAT
CCACAAGGGCGTACCAGTGAAGATCTGCTCGACCTTGCTGAATCCCGCGTCTTTAAAATTGCCGAAAGTCGTGCAAACAA
AGACGAAGGGCCGAAGAACATCGCCGATGTGCTCGACGCAACCGTGGCGCGTATTGAGCAGTTGTTTCAGCAGCCACACG
ATGGCGTTACCGGGGTAAATACCGGTTATGACGATCTCAACAAAAAAACCGCTGGCTTGCAGCCGTCGGATTTGATCATC
GTCGCCGCGCGTCCGTCGATGGGTAAAACAACATTTGCGATGAATCTCGTCGAAAACGCAGCGATGTTGCAGGATAAACC
GGTGCTTATCTTTTCGCTGGAGATGCCATCAGAACAGATTATGATGCGTTCTCTGGCGTCGCTGTCGCGCGTTGACCAGA
CTAAAATCCGTACCGGGCAGCTCGATGATGAAGACTGGGCACGCATTTCCGGCACCATGGGTATTTTGCTCGAAAAACGC
AATATCTATATCGATGATTCCTCCGGCTTGACGCCAACGGAGGTGCGTTCCCGCGCACGCCGTATTGCCCGTGAACACGG
CGGCATCGGGCTTATCATGATCGACTACCTGCAACTGATGCGCGTACCGGCGCTTTCCGATAACCGTACGCTGGAAATTG
CAGAAATCTCCCGCTCGCTGAAAGCACTGGCGAAAGAACTGAACGTGCCGGTGGTGGCGCTGTCCCAGTTGAACCGTTCT
CTGGAACAACGTGCCGACAAACGCCCGGTCAACTCCGACCTGCGTGAATCTGGCTCTATCGAGCAGGATGCGGACTTGAT
CATGTTTATCTATCGTGATGAGGTGTATCACGAAAACAGTGATTTAAAAGGCATCGCGGAAATTATTATCGGTAAACAAC
GTAACGGCCCAATCGGGACGGTACGCCTGACCTTTAACGGTCAATGGTCGCGCTTCGACAACTATGCGGGGCCGCAGTAC
GACGACGAATAA

Protein sequence :
MSPIQQQVTPFVMAGNRPFNKQQTDNRERDPQVAGLKVPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHI
FTEMARLQESGSPIDLITLAESLERQGQLDSVGGFAYLAELSKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFD
PQGRTSEDLLDLAESRVFKIAESRANKDEGPKNIADVLDATVARIEQLFQQPHDGVTGVNTGYDDLNKKTAGLQPSDLII
VAARPSMGKTTFAMNLVENAAMLQDKPVLIFSLEMPSEQIMMRSLASLSRVDQTKIRTGQLDDEDWARISGTMGILLEKR
NIYIDDSSGLTPTEVRSRARRIAREHGGIGLIMIDYLQLMRVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRS
LEQRADKRPVNSDLRESGSIEQDADLIMFIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNYAGPQY
DDE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
PMI2640 YP_002152342.1 DNA helicase Not tested Not named Protein 4e-106 55
dnaB2 YP_001402701.1 replicative DNA helicase Not tested YAPI Protein 3e-106 53
api2 CAF28476.1 putative DNA binding protein with DNA-dependent ATPase activity Not tested YAPI Protein 9e-107 53
dnaB2 YP_001007676.1 putative DNA helicase Not tested YAPI Protein 2e-106 53
dnaB CAI36044.1 replicative DNA helicase DnaB Not tested PPHGI-1 Protein 8e-88 50
unnamed ABR13456.1 replicative DNA helicase Not tested PAGI-5 Protein 9e-101 50
STY4522 NP_458617.1 DNA helicase Not tested SPI-7 Protein 1e-91 50
t4227 NP_807829.1 DNA helicase Not tested SPI-7 Protein 1e-91 50
dnaB1 YP_005176258.1 replicative DNA helicase Not tested ICEPmu1 Protein 8e-83 45