Gene Information

Name : thiC (c4951)
Accession : NP_756805.1
Strain : Escherichia coli CFT073
Genome accession: NC_004431
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 4725411 - 4727318 bp
Length : 1908 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
TTGGAACGAGCTATGTCTGCAACAAAACTGACCCGCCGCGAACAACGCGCCCAGGCCCAACATTTTATCGATACCCTGGA
AGGCTCCGCCTTTCCCAACTCAAAACGCATTTACATCACTGCCACACAACCCGGCGTGCGCGTGCCGATGCGTGAGATCC
AGCTTAGCCCGACGCTAATCGGCGGTAGCAAAGAACAACCGCAGTACGAAGAAAACGAAGCGATTCCGGTCTACGACACC
TCCGGTCCGTATGGCGATCCGCAGATCGCCATTAACGTGCAGCAAGGGCTGGCAAAACTACGCCAGCCGTGGATCGATGC
GCGCGGCGATACCGAAGAACTTACCGTGCGCAGTTCCGATTACACAAAAGCGCGGCTGGCAGATGATGGCCTCGACGAGC
TGCGTTTTAGCGGCGTATTAACGCCAAAACGCGCCAAAGCAGGACGCCGCGTCACCCAACTGCACTACGCCCGCCAGGGT
ATCATCACACCCGAAATGGAATTCATCGCCATTCGCGAGAATATGGGTCGCGAGCGCATACGGAGCGAAGTTTTACGCCA
CCAGCATCCGGGAATGAGCTTTGGCGCACGTCTGCCGGAAAATATCACTGCGGAATTTGTCCGTGATGAAGTTGCTGCCG
GACGTGCGATTATCCCGGCCAACATTAATCATCCGGAATCGGAGCCGATGATTATTGGCCGTAACTTCCTGGTAAAAGTT
AACGCCAATATCGGCAACTCAGCGGTCACTTCTTCCATCGAAGAAGAAGTGGAAAAACTGGTATGGTCCACACGCTGGGG
AGCGGATACCGTGATGGATCTTTCCACTGGTCGCTATATTCACGAAACCCGCGAGTGGATTTTGCGTAACAGCCCGGTGC
CGATCGGTACAGTGCCGATCTACCAGGCACTGGAGAAGGTGAACGGGATCGCTGAAGATCTTACCTGGGAAGTCTTCCGC
GACACCCTGCTGGAACAAGCCGAGCAAGGTGTGGATTACTTCACGATCCATGCGGGGGTGCTGCTGCGCTACGTGCCGAT
GACCGCGAAACGCCTGACCGGTATCGTCTCTCGCGGCGGTTCGATTATGGCGAAATGGTGCCTCTCCCATCATCAGGAAA
ATTTCCTCTATCAACACTTCCGCGAAATTTGTGAAATCTGTGCTGCTTATGACGTTTCGCTATCGCTGGGCGACGGCCTG
CGCCCCGGTTCTATTCAGGACGCCAACGATGAAGCACAGTTTGCCGAGCTGCATACGCTGGGTGAACTGACTAAAATCGC
CTGGGAATATGACGTACAGGTGATGATTGAAGGCCCAGGCCACGTGCCGATGCAGATGATTCGCCGCAATATGACCGAGG
AGTTAGAGCACTGCCACGAAGCGCCATTTTACACTCTGGGGCCGCTAACTACCGATATCGCGCCGGGCTATGACCACTTC
ACGTCAGGGATTGGCGCGGCGATGATTGGCTGGTTTGGTTGTGCAATGCTCTGCTACGTAACGCCGAAAGAGCATCTGGG
CCTGCCAAATAAAGAAGATGTTAAACAGGGGCTTATCACCTATAAGATTGCCGCTCACGCCGCCGACCTGGCGAAAGGGC
ATCCGGGCGCGCAAATTCGCGATAACGCCATGTCGAAAGCCCGCTTCGAATTTCGCTGGGAAGACCAGTTTAATCTGGCC
CTCGACCCGTTTACTGCCCGCGCTTATCACGATGAAACCCTGCCGCAAGAGTCCGGTAAAGTCGCCCATTTTTGCTCCAT
GTGTGGACCGAAATTCTGCTCGATGAAAATCAGCCAGGAAGTGCGTGATTACGCCGCCGCGCAAACCATTGAAGTGGGAA
TGGCGGATATGTCGGAGAACTTCCGCGCCAGAGGCGGAGAAATCTACCTGCGTAAGGAGGAAGCGTGA

Protein sequence :
MERAMSATKLTRREQRAQAQHFIDTLEGSAFPNSKRIYITATQPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDT
SGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQG
IITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKV
NANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEVFR
DTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGL
RPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHF
TSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLA
LDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMADMSENFRARGGEIYLRKEEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 69
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 69
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 68