Gene Information

Name : metB (c4892)
Accession : NP_756746.1
Strain : Escherichia coli CFT073
Genome accession: NC_004431
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 4648128 - 4649402 bp
Length : 1275 bp
Strand : +
Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine

DNA sequence :
TTGCTCAATCTATACGCAAAGAAGTTTAGATGTCCAGATGTATTGACGTCCATTAACACAATGTTTACTCTGGTGCCTGA
CATTTCACCGACCAAGCCCAGGGAACTTCATCACATGACGCGTAAACAGGCCACCATCGCAGTGCGTAGCGGGTTAAATG
ACGACGAACAGTATGGTTGCGTTGTCCCTCCCATCCATCTTTCCAGTACCTATAACTTTACCGGATTTAATGAACCGCGC
GCGCATGATTACTCGCGGCGCGGCAACCCAACGCGCGATGTGGTTCAGCGAGCGCTGGCAGAACTGGAAGGCGGTGCTGG
TGCAGTACTTACTAATACCGGCATGTCCGCGATTCACCTGGTAACGACCGTCTTTTTGAAACCTGGCGATCTGCTGGTTG
CGCCGCACGACTGCTACGGCGGTAGCTATCGCCTGTTCGACAGCCTGGCGAAACGCGGTTGCTATCGCGTGTTGTTTGTT
GATCAAAGCGATGAACAGGCATTACGGGCAGCGCTGGCAGAAAACCCCAAACTGGTACTGGTAGAAAGCCCAAGTAATCC
ATTGTTACGCGTCGTGGATATTGCGAAAATCTGCCATCTGGCAAGGGAAGTCGGGGCGGTGAGCGTGGTGGATAACACCT
TCTTAAGCCCGGCATTACAAAATCCACTGGCATTAGGTGCCGATCTGGTGTTGCATTCATGCACGAAATATCTGAACGGT
CACTCTGACGTGGTGGCAGGCGTAGTGATTGCTAAAGACCCGGACGTTGTCACTGAACTTGCCTGGTGGGCAAACAATAT
TGGCGTGACGGGCGGCGCGTTTGACAGCTATCTGCTGCTACGCGGGTTGCGAACGCTGGTGCCGCGTATGGAGCTGGCGC
AGCGCAACGCGCAGGCGATTGTGAAATATCTGCAAACCCAGCCGTTGGTGAAAAAACTGTATCACCCGTCGCTGCCGGAA
AATCAGGGGCATGAAATTGCCGCGCGCCAGCAAAAAGGCTTTGGCGCAATGTTGAGTTTTGAACTGGATGGCGATGAGCA
GACGCTGCGTCGTTTCCTGGGCGGGCTGTCGTTGTTTACGCTGGCGGAATCATTAGGGGGAGTGGAAAGTTTAATCTCTC
ACGCCGCAACCATGACACATGCAGGCATGGCGCCAGAAGCGCGTGCTGCCGCCGGGATCTCCGAGACGCTGCTGCGTATC
TCCACCGGTATTGAAGATGGCGAAGATTTAATTGCCGACCTGGAAAATGGCTTCCGGGCTGCAAACAAGGGGTAA

Protein sequence :
MLNLYAKKFRCPDVLTSINTMFTLVPDISPTKPRELHHMTRKQATIAVRSGLNDDEQYGCVVPPIHLSSTYNFTGFNEPR
AHDYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAIHLVTTVFLKPGDLLVAPHDCYGGSYRLFDSLAKRGCYRVLFV
DQSDEQALRAALAENPKLVLVESPSNPLLRVVDIAKICHLAREVGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNG
HSDVVAGVVIAKDPDVVTELAWWANNIGVTGGAFDSYLLLRGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLYHPSLPE
NQGHEIAARQQKGFGAMLSFELDGDEQTLRRFLGGLSLFTLAESLGGVESLISHAATMTHAGMAPEARAAAGISETLLRI
STGIEDGEDLIADLENGFRAANKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-58 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-59 43