Gene Information

Name : c4759 (c4759)
Accession : NP_756618.1
Strain : Escherichia coli CFT073
Genome accession: NC_004431
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 4524133 - 4526130 bp
Length : 1998 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGAATTCACAATTACTGGCTAACGCCATCCGGATGTTAAGTGTTGATGCGATCCAGAAAGCGAACTCCGGTCATCCGGG
CGCGCCGATGGGGATGGCGGATATTGCCGAAGTGGTCTGGCGTCGTCACCTGCGTCATAACCCAAAAAATCCGCAGTGGT
TTAACCGCGACCGCTATGTTCAGTCGAACGGGCACGGTTCCATGTTGATTTACGCTTTGCTGCATCTTACAGGCTACGAC
CTGTCGATGGATGATATTCGCGACTTTCGTCAGCTCCACTCCCGCACGCCAGGTCATCCAGAATATGGTTATACGCCGGG
TGTTGAAACCACCACCGGCCCGTTGGGGCAGGGCGTAGCTAATGCGGTGGGGATGGCGATTGCGGAGAAGGCGCTGGCGG
CAGAATTTAACAAACCGGGCTTTAATATTGTTGATCATCACACATGGCTATTTTTGGGTGATGGCTGCCTGATGGAAGGG
ATCTCCCACGAGGCCTGTGGTCTTGCAGGAACGCTGAAGCTCGGCAATCTGATTGCTATCTGGGACGATAACGGTATTTC
GATCGATGGTCACGTAGAAGGCTGGTTTGCTGAAGATACGGCTGCCCGTTTTCGTGCCTACGGCTGGCATGTCATTGAAG
GCGTTGATGGTCACGATCCAGAAGAGGTAGATGCTGCGGTGCGTGAAGCGAAAAGCGTCACGGATAAGCCCAGTCTGCTG
TGCTGCAAAACGATTATCGGTTTTGGTTCGCCAAATAAAGCCAACAGCCACGATTGCCACGGCTCGGCGCTGGGTGCAGA
TGAAGTGGCGCTGGTGCGTGAACGTCTGCAATGGCCGTATGCCCCTTTCGAAATTCCTGGTGAAATTTATGCCGCATGGG
ATGCGACCGAGAAAGGCGCGCAGGTTCAACAGGAATGGGATGCACTGTTTGCCGACTACGCGAAGCAGTGGCCGGAACTG
GCGGCGGAGTTTACTCGTCGCATGAAGGGTGATTTGCCTGCTGGCTGGGTCGAGAATATGCAGAAATATGTGCACGATCT
GCAATCCCATCCGGCGGCGCTGGCAACCCGTCAGGTTAGCCAGAAATGCCTCAATCACTTCGCAGATATGCTGCCGGAAC
TGATGGGCGGCTCGGCGGACTTGTCGCCCTCTAACCTGACTCGCCATCAGAAATCGGTTGATTTCACCGGAGAAAATCCG
GCGGGGAATTACATCTCCTATGGCGTGCGTGAATTTGGTATGTCGGCCATCATGAACGGTCTTGCGCTGCATGGTGGGTT
TATCCCTTACGGCGGTACTTTCCTGATGTTTATGGAATATGCGCGTAATGCACTGCGTATGGCGGCGCTGATGAAGATCC
GCTCGGTGTTTGTTTATACCCACGATACCATCGGCCTGGGCGAAGACGGCCCGACACATCAGCCCGTTGAGCAACTGGCG
TCGCTGCGTCTGACGCCGAATATGGAAACCTGGCGCGGTTGCGATCAGGTGGAAGTGGCGGTGGCCTGGCAACAGGCGAT
TGAGCGCAAAGATGGCCCAACGTCGTTGGTATTAACGCGCCAACCTCTGGCGCAACAGCCGCGCACCGCTGCACAGTTGG
CAGAGATTGCGCGTGGTGGTTATGTACTGAGTGATTGTGACGGTCAGCCTGAGATGATCCTCATTTCTGCGGGTTCAGAG
ATTGAGTTAGTGGTCAGCGCCGCAAAAGCGTTAACGGAAGAAGGGCGTAAAGTTCGCGTGGTTTCCCTGCCGTGTACCGA
GCGTTTCGATAATCAGGATGCGGCGTACAAAGAGTCGGTATTGCCAAAAGCTGTACGCAAACGTCTGGCGGTAGAAGCCA
GCATCGCCGGATTCTGGGAACGCTACGTGGGCCTGAACGGTAAAGTGATCGGCATGACGAGCTTTGGTGAGTCTGCTCCG
GCGAATGTGTTGTTCAAACACTTTGGTTTTACGCCGGAAAATGTCCTGGCGCAGGCGCGTGAGCTACTGAACAGCTAA

Protein sequence :
MNSQLLANAIRMLSVDAIQKANSGHPGAPMGMADIAEVVWRRHLRHNPKNPQWFNRDRYVQSNGHGSMLIYALLHLTGYD
LSMDDIRDFRQLHSRTPGHPEYGYTPGVETTTGPLGQGVANAVGMAIAEKALAAEFNKPGFNIVDHHTWLFLGDGCLMEG
ISHEACGLAGTLKLGNLIAIWDDNGISIDGHVEGWFAEDTAARFRAYGWHVIEGVDGHDPEEVDAAVREAKSVTDKPSLL
CCKTIIGFGSPNKANSHDCHGSALGADEVALVRERLQWPYAPFEIPGEIYAAWDATEKGAQVQQEWDALFADYAKQWPEL
AAEFTRRMKGDLPAGWVENMQKYVHDLQSHPAALATRQVSQKCLNHFADMLPELMGGSADLSPSNLTRHQKSVDFTGENP
AGNYISYGVREFGMSAIMNGLALHGGFIPYGGTFLMFMEYARNALRMAALMKIRSVFVYTHDTIGLGEDGPTHQPVEQLA
SLRLTPNMETWRGCDQVEVAVAWQQAIERKDGPTSLVLTRQPLAQQPRTAAQLAEIARGGYVLSDCDGQPEMILISAGSE
IELVVSAAKALTEEGRKVRVVSLPCTERFDNQDAAYKESVLPKAVRKRLAVEASIAGFWERYVGLNGKVIGMTSFGESAP
ANVLFKHFGFTPENVLAQARELLNS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 99
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 69