Gene Information

Name : c4492 (c4492)
Accession : NP_756354.1
Strain : Escherichia coli CFT073
Genome accession: NC_004431
Putative virulence/resistance : Virulence
Product : ShiA-like protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4276297 - 4277340 bp
Length : 1044 bp
Strand : +
Note : Residues 1 to 347 of 347 are 96.82 pct identical to residues 1 to 347 of 347 from GenPept.129 : >gb|AAD44731.1|AF141323_2 (AF141323) ShiA [Shigella flexneri]

DNA sequence :
ATGAACGATAGATTATGCTTTGAAGTGCACGATAACCAGGGTTATTTCGTATTTCCGGATACCTGGTTTGGCCCATTGCT
GGGGGAGTTTGAAGAAGTGCTTGATGCATACGACGCTGATGAAATCAGCGAGACGAGTTACATCAACAAACTCCGACGCC
TTGCTCAACGGGAGCCGGACTTTATTGATATACACGCTCATCTGGCATATGCATTTCTGGAACAGAATGCCCCGCGTAAG
GCACTGAACGCCGCTCTTAAAGGACTGGCGGCAGGTAATCGTATCATCCCGGAAAGTTTCTGTGGTGAAATAATCTGGAT
GCATCCCGAAAACCGGCCTTATCTGCGCGCGCTTTATGCAGCAATTCTCGCAAATGTGCACTTACAGCGCCATCAGGATG
CGGTTATGCTCACTGATAAAATACTGGCATACAATCCTGAAGATAATCAGGGGGCTCGCTGGTTGTTGGGTTCAGAGCTG
TTACGCACCGGCGATCATGAGCGAGCCTTCAGTGTACTGAAAGAGCATGCTGATGAATTTTCACCTTACTGGTATGAACT
CGGTCTCCTGCATTTTCTGAACGGGGAACATGTTAAGGCCGCCACAGCTTTTCGCCATGGCTTTGCCACAAACACTTACA
TCGCAGAAATGCTGTGCGGAAATCTGCATCCATTTCCACTTGCTGTGTGGCATGACTTCTCCGGCTCTCTGGATACGGCA
GAAGATTACTATGCAACATACTCACCATTATGGGGACAATATCCGGAAGCATTGCTGTTTGTAAACTGGCTCTATAATCA
TTCCTCTGTGCTGCATGAACGGGCAGAAATCATTAAATGCGCCGAAATGCTGATGCAGGAAGATGATTTCGAAATATGCG
AAAGTATTTTAAGACAGCAGGAGAAGTTGCGTGAAAGAATTGATGAGACGCTTTCTGAGAAAATTGTACAGAAATGCAGA
AATATGAATGGTGAATATGTCTGGCCCTGGATATTGCCGTTTTCAGCGGCAGGCATGAAACATACTGGCATACAGTATCA
GTAG

Protein sequence :
MNDRLCFEVHDNQGYFVFPDTWFGPLLGEFEEVLDAYDADEISETSYINKLRRLAQREPDFIDIHAHLAYAFLEQNAPRK
ALNAALKGLAAGNRIIPESFCGEIIWMHPENRPYLRALYAAILANVHLQRHQDAVMLTDKILAYNPEDNQGARWLLGSEL
LRTGDHERAFSVLKEHADEFSPYWYELGLLHFLNGEHVKAATAFRHGFATNTYIAEMLCGNLHPFPLAVWHDFSGSLDTA
EDYYATYSPLWGQYPEALLFVNWLYNHSSVLHERAEIIKCAEMLMQEDDFEICESILRQQEKLRERIDETLSEKIVQKCR
NMNGEYVWPWILPFSAAGMKHTGIQYQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aec34 AAW51717.1 Aec34 Not tested AGI-3 Protein 1e-154 99
shiA NP_839237.1 hypothetical protein Virulence SHI-2 Protein 4e-151 97
shiA NP_709438.1 hypothetical protein Virulence SHI-2 Protein 4e-151 97
shiA AAD44731.1 ShiA Virulence SHI-2 Protein 3e-151 97
shiA AFX83956.1 ShiA family protein Not tested SE-PAI Protein 4e-141 91
c3557 NP_755432.1 ShiA-like protein Not tested PAI I CFT073 Protein 9e-138 87
ECUMN_3323 YP_002414005.1 SHI-2 pathogenicity island protein Virulence Not named Protein 7e-139 87

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
c4492 NP_756354.1 ShiA-like protein VFG0599 Protein 2e-151 97
c4492 NP_756354.1 ShiA-like protein VFG1694 Protein 4e-138 87