Gene Information

Name : ycbS (c4212)
Accession : NP_756076.1
Strain : Escherichia coli CFT073
Genome accession: NC_004431
Putative virulence/resistance : Virulence
Product : outer membrane usher protein ycbS
Function : -
COG functional category : N : Cell motility
COG ID : COG3188
EC number : -
Position : 3995436 - 3998030 bp
Length : 2595 bp
Strand : -
Note : Escherichia coli K-12 ortholog: b0940; Escherichia coli O157:H7 ortholog: z5915

DNA sequence :
ATGAACCTAAAGCTCAAAAGATGCGAATATTGGATGGCGGCACAAAAGCAGATGAAACGGGTTGTGCCGCTTCTTCTGGT
TATTATGCCTGCATGTTCAATCGCGGGAATGCGCTTTAACCCTGCTTTTCTGTCGGGTGATACTGAAGCTGTTGCTGACT
TATCCCGCTTCGAGAAAGGGATGACTTATCTTCCTGGTAGCTATGAAGTCGAAGTTTGGGTCAATGATTCCCCTTTACTC
TCTCGTACTGTAACTTTTAAAGCAGACGATGAGAATCAACTGATTCCCTGCCTTTCACTTGCTGACTTATTAAGCCTTGG
AATTAACAAAAATGCGCTGCCAGAGCAGGCTTTGGCTTCATCTGAAAATAGTTGCCTTGATTTGCGTATCTGGTTTCCCG
ATGTGCATTACATGCCGGAGCTGGATGCACAGAGACTTAAACTGACCTTTCCACAGGCGATAATAAAACGTGACGCTCGC
GGATATATTCCACCAGAACAGTGGGATAACGGTATTACAGCTTTTTTGCTGAATTATGACTTTTCTGGTAATAACGATCG
TGGTGATTACTCTTCAAATAACTATTATTTAAATCTTCGCGCTGGGATCAATATTGGTGCATGGCGTTTTCGCGATTATT
CAACCTGGAGTCGTGGGAGTAATTCAGCAGGTAAACTGGAGCATATCAGTAGTACGTTGCAGCGCGTTATTATTCCTTTC
AGAAGTGAATTAACGCTAGGAGATACATGGTCATCATCAGATGTTTTCGACAGTGTTAGTATTCGTGGCATAAAACTGGA
ATCTGACGAAAATATGTTGCCCGATAGTCAAAGTGGTTTCGCTCCCACGGTGCGCGGAATTGCGAAAAGTCGCGCTCAGG
TAACAATCAAACAGAATGGTTATGTCATTTATCAAACCTATATGCCGCCGGGACCGTTTGAGATTAGCGATCTTAACCCG
ACATCATCTGCGGGAGATCTGGAAGTTACCATCAAAGAGTCTGATAATTCAGAAACTGTCTATACCGTACCTTATGCCGC
TGTCCCCATCCTGCAACGAGAAGGTCATTTAAAATATTCTACTACGGTTGGCCAATATCGAAGCAATAGCTATAACCAGA
AAAGTCCTTATGTATTTCAGGGGGAATTAATTTGGGGTTTACCCTGGGATATTACGGCTTATGGTGGGGCACAATTCTCT
GAGGATTACCGGGCGTTGGCGCTCGGCCTTGGCCTGAATCTGGGTGTATTTGGTGCAACATCGTTTGATGTTACTCAGGC
TAACAGTTCGCTTGTGGATGGGAGCAAACATCAAGGGCAATCTTATCGTTTTCTTTATTCCAAATCGTTAGTTCAGACAG
GAACAGCATTCCATATTATTGGCTATCGTTATTCAACCCAGGGCTTTTACACTTTAAGTGATACGACATACCAACAAATG
TCAGGGACTGTTGTTGATCCAAAAACGTTAGATGATAAAGATTACGTTTATAACTGGAATGATTTTTATAACTTGCGTTA
TAGCAAACGTGGAAAATTTCAGGCTAGTGTATCGCAACCTTTCGGTAACTACGGGTCTATGTATTTATCGGCTAGTCAGC
AAACATACTGGAATACTGATAAAAAAGATTCTTTATACCAAGTTGGTTATAACACCAGTATTAAGGGTATCTATCTAAAT
GTTGCGTGGAATTACAGTAAATCACCAGGGACAAATGCGGATAAAATTGTCTCGCTAAATGTCTCATTACCTATAAGTAA
TTGGTTATCTTCCACGAATGATGGGCGCTCATCATCGAATGCCATGACTGCAACGTATGGTTATAGTCAGGATAACCACG
GACAGGTAAACCAATATACGGGGGTATCTGGTTCTCTGTTGGAGCAGCATAATCTCAGTTATAACATACAACATGGTTTT
GCTAATCAGGATAATAGCAGTAGTGGTTCTGTTGGTGTTAATTATCGTGGGGCATATGGTTCCTTGAATTCCGCCTACAG
TTACGATAATGAAGGTAATCAACAAATAAACTATGGCATCAGTGGTGCTCTTGTTGTACATGAAAATGGTCTTACGTTGA
GTCAACCATTAGGTGAAACTAATGTTTTGATAAAAGCGCCTGGAGCGAATAATGTGGATGTTCAGCGGGGGACAGGAATA
TCCACTGACTGGCGTGGATATGCAGTTGTTCCTTATGCAACAGAATATAGACGTAATAATATTTCATTAGATCCTATGTC
AATGAATATGCATACTGAACTGGATATCACTTCCACTGAAGTTATTCCGGGAAAAGGTGCGTTAGTTCGTGCAGAGTTTG
CTGCTCATATCGGTATTCGTGGTTTGTTCACAGTTCGTTATCGTAATAAATCAGTCCCATTCGGTGCTACAGCCAGCGCT
CAGATTAAAAACAGTAGTCAAATTACCGGGATTGTCGGCGATAATGGACAACTTTATCTCTCAGGATTGCCTTTAGAAGG
TGTTATTAATATCCAGTGGGGAGACGGTGTTCAGCAAAAATGTCAGGCTAATTACAAGCTCCCTGAAACAGAACTGGATA
ATCCTGTTAGCTATGCAACTCTGGAGTGCCGCTAA

Protein sequence :
MNLKLKRCEYWMAAQKQMKRVVPLLLVIMPACSIAGMRFNPAFLSGDTEAVADLSRFEKGMTYLPGSYEVEVWVNDSPLL
SRTVTFKADDENQLIPCLSLADLLSLGINKNALPEQALASSENSCLDLRIWFPDVHYMPELDAQRLKLTFPQAIIKRDAR
GYIPPEQWDNGITAFLLNYDFSGNNDRGDYSSNNYYLNLRAGINIGAWRFRDYSTWSRGSNSAGKLEHISSTLQRVIIPF
RSELTLGDTWSSSDVFDSVSIRGIKLESDENMLPDSQSGFAPTVRGIAKSRAQVTIKQNGYVIYQTYMPPGPFEISDLNP
TSSAGDLEVTIKESDNSETVYTVPYAAVPILQREGHLKYSTTVGQYRSNSYNQKSPYVFQGELIWGLPWDITAYGGAQFS
EDYRALALGLGLNLGVFGATSFDVTQANSSLVDGSKHQGQSYRFLYSKSLVQTGTAFHIIGYRYSTQGFYTLSDTTYQQM
SGTVVDPKTLDDKDYVYNWNDFYNLRYSKRGKFQASVSQPFGNYGSMYLSASQQTYWNTDKKDSLYQVGYNTSIKGIYLN
VAWNYSKSPGTNADKIVSLNVSLPISNWLSSTNDGRSSSNAMTATYGYSQDNHGQVNQYTGVSGSLLEQHNLSYNIQHGF
ANQDNSSSGSVGVNYRGAYGSLNSAYSYDNEGNQQINYGISGALVVHENGLTLSQPLGETNVLIKAPGANNVDVQRGTGI
STDWRGYAVVPYATEYRRNNISLDPMSMNMHTELDITSTEVIPGKGALVRAEFAAHIGIRGLFTVRYRNKSVPFGATASA
QIKNSSQITGIVGDNGQLYLSGLPLEGVINIQWGDGVQQKCQANYKLPETELDNPVSYATLECR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
fim2D AFH78429.1 putative fimbrial usher protein Virulence KpGI-5 Protein 2e-171 46
sfaF CAC16953.2 SfaF protein Virulence PAI III 536 Protein 3e-171 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ycbS NP_756076.1 outer membrane usher protein ycbS VFG0446 Protein 2e-173 47
ycbS NP_756076.1 outer membrane usher protein ycbS VFG0876 Protein 3e-180 46
ycbS NP_756076.1 outer membrane usher protein ycbS VFG1645 Protein 2e-171 44
ycbS NP_756076.1 outer membrane usher protein ycbS VFG0912 Protein 5e-171 44
ycbS NP_756076.1 outer membrane usher protein ycbS VFG0454 Protein 1e-162 43