Gene Information

Name : c3774 (c3774)
Accession : NP_755645.1
Strain : Escherichia coli CFT073
Genome accession: NC_004431
Putative virulence/resistance : Virulence
Product : ferric enterobactin transport ATP-binding protein fepC
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1120
EC number : -
Position : 3606907 - 3607716 bp
Length : 810 bp
Strand : -
Note : Escherichia coli K-12 ortholog: b0588; Escherichia coli O157:H7 ortholog: z4385

DNA sequence : 
GTGGCACATAACGCAAAAGGGCAGGGGCTGATCCTCGACAATGTTTCTGCCGGGTATCACAAGAAGATCATTGTTGATGG
TGTTTCTTTCTCCGTTCCCACAGAAAAAATGACCGTTCTGGTTGGGGCAAACGGCTGTGGAAAGTCGACGTTGCTCAGCA
CCATTGCACGTATCTTGCAACCTATGGGCGGTTCGATATTGCTTGATGGCAAAGCGATTCACGAGCAACCAACGAAAGCG
TTATCCCGTAGACTTGGGATCTTGCCGCAGTCGCCATTATTGCCGGAGGGCTTAACCGTTTATGAACTGGTGTCGCGTGG
GCGTTTTCCCTGGCAAAATTTCATACGTCAATGGAGCGACGCCGATGAGCAGGCGGTGGAAGATGCCCTGAAATTAACCG
GTACGCAGGAGTTTGCACATTTACCTGTTGAAAAACTCTCTGGTGGGCAGCGCCAGCGTTGCTGGATTGCGATGGTGTTG
GCGCAAAAGACGCCTTATATCCTGCTGGATGAACCCACAACCTGGCTTGATTTACGTTATCAGGTTGAAATTCTTGAGTT
ATTACATGATTTAACGCGTCATCACGGGCGTACAGTCGTCGTGGTGTTGCATGATCTGAATTTTGCCGTCAATTATGGCG
ATACGTTGATATTTTTACGCCAGGGGAAAGTGGTGCGTGTGTTGAATGAGGGGGAGCATTGCACGCCTGAACTGGTAAAA
GCGGTCTTTGACGTTGATGTTCACGCATCAATAAATCCTCTGACGGGAAAGCCGTTCTTCATGCCGTTTCGTGGTGTAGA
AAAAGTATGA

Protein sequence : 
MAHNAKGQGLILDNVSAGYHKKIIVDGVSFSVPTEKMTVLVGANGCGKSTLLSTIARILQPMGGSILLDGKAIHEQPTKA
LSRRLGILPQSPLLPEGLTVYELVSRGRFPWQNFIRQWSDADEQAVEDALKLTGTQEFAHLPVEKLSGGQRQRCWIAMVL
AQKTPYILLDEPTTWLDLRYQVEILELLHDLTRHHGRTVVVVLHDLNFAVNYGDTLIFLRQGKVVRVLNEGEHCTPELVK
AVFDVDVHASINPLTGKPFFMPFRGVEKV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
fagC YP_005680307.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 4e-50 46
fagC YP_003782430.1 ABC transporter ATP-binding protein Not tested PiCp 1 Protein 4e-50 46
fagC YP_005682397.1 ATP binding cytoplasmic membrane protein Virulence PiCp 1 Protein 4e-50 46
fagC YP_005684488.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 4e-50 46
iusE YP_005143742.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 6e-52 45
fecE AAL08451.1 ATP-binding protein FecE Virulence SRL Protein 1e-44 44
SPN23F_09560 YP_002510939.1 ferric siderophore ABC transporter ATP-binding protein Virulence PPI-1 Protein 2e-52 41
SP_1035 NP_345510.1 iron-compound ABC transporter ATP-binding protein Not tested PPI-1 Protein 2e-52 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
c3774 NP_755645.1 ferric enterobactin transport ATP-binding protein fepC BAC0164 Protein 7e-45 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
c3774 NP_755645.1 ferric enterobactin transport ATP-binding protein fepC VFG1042 Protein 6e-45 44
c3774 NP_755645.1 ferric enterobactin transport ATP-binding protein fepC VFG0925 Protein 1e-50 44