Gene Information

Name : nrdF (c3229)
Accession : NP_755111.1
Strain : Escherichia coli CFT073
Genome accession: NC_004431
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 3084039 - 3084998 bp
Length : 960 bp
Strand : +
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGAAACTCTCACGTATCAGCGCCATCAACTGGAACAAGATATCTGACGATAAAGATCTGGAGGTGTGGAATCGCCTGAC
CAGCAATTTCTGGCTACCAGAAAAGGTGCCACTGTCGAACGATATTCCTGCATGGCAGACATTAAGTGTCGTAGAACAAC
AACTAACAATGCGCGTTTTTACTGGCCTGACGCTGCTCGACACGCTGCAAAATGTTATCGGCGCGCCCTCGCTGATGCCC
GATGCACTCACCCCCCATGAAGAGGCGATATTATCAAATATCAGCTTTATGGAAGCGGTTCATGCCCGCTCTTACAGTTC
AATTTTCTCGACGCTGTGCCAGACCAAAGATGTCGATGCCGCCTACGCCTGGAGTGAAGAAAACGCGCCGTTGCAGCGAA
AAGCACAGATTATTCAGCAACATTATCGCGGTGATGATCCGCTGAAAAAGAAAATCGCCAGTGTGTTTCTTGAATCTTTT
TTGTTCTATTCCGGTTTCTGGCTGCCGATGTATTTTTCCAGCCGCGGAAAGCTAACCAATACCGCAGACCTGATCCGTCT
GATTATCCGGGATGAAGCAGTCCACGGTTACTACATCGGCTATAAATATCAGAAAAACCTGGAAAAGATCTCCCAGGCAC
GACGTGAAGAATTGAAGAGTTTCGCCTTCGATTTGTTGCTGGAACTCTATGACAACGAGTTGCAATACACCGATGAGCTG
TACGCCGAAACCCCGTGGGCTGACGATGTGACAGCGTTTCTCTGTTACAACGCCAATAAGGCGTTGATGAATCTGGGCTA
CGAACCACTATTTCCCGCAGGAATGGCGGAAGTGAATCCGGCAATCCTCGCCGCGCTTTCGCCGAATGCCGATGAAAATC
ACGATTTCTTTTCCGGTTCAGGCTCTTCATATGTGATGGGAAAAGCGGTCGAAACAGAAGATGAGGACTGGAATTTCTGA

Protein sequence :
MKLSRISAINWNKISDDKDLEVWNRLTSNFWLPEKVPLSNDIPAWQTLSVVEQQLTMRVFTGLTLLDTLQNVIGAPSLMP
DALTPHEEAILSNISFMEAVHARSYSSIFSTLCQTKDVDAAYAWSEENAPLQRKAQIIQQHYRGDDPLKKKIASVFLESF
LFYSGFWLPMYFSSRGKLTNTADLIRLIIRDEAVHGYYIGYKYQKNLEKISQARREELKSFAFDLLLELYDNELQYTDEL
YAETPWADDVTAFLCYNANKALMNLGYEPLFPAGMAEVNPAILAALSPNADENHDFFSGSGSSYVMGKAVETEDEDWNF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 8e-105 67