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Name : c2586 (c2586) Accession : NP_754474.2 Strain : Escherichia coli CFT073 Genome accession: NC_004431 Putative virulence/resistance : Unknown Product : tyrosine kinase Function : - COG functional category : M : Cell wall/membrane/envelope biogenesis COG ID : COG3206 EC number : 2.7.10.2 Position : 2421027 - 2423189 bp Length : 2163 bp Strand : - Note : Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide) DNA sequence : ATGACAGAAAAAGTAAAACAACATGCCGCTCCGGTAACGGGCAGTGATGAAATCGATATTGGTCGCCTGGTCGGCACCGT CATTGAAGCGCGCTGGTGGGTGATTGGCATCACCGCTGTATTTGCCCTCTGTTCCGTGGTTTACACTTTCTTCGCCACGC CGATTTATAGTGCCGACGCACTGGTACAAATCGAGCAAAACAGTGGCAATTCGTTAGTGCAGGACATTGGTTCGGCATTA GCCAACAAACCGCCAGCATCGGACGCCGAGATCCAGTTGATTCGTTCGCGTCTGGTGCTTGGTAAAACGGTGGACGATCT CGACCTCGATATTGCGGTGAGCAAAAACACGTTCCCGATTTTCGGTGCGGGCTGGGATCGCCTGATGGGACGTCAGAACG AGACGGTGAAAGTGACCACCTTTAACCGCCCGAAAGAGATGGCGGATCGGGTGTTTACGCTTAATGTGCTTGATGACAAA AACTACACCCTGAGCAGTGATGGCGGCTTTAGCGCCCGTGGGCAAGCGGGCCAGATGCTGAAAAAAGAAGGCGTCACGCT GATGGTTGAAGCTATTCACGCCAGCCCGGGGAGTGAGTTTACCGTCACCAAATACTTCACGCTGGGGATGATCAACCAAC TGCAAAACAGCCTGACGGTAACGGAGAACGGCAAAGACGCAGGCGTACTGAGCTTGACTTATACCGGTGAAGATCGCGAA CAGATCCGCGACATTCTTAACAGCATCGCCCGTAACTATCAGGAGCAAAATATTGAGCGCAAATCGGCGGAAGCGTCGAA AAGCCTCGCCTTCCTCGCGCAACAGTTACCGGAAGTACGTAGCCGCCTTGATGTTGCCGAAAACAAACTGAATGCCTTCC GTCAGGATAAAGATTCTGTTGATCTGCCGCTGGAAGCGAAAGCGGTGCTCGATTCGATGGTGAACATCGACGCGCAGTTG AACGAACTGACCTTTAAAGAGGCGGAAATCTCCAAGCTGTACACCAAAGTTCATCCGGCGTACCGCACGCTGCTGGAGAA ACGGCAGGCGCTGGAAGACGAAAAAGCCAAACTTAATGGTCGCGTAACGGCGATGCCGAAAACCCAGCAGGAAATTGTCC GTCTGACCCGCGATGTCGAGTCTGGGCAGCAGGTCTATATGCAACTGCTGAATAAAGAACAGGAGCTGAAAATCACCGAA GCCAGCACCGTCGGCGATGTGCGCATTGTTGACCCGGCAATCACCCAGCCTGGCGTGCTAAAACCGAAGAAAGGGCTGAT TATCCTCGGGGCGATTATCCTTGGCCTGATGCTCTCTATCGTGGGTGTGCTGCTGCGCTCGTTGTTTAATCGCGGCATCG AAAGCCCGCAGGTGCTGGAAGAACACGGTATCAGTGTCTATGCCAGCATCCCGCTGTCGGAGTGGCAGAAAGCGCGCGAT AGCGTCAAAACCATCAAAGGGATTAAACGCTATAAACAGAGCCAGCTACTGGCGGTGGGGAATCCAACCGATCTGGCGAT TGAAGCCATCCGCAGTCTGCGTACCAGTTTGCACTTCGCGATGATGCAGGCACAGAACAATGTGTTGATGATGACCGGGG TTAGCCCGTCAATCGGTAAAACCTTTGTCTGCGCCAACCTGGCGGCGGTGATTAGCCAGACCAATAAACGGGTGTTGTTG ATCGACTGCGATATGCGCAAAGGTTACACCCACGAGCTGTTGGGCACTAATAACGTTAATGGCCTGTCGGAAATTCTGAT TGGACAGGGCGATATTACTACCGCGGCTAAACCGACCTCTATTGCCAAATTTGACCTGATCCCGCGCGGTCAGGTACCGC CAAATCCTTCTGAACTGTTGATGAGCGAACGCTTTGCCGAACTGGTGAACTGGGCGAGTAAAAACTACGACCTGGTGTTG ATTGATACGCCGCCGATTCTGGCAGTGACCGATGCGGCAATTGTTGGTCGTCATGTCGGAACCACGTTAATGGTGGCGCG TTATGCGGTCAACACATTGAAAGAAGTGGAAACCAGTCTGAGCCGCTTTGAGCAAAACGGTATTCCGGTGAAAGGGGTGA TTCTGAACTCCATCTTCCGCCGCGCCAGCGCGTATCAGGATTATGGCTATTACGAATACGAATATAAGTCGGATGCGAAA TAA Protein sequence : MTEKVKQHAAPVTGSDEIDIGRLVGTVIEARWWVIGITAVFALCSVVYTFFATPIYSADALVQIEQNSGNSLVQDIGSAL ANKPPASDAEIQLIRSRLVLGKTVDDLDLDIAVSKNTFPIFGAGWDRLMGRQNETVKVTTFNRPKEMADRVFTLNVLDDK NYTLSSDGGFSARGQAGQMLKKEGVTLMVEAIHASPGSEFTVTKYFTLGMINQLQNSLTVTENGKDAGVLSLTYTGEDRE QIRDILNSIARNYQEQNIERKSAEASKSLAFLAQQLPEVRSRLDVAENKLNAFRQDKDSVDLPLEAKAVLDSMVNIDAQL NELTFKEAEISKLYTKVHPAYRTLLEKRQALEDEKAKLNGRVTAMPKTQQEIVRLTRDVESGQQVYMQLLNKEQELKITE ASTVGDVRIVDPAITQPGVLKPKKGLIILGAIILGLMLSIVGVLLRSLFNRGIESPQVLEEHGISVYASIPLSEWQKARD SVKTIKGIKRYKQSQLLAVGNPTDLAIEAIRSLRTSLHFAMMQAQNNVLMMTGVSPSIGKTFVCANLAAVISQTNKRVLL IDCDMRKGYTHELLGTNNVNGLSEILIGQGDITTAAKPTSIAKFDLIPRGQVPPNPSELLMSERFAELVNWASKNYDLVL IDTPPILAVTDAAIVGRHVGTTLMVARYAVNTLKEVETSLSRFEQNGIPVKGVILNSIFRRASAYQDYGYYEYEYKSDAK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| orf41 | AAO18066.1 | Orf41 | Not tested | TTSS locus | Protein | 6e-155 | 48 |
