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Name : c2433 (c2433) Accession : NP_754325.1 Strain : Escherichia coli CFT073 Genome accession: NC_004431 Putative virulence/resistance : Virulence Product : 2,3-dihydroxybenzoate-AMP ligase Function : - COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism COG ID : COG1021 EC number : - Position : 2245422 - 2246669 bp Length : 1248 bp Strand : + Note : Enterochelin synthase E; Escherichia coli K-12 ortholog: b0594; Escherichia coli O157:H7 ortholog: z0736; bifunctional; Enterobactin synthetase component E; S-dihydroxybenzoyltransferase DNA sequence : ATGAATTCTTCCTTTGAATCTCTGATTGAACAGTATCCCTTACCCATTGCCGAACAGTTGCGCCACTGGGCGGCCCGTTA TGCCTCGCGAATTGCCGTCGTTGATGCAAAGGGGTCGTTAACCTACAGCGCGCTTGATGCACAAGTTGACGAACTTGCCG CAGGTCTGTCATCACTGGGTTTGCGTTCGGGGGAGCATGTAATTGTGCAGCTTCCCAACGACAACGCGTTTGTTACCCTG CTGTTCGCCTTGTTAAGACTGGGCGTTATCCCCGTGCTGGCGATGCCCTCGCAACGGGCGCTGGATATCGACGCGCTGAT TGAGCTGGCGCAACCCGTCGCTTACGTTATTCACGGGGAAAACCACGCAGAGCTGGCCCGACAGATGGCGCACAAACACG CCTGCTTGCGTCATGTTCTGGTCGCTGGAGAGACCGTGAGCGACGATTTTACGCCGCTCTTCTCCCTTCACGGTGAGCGA CAGGCATGGCCGCAGCCTGATGTTTCCGCCACCGCGTTGTTGTTGCTCTCAGGCGGCACAACCGGCACGCCCAAACTCAT CCCGCGCCGACATGCCGACTATAGCTATAACTTCAGCGCTTCTGCTGAACTGTGCGGCATCAGCCAACAGAGCGTGTATC TCGCCGTCCTCCCGGTGGCGCATAACTTTCCGCTGGCCTGCCCCGGTATTCTGGGAACGCTTGCCTGCGGCGGAAAAGTG GTGCTGACCGACAGCGCCAGCTGTGATGAGGTGATGCCTTTAATCGCGCAGGAAAGAGTGACTCACGTCGCCCTGGTTCC GGCGCTGGCGCAATTATGGGTGCAGGCCAGGGAGTGGGAAGACAGCGACCTTTCGTCGCTGCGCGTCATTCAGGCAGGCG GCGCCCGGCTCGACCCGACGCTTGCTGAGCAGGTTATCGCCACCTTTGACTGTACCCTGCAACAGGTTTTCGGTATGGCG GAAGGCCTGCTCTGTTTTACCCGGCTGGACGATCCGCATGCCACCATTCTCCACAGCCAGGGGCGCCCGTTGTCCCCTCT GGATGAAATCCGCATCGTTGATCAAGACGAGAACGACGTCGCGCCGGGCGAAACCGGGCAATTGTTAACGCGCGGCCCTT ATACCATTTCGGGCTATTACCGCGCCCCTGCCCACAATGCGCAGGCCTTTACCGCGCAAGGGTTTTACCGCACAGGCGAC AATGTCAGGCTGGATGAGGTGGGGAACCTGCACGTTGAGGACGCATAA Protein sequence : MNSSFESLIEQYPLPIAEQLRHWAARYASRIAVVDAKGSLTYSALDAQVDELAAGLSSLGLRSGEHVIVQLPNDNAFVTL LFALLRLGVIPVLAMPSQRALDIDALIELAQPVAYVIHGENHAELARQMAHKHACLRHVLVAGETVSDDFTPLFSLHGER QAWPQPDVSATALLLLSGGTTGTPKLIPRRHADYSYNFSASAELCGISQQSVYLAVLPVAHNFPLACPGILGTLACGGKV VLTDSASCDEVMPLIAQERVTHVALVPALAQLWVQAREWEDSDLSSLRVIQAGGARLDPTLAEQVIATFDCTLQQVFGMA EGLLCFTRLDDPHATILHSQGRPLSPLDEIRIVDQDENDVAPGETGQLLTRGPYTISGYYRAPAHNAQAFTAQGFYRTGD NVRLDEVGNLHVEDA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| ybtE | YP_853079.1 | yersiniabactin siderophore biosynthetic protein | Virulence | PAI IV APEC-O1 | Protein | 2e-179 | 99 |
| irp5 | YP_002346898.1 | yersiniabactin siderophore biosynthetic protein | Virulence | HPI | Protein | 2e-179 | 99 |
| ybtE | NP_669710.1 | salicyl-AMP ligase | Virulence | HPI | Protein | 2e-179 | 99 |
| ybtE | NP_993003.1 | yersiniabactin siderophore biosynthetic protein | Virulence | HPI | Protein | 2e-179 | 99 |
| ybtE | YP_070120.1 | yersiniabactin siderophore biosynthetic protein | Virulence | HPI | Protein | 2e-179 | 99 |
| ybtE | CAA21394.1 | - | Virulence | HPI | Protein | 2e-179 | 99 |
| ybtE | AAA93464.1 | yersiniabactin 2,3-dihydoxybenzoate-AMP ligase | Virulence | HPI | Protein | 1e-179 | 99 |
| irp5 | CAA73130.1 | Irp5 protein | Virulence | HPI | Protein | 3e-176 | 98 |
| irp5 | YP_001006819.1 | yersiniabactin siderophore biosynthetic protein | Virulence | HPI | Protein | 5e-176 | 98 |
| irp2E | YP_005163485.1 | siderophore biosynthetic protein | Virulence | Not named | Protein | 1e-57 | 42 |
| irp2E | YP_005134497.1 | siderophore biosynthetic protein | Virulence | Not named | Protein | 1e-57 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| c2433 | NP_754325.1 | 2,3-dihydroxybenzoate-AMP ligase | VFG0168 | Protein | 3e-82 | 50 |
| c2433 | NP_754325.1 | 2,3-dihydroxybenzoate-AMP ligase | VFG1817 | Protein | 1e-71 | 45 |
| c2433 | NP_754325.1 | 2,3-dihydroxybenzoate-AMP ligase | VFG0932 | Protein | 7e-59 | 41 |
