Gene Information

Name : c2421 (c2421)
Accession : NP_754313.1
Strain : Escherichia coli CFT073
Genome accession: NC_004431
Putative virulence/resistance : Virulence
Product : ABC transporter
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1132
EC number : -
Position : 2222220 - 2224049 bp
Length : 1830 bp
Strand : -
Note : Similar to YbtQ [Yersinia pestis] and Irp7 [Yersinia enterocolitica]; Residues 10 to 609 of 609 are 99.50 pct identical to residues 1 to 600 of 600 from GenPept.129 : >emb|CAC90730.1| (AJ414150) inner membrane ABC-transporter YbtQ [Yersinia pestis]

DNA sequence :
GTGGAACACAGGAAGAGGTGGTGGAAAATGAAAGACAATAATCCTGCGGATAACCTGGCCTGGCGCGTCATCTGGCGCCA
GCTTATCTCCAGCGTTGGCAGTCAGGCCAGGATGCTGCGACGCAGTATGCTGGCGCTGTTGCTGGCGGCATTCATGCAGG
GGATCGCCTTTGCCTGTCTTTATCCGATCATTGATGCGCTGTTACGGGGAGACGCGCCGCAACTTCTTAACTGGGCTATG
GCCTTCAGCGTCGCCGCAATTGTGACGCTGGTGCTACGCTGGTATGGCCTGGGCTTTGAATACCGTGGTCATCTGGCGCA
GGCTACCCATGAGTTGCGCCTGCGACTTGGCGAGCAGTTACGCCGCGTGCCGCTGGAGAAGCTCCAGCGCGGCAGGGCGG
GTGAAATGAACGCCTTGCTGCTGGGCAGCGTGGATGAAAACCTCAATTATGTTATTGCGATAGCCAATATTTTGCTGCTC
ACCATTGTCACGCCGCTGACGGCGTCGCTGGCGACATTGTGGATAGACTGGCGGCTGGGGCTGGTGATGTTGCTGATCTT
CCCTCTGCTGGTGCCGTTTTATTACTGGCGCCGCCCGGCGATGCGGCGACAAATGCAGACGCTGGGGGAAGCGCACCAGC
GTCTGAGCGGCGATATCGTTGAATTTGCTCAGGGGATGATGGTATTGCGCACCTGCGGCAGCGATGCCGATAAAAGCCGG
GCGCTGCTGGCGCATTTCAATGCGCTGGAAAACTTACAGACCCGCACTCACCGTCAGGGCGCTGGCGCGACGATGCTGAT
CGCCAGCGTCGTGGAGTTGGGCCTACAGGTGGTGGTGTTATCCGGGATCGTCTGGGTAGTGACGGGCACTCTGAACCTCG
CCTTTTTGATTGCCGCCGTCGCGATGATTATGCGCTTCGCAGAACCGATGGCGATGTTTATCAGCTACACCTCGGTTGTG
GAACTGATCGCCAGCGCCCTGCAACGGATTGAGCAGTTTATGGCGATAGCACCGCTTCCCGTCGCAGAGCAAAGCGAGAT
GCCGGAACGTTACGATATCCGCTTTGACAACGTCAGCTATCGCTACGAAGAAGGTGACGGCCACGCGCTTAATCATGTTT
CTTTGACGTTCCCGGCAGCCAGTATGAGCGCGCTGGTGGGTGCCTCCGGCGCAGGCAAAACTACGGTCACCAAACTGTTA
ATGCGCTATGCCGATCCGCAGCAAGGGCAGATTTCTATTGGCGGCGTCGATATTCGCCGCCTGACGCCGGAACAGCTCAA
TAGCCTGATTTCTGTTGTTTTCCAGGATGTCTGGCTGTTTGATGACACGCTGCTGGCGAATATCCGTATCGCGCGCCCAC
AGGCGACGCGGCAGGAGGTAGAAGAGGCCGCCCGCGCGGCGCAGTGCCTTGAGTTTATTTCCCGTCTTCCGCAAGGCTGG
CTGACGCCAATGGGAGAGATGGGCGGCCAGCTATCGGGCGGCGAGCGCCAGCGGATTTCCATTGCCAGAGCGTTATTGAA
AAACGCGCCGGTCGTCATTCTCGATGAACCGACTGCCGCGCTGGATATTGAAAGCGAGCTGGCGGTGCAAAAAGCGATCG
ATAACCTGGTTTACAACCGGACGGTGATTATCATCGCTCACCGTTTATCCACCATCGCCGGGGCCGGAAACATTCTGGTG
ATGGAAGAGGGACAGGTGGTTGAGCAGGGTACTCATGCGCAATTGCTCTCACATCATGGGCGTTATCAGGCGCTGTGGCA
GGCGCAAATGGCCGCGCGCGTGTGGCGCGACGACGGGGGTTCCGCGTCTGGAGAGTGGGTGCATGAGTGA

Protein sequence :
MEHRKRWWKMKDNNPADNLAWRVIWRQLISSVGSQARMLRRSMLALLLAAFMQGIAFACLYPIIDALLRGDAPQLLNWAM
AFSVAAIVTLVLRWYGLGFEYRGHLAQATHELRLRLGEQLRRVPLEKLQRGRAGEMNALLLGSVDENLNYVIAIANILLL
TIVTPLTASLATLWIDWRLGLVMLLIFPLLVPFYYWRRPAMRRQMQTLGEAHQRLSGDIVEFAQGMMVLRTCGSDADKSR
ALLAHFNALENLQTRTHRQGAGATMLIASVVELGLQVVVLSGIVWVVTGTLNLAFLIAAVAMIMRFAEPMAMFISYTSVV
ELIASALQRIEQFMAIAPLPVAEQSEMPERYDIRFDNVSYRYEEGDGHALNHVSLTFPAASMSALVGASGAGKTTVTKLL
MRYADPQQGQISIGGVDIRRLTPEQLNSLISVVFQDVWLFDDTLLANIRIARPQATRQEVEEAARAAQCLEFISRLPQGW
LTPMGEMGGQLSGGERQRISIARALLKNAPVVILDEPTAALDIESELAVQKAIDNLVYNRTVIIIAHRLSTIAGAGNILV
MEEGQVVEQGTHAQLLSHHGRYQALWQAQMAARVWRDDGGSASGEWVHE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
APECO1_1055 YP_853072.1 ABC transporter Not tested PAI IV APEC-O1 Protein 0.0 99
irp7 CAB46572.1 inner membrane ABC-transporter, Irp7 Virulence HPI Protein 0.0 99
irp7 YP_001006812.1 inner membrane ABC-transporter YbtQ Not tested HPI Protein 0.0 99
irp7 YP_002346905.1 ABC transporter permease Not tested HPI Protein 0.0 99
ybtQ NP_669703.1 permease and ATP-binding protein of yersiniabactin-iron ABC transporter Virulence HPI Protein 0.0 99
ybtQ NP_993010.1 ABC transporter permease Virulence HPI Protein 0.0 99
ybtQ YP_070127.1 ABC transporter permease Virulence HPI Protein 0.0 99
ybtQ CAA21387.1 - Virulence HPI Protein 0.0 99

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
c2421 NP_754313.1 ABC transporter BAC0433 Protein 0.0 99