Gene Information

Name : c2420 (c2420)
Accession : NP_754312.1
Strain : Escherichia coli CFT073
Genome accession: NC_004431
Putative virulence/resistance : Virulence
Product : cytoplasmic transmembrane protein
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG2814
EC number : -
Position : 2220947 - 2222350 bp
Length : 1404 bp
Strand : -
Note : Similar to YbtX [Yersinia pestis] and Irp8 [Yersinia enterocolitica]; Residues 6 to 467 of 467 are 99.35 pct identical to residues 1 to 462 of 462 from GenPept.129 : >emb|CAA21386.1| (AL031866) ORF63,len=462 aa, transmembrane protein, similarity to Escher

DNA sequence :
TTGAGCAGGGTACTCATGCGCAATTGCTCTCACATCATGGGCGTTATCAGGCGCTGTGGCAGGCGCAAATGGCCGCGCGC
GTGTGGCGCGACGACGGGGGTTCCGCGTCTGGAGAGTGGGTGCATGAGTGATGTTCAGTCGAATGTGAAACCGCTGACGT
TGACGACCGGGCGGGTGATTTTTGCTATTGCCGGCGTCTATGTGACGCAGAGTCTGGTATCGGCGCTGTCTATGCAGTCC
TTACCCGCGCTGGTGCGCGCTGCTGGCGGTTCGCTGGCGCTTGCCGGTGCGACAACCCTGTTTATGCTGCCCTGGGCGCT
GAAGTTTATTTGGGCGCCGTGGATCGAGCGCTGGCGGCTTCCGCCCGGTAGCCAGGAACGCCGTTCCCGCATGTTAATCC
TGCGTGGTCAGGTCGCGCTAGCGGCGATCCTGACTATTGCCGCAGCGATTGGCTGGTTTGGGCGAGAAGGGGGATTCCCC
GATACGCAAATCGTCGCGTTATTTGTTCTGTTTATGGTGGCAGGCACGGTCGCCTCCACCATTGATATCGCCAGCGACGG
CTTTTGTGTCGATCAACTGACCCGCACGGGTTACGGCTGGGGAAACAGCGTGCAGGTCGGCGGCAGCTATCTGGGAATGA
TGTGCGGCGGCGGGGTGTTCCTGATGCTGTCGGCGGCATCCGGCTGGCCTGTCGCCATGCTGATGATGGCGGTGCTGATT
ATGGCGCTGTCACTCCCGCTGTGGCGCATTACGGAGCCGACGCGAACAGCGACTATCCCGCATGTTCCGGCGTTAGGTTA
TGCGCTAAGGAGGAAGCAGGCGCGCCTGGGCTTACTGCTGGTATTGATGCTGAATTCAGGCATGCGGTTTGTGCTGCCTC
TTCTGGCACCGCTGTTGTTGGATCATGGGTTGAGCATGTCCGCATTGGGCGCGCTGTTCAGCGGCGGCAATATTGCAGCG
GGCATAGCAGGAACGCTGGCTGGCGGATTGCTGATGAAATACACCTCACCCGGCAGAGCGCTGTTGACGGCTTATGGCGT
CCAGGGGATCGCGCTGCTGGCGGTGGTGATGACGCTCATGATGGCGCCGGGTCATCTGCTGCTGCAGATTCTCCAGTGTC
TGGTCATTGTCCAGTCCATTTCGCTGGCCTGCGCGCTGGTCTGTCTTTACGCCACGCTGATGTCGCTTTCATCGCCTTTG
CAGGCCGGTGTCGACTTCACCCTCTTTCAATGTACTGATGCGGCAATCGCCATTCTGGCAGGCGTTATCGGTGGCGTTGT
TGCTCAACATTTTGGCTATGCGGCCTGCTTCCTGTTTGCCGGGGCATTCACGTTGCTGGCGGCGTGGGTTGCTTATATCC
GGCTGCATTCGGCAAGAGAACTGATGACAAGCGCAATTGATTGA

Protein sequence :
MSRVLMRNCSHIMGVIRRCGRRKWPRACGATTGVPRLESGCMSDVQSNVKPLTLTTGRVIFAIAGVYVTQSLVSALSMQS
LPALVRAAGGSLALAGATTLFMLPWALKFIWAPWIERWRLPPGSQERRSRMLILRGQVALAAILTIAAAIGWFGREGGFP
DTQIVALFVLFMVAGTVASTIDIASDGFCVDQLTRTGYGWGNSVQVGGSYLGMMCGGGVFLMLSAASGWPVAMLMMAVLI
MALSLPLWRITEPTRTATIPHVPALGYALRRKQARLGLLLVLMLNSGMRFVLPLLAPLLLDHGLSMSALGALFSGGNIAA
GIAGTLAGGLLMKYTSPGRALLTAYGVQGIALLAVVMTLMMAPGHLLLQILQCLVIVQSISLACALVCLYATLMSLSSPL
QAGVDFTLFQCTDAAIAILAGVIGGVVAQHFGYAACFLFAGAFTLLAAWVAYIRLHSARELMTSAID

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp8 YP_002346906.1 signal transducer Not tested HPI Protein 2e-120 99
ybtX YP_070128.1 MFS superfamily transporter signal transducer Virulence HPI Protein 2e-120 99
ybtX CAA21386.1 - Virulence HPI Protein 9e-139 99
ybtX YP_853071.1 hypothetical protein Not tested PAI IV APEC-O1 Protein 1e-139 99
ybtX NP_669702.1 hypothetical protein Virulence HPI Protein 3e-141 99
ybtX NP_993011.1 signal transducer Virulence HPI Protein 3e-141 99
irp8 YP_001006811.1 putative signal transducer Not tested HPI Protein 2e-118 99
irp8 CAB46571.1 signal transducer, Irp8 Virulence HPI Protein 2e-135 98