Gene Information

Name : nadE (c2139)
Accession : NP_754033.1
Strain : Escherichia coli CFT073
Genome accession: NC_004431
Putative virulence/resistance : Unknown
Product : NAD synthetase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0171
EC number : 6.3.1.5
Position : 1976303 - 1977130 bp
Length : 828 bp
Strand : +
Note : catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli

DNA sequence :
ATGACATTGCAACAACAAATAATAAAGGCGCTGGGCGCAAAACCGCAGATTAATGCTGAAGAGGAAATTCGTCGTAGTAT
CGATTTTCTGAAAAGCTACCTGCAAACTTATCCGTTCATTAAATCACTGGTGCTCGGGATCAGCGGCGGTCAGGACTCCA
CGCTTGCCGGTAAGCTGTGCCAGATGGCGATTAATGAGCTGCGCCAGGAAACCGGCAACGAATCACTGCAATTTATTGCC
GTACGCCTGCCCTATGGTGTCCAGGCCGACGAACAAGATTGCCAGGATGCCATCGCCTTTATTCAACCGGATCGCGTATT
AACCGTTAATATCAAGGGCGCGGTACTCGCCAGCGAGCAGGCATTGCGGGAAGCAGGCATTGAACTGAGCGATTTTGTCC
GTGGCAATGAAAAAGCGCGTGAGCGGATGAAAGCACAATATAGCATTGCGGGTATGACCAGCGGTGTCGTGGTGGGCACC
GATCATGCTGCAGAAGCTATTACCGGATTCTTCACTAAATATGGTGACGGCGGTACGGACATTAATCCGCTGTATCGTCT
CAACAAACGTCAGGGTAAACAGTTACTGGCGGCATTAGGTTGCCCGGAACACCTTTATAAGAAAGCGCCAACGGCCGATC
TTGAAGATGATCGCCCTTCTCTGCCGGATGAAGTGGCACTCGGCGTGACCTATGACAATATCGACGACTATCTGGAAGGG
AAAAACGTACCTGAACAGGTCGCCAGAACAATAGAGAACTGGTATCTGAAAACCGAACATAAACGCCGTCCGCCAATTAC
CGTTTTCGATGATTTCTGGAAAAAGTAA

Protein sequence :
MTLQQQIIKALGAKPQINAEEEIRRSIDFLKSYLQTYPFIKSLVLGISGGQDSTLAGKLCQMAINELRQETGNESLQFIA
VRLPYGVQADEQDCQDAIAFIQPDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMKAQYSIAGMTSGVVVGT
DHAAEAITGFFTKYGDGGTDINPLYRLNKRQGKQLLAALGCPEHLYKKAPTADLEDDRPSLPDEVALGVTYDNIDDYLEG
KNVPEQVARTIENWYLKTEHKRRPPITVFDDFWKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nadE YP_001800880.1 NAD synthetase Not tested Not named Protein 9e-60 53