Gene Information

Name : c1934 (c1934)
Accession : NP_753830.1
Strain : Escherichia coli CFT073
Genome accession: NC_004431
Putative virulence/resistance : Virulence
Product : outer membrane usher protein fimD
Function : -
COG functional category : N : Cell motility
COG ID : COG3188
EC number : -
Position : 1774532 - 1777183 bp
Length : 2652 bp
Strand : -
Note : Escherichia coli K-12 ortholog: b4317; Escherichia coli O157:H7 ortholog: z2203

DNA sequence :
ATGACAGCCTTTCGTGCCGCATTTAAGGCATATCGTATGCATCAGGTGTTAATACTGCCTCGCTTTGCACGGCTTACCTT
TGCCCTTGGCTTAGCAACTGCGGTTTTTCCCGTTGACGCAGAGTATTATTTTAATCCACGGTTTTTAAGCAATGACCTTG
CTGAATCTGTCGATTTATCTGCCTTTACTAAGGGACGCGAGGCCCCACCTGGTACATATCGGGTCGACATTTATTTGAAC
GACGAATTTATGGCTAGTCGGGATATTACTTTTATTGCAGATGATAATAACGCAGATCTCATCCCATGCCTGAGTACAGA
CCTTCTTGTCAGTCTTGGCATAAAAAAATCAGCATTATTAGACAACAAGGAACATTCGGCAGATAAACATGTGCCGGACA
ACAGCGCATGCACACCACTTCAGGATCGTTTGGCTGACGCATCATCTGAGTTTGATGTTGGTCAGCAACATCTGTCACTC
TCCGTTCCGCAAATATATGTCGGCAGAATGGCTCGCGGCTATGTTTCTCCTGATCTGTGGGAAGAAGGAATAAATGCCGG
GCTACTAAACTATAGTTTTAATGGTAATTCTATTAATAACCGTAGTAACCATAATGCAGGAAAATCCAACTATGCATATT
TGAATTTACAGAGTGGCATCAACATTGGTAGTTGGCGACTGCGCGATAACTCAACGTGGAGTTATAACAGTGGGAGTAGC
AATTCATCTGACAGCAATAAATGGCAGCATATCAATACGTCGGCTGAACGTGACATTATTCCGTTACGCTCACGGTTAAC
AGTGGGTGATAGTTATACCGATGGCGATATTTTTGACAGTGTGAACTTTCGTGGCCTTAAAATAAATTCAACAGAAGCGA
TGTTGCCCGATAGCCAACATGGTTTCGCTCCGGTGATTCATGGTATTGCTCGTGGCACCGCACAAGTGAGTGTAAAACAG
AATGGATACGATGTTTATCAGACTACTGTCCCACCCGGCCCTTTTACTATTGATGATATCAACTCTGCGGCCAATGGTGG
TGATCTGCAAGTAACCATAAAAGAGGCAGACGGCAGTATTCAGACATTATATGTTCCTTATTCGTCTGTTCCGGTTCTCC
AACGTGCTGGATATACGCGTTATGCACTTGCCATGGGGGAATATCGTAGTGGAAATAACCTGCAAAGCACCCCCAAGTTC
GTACAAGCAAGCTTGATGCATGGTCTGAAAGGAAACTGGACACCTTATGGCGGAATGCAAATTGCAGAAGATTATCAGGC
CTTCAACCTTGGTATTGGTAAAGATTTAGGACTTTTTGGTGCCTTTTCTTTCGATATTACGCAGGCCAATACGACACTTG
CAGATGACACCCGTCACAGCGGACAATCGGTTAAATCCGTCTACAGCAAATCCTTCTACCAGACGGGAACCAATATCCAG
GTCGCAGGATATCGCTATTCTACGCAAGGTTTTTATAACTTATCCGACAGTGCATACAGTCGAATGAGTGGTTACACCGT
CAAGCCTCCTACCGGAGACACCAGTGAGCAGACACTATTTATTGATTATTTTAATCTGTTCTACAGTAAGCGTGGTCAGG
AACAAATAAGCATCTCTCAGCAGCTTGGAAATTACGGTACGACATTTTTCAGTGCCAGTCGCCAAAGTTACTGGAACACG
TCACGCAGCGACCAGCAAATATCATTTGGATTAAATGTGCCGTTTGGTGATATTACGACTTCGCTGAATTACAGCTATTC
CAATAATATATGGCAAAACGATCGGGATCATTTACTCGCTTTTACGCTTAATGTTCCCTTTAGTCATTGGATGCGTACAG
ATAGTCAGTCGGCATTTCATAATTCAAACGCCAGTTACAGTATGTCAAACGATTTGAAAGGCGGCATGACCAACCTATCA
GGGGTTTATGGCACTCTACTGCCGGATAATAACCTGAATTATAGTGTTCAGGTCGGTAACACCCACGGGGGTAATACATC
GTCTGGCACCAGTGGTTACAGTTCTCTTAATTATCGTGGAGCTTACGGTAATACGAATGTCGGTTACAGTCGGAGTGGTG
ACAGCAGCCAGATTTATTACGGAATGAGTGGTGGCATTATTGCTCATGCTGATGGCATCACCTTTGGACAGCCGCTGGGC
GACACAATGGTTCTGGTTAAGGCTCCTGGCGCTGATAATGTCAAAATAGAGAACCAGACCGGTATTCATACCGACTGGCG
TGGCTATGCCATATTACCATTTGCGACAGAATATAGAGAAAATCGTGTCGCTCTTAACGCGAATTCCCTTGCAGATAATG
TTGAACTGGATGAAACCGTGGTCACTGTCATCCCAACTCACGGTGCTATTGCCAGAGCAACATTTAATGTACAAATCGGC
GGGAAAGTATTAATGACGTTGAAGTACGGTAATAAGAGCGTTCCATTCGGTGCAATTGTCACACATGGAGAGAATAAAAA
TGGCAGCATTGTCGCGGAAAACGGTCAGGTTTATCTGACTGGACTTCCACAGTCAGGGAAATTACAGGTTTCATGGGGCA
AAGATAAAAACTCAAACTGTATTGTCGAGTACAAGCTTCCTGAAGTTTCTCCTGGTACCTTACTGAACCAGCAGACAGCA
ATCTGTCGCTAA

Protein sequence :
MTAFRAAFKAYRMHQVLILPRFARLTFALGLATAVFPVDAEYYFNPRFLSNDLAESVDLSAFTKGREAPPGTYRVDIYLN
DEFMASRDITFIADDNNADLIPCLSTDLLVSLGIKKSALLDNKEHSADKHVPDNSACTPLQDRLADASSEFDVGQQHLSL
SVPQIYVGRMARGYVSPDLWEEGINAGLLNYSFNGNSINNRSNHNAGKSNYAYLNLQSGINIGSWRLRDNSTWSYNSGSS
NSSDSNKWQHINTSAERDIIPLRSRLTVGDSYTDGDIFDSVNFRGLKINSTEAMLPDSQHGFAPVIHGIARGTAQVSVKQ
NGYDVYQTTVPPGPFTIDDINSAANGGDLQVTIKEADGSIQTLYVPYSSVPVLQRAGYTRYALAMGEYRSGNNLQSTPKF
VQASLMHGLKGNWTPYGGMQIAEDYQAFNLGIGKDLGLFGAFSFDITQANTTLADDTRHSGQSVKSVYSKSFYQTGTNIQ
VAGYRYSTQGFYNLSDSAYSRMSGYTVKPPTGDTSEQTLFIDYFNLFYSKRGQEQISISQQLGNYGTTFFSASRQSYWNT
SRSDQQISFGLNVPFGDITTSLNYSYSNNIWQNDRDHLLAFTLNVPFSHWMRTDSQSAFHNSNASYSMSNDLKGGMTNLS
GVYGTLLPDNNLNYSVQVGNTHGGNTSSGTSGYSSLNYRGAYGNTNVGYSRSGDSSQIYYGMSGGIIAHADGITFGQPLG
DTMVLVKAPGADNVKIENQTGIHTDWRGYAILPFATEYRENRVALNANSLADNVELDETVVTVIPTHGAIARATFNVQIG
GKVLMTLKYGNKSVPFGAIVTHGENKNGSIVAENGQVYLTGLPQSGKLQVSWGKDKNSNCIVEYKLPEVSPGTLLNQQTA
ICR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
fim2D AFH78429.1 putative fimbrial usher protein Virulence KpGI-5 Protein 0.0 57
sfaF CAC16953.2 SfaF protein Virulence PAI III 536 Protein 0.0 54

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
c1934 NP_753830.1 outer membrane usher protein fimD VFG0876 Protein 0.0 58
c1934 NP_753830.1 outer membrane usher protein fimD VFG1645 Protein 0.0 54
c1934 NP_753830.1 outer membrane usher protein fimD VFG0912 Protein 0.0 54
c1934 NP_753830.1 outer membrane usher protein fimD VFG0446 Protein 4e-159 44