Gene Information

Name : umuC (c1632)
Accession : NP_753537.1
Strain : Escherichia coli CFT073
Genome accession: NC_004431
Putative virulence/resistance : Unknown
Product : DNA polymerase V subunit UmuC
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0389
EC number : 2.7.7.7
Position : 1468502 - 1469770 bp
Length : 1269 bp
Strand : +
Note : binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization

DNA sequence :
ATGTTTGCCCTCTGTGATGTAAACGCGTTTTATGCCAGCTGTGAGACGGTGTTTCGCCCTGATTTATGGGGTAAACCGGT
GGTTGTGCTATCGAATAATGACGGTTGCGTTATCGCCCGAAACGCTGAGGCAAAGGCGCTGGGCGTTAAAATGGGCGATC
CCTGGTTCAAACAAAAAGATCTGTTTCGTCGCTGTGGCGTGGTTTGCTTTAGCAGCAATTATGAGCTTTACGCAGACATG
AGTAATCGGGTGATGTCGACGCTGGAAGAACTATCGCCCCGCGTCGAGATTTACAGTATTGATGAGGCATTCTGCGATCT
GACAGGTGTGCATAATTGTCGCGATCTGACTGATTTTGGCAGAGAAATTCGCGCAACGGTGCTACAACGTACCCATCTTA
CTGTTGGTGTGGGGATCGCCCAGACCAAAACGCTGGCTAAGCTTGCCAATTATGCGGCAAAAAAATGGCAGCGGCAGACG
GGCGGGGTGGTGGATTTATCAAATCTGGAACGCCAGCGTAAATTAATGTCTGCTCTCCCCGTGGATGAAGTCTGGGGGAT
TGGACGGCGGATCAGCAAAAAACTGGACGCGATGGGGATCAAAACCGTTCTCGATTTGGCGGATTCAGATATCCGGTTTA
TCCGTAAACATTTTAATGTCGTGCTCGAAAGAACGGTGCGTGGACTGCGCGGTGAACCCTGTTTGCAACTGGAAGAGTTT
GCACCGACGAAGCAGGAAATTATCTGTTCCCGCTCGTTTGGTGAACGCATCACGGATTATCCGTCGATGCGGCAGGCCAT
TTGTAGTTACGCTGCCCGGGCGGCGGAAAAACTTCGCAGCGAGCATCAATATTGTCGGTTTATCTCCACGTTTATTAAGA
CGTCACCATTTGCGTTCAATGAACCTTATTACGGCAATAGCGCATCGGTAAAACTGCTGACGCCCACTCAGGACAGCAGG
GATATCATTAACGCCGCTACGCGATCTCTGGATGCCATCTGGCAAGCGGGCCATCGCTACCAAAAAGCGGGCGTGATGCT
GGGGGATTTCTTCAGTCAGGGAGTCGCGCAGCTCAATTTATTCGATGACAACGCACCGCGCCCCGGGAGTGAGCAATTGA
TGGCGGTAATGGATACGCTGAATGCTAAAGAGGGCAGAGGAACACTCTATTTTGCCGGGCAGGGGATCCAGCAACAATGG
CAGATGAAGCGTGCCATGCTTTCACCATGTTATACAACGCGAAGTTCTGATTTACTGCGGGTCAAATAA

Protein sequence :
MFALCDVNAFYASCETVFRPDLWGKPVVVLSNNDGCVIARNAEAKALGVKMGDPWFKQKDLFRRCGVVCFSSNYELYADM
SNRVMSTLEELSPRVEIYSIDEAFCDLTGVHNCRDLTDFGREIRATVLQRTHLTVGVGIAQTKTLAKLANYAAKKWQRQT
GGVVDLSNLERQRKLMSALPVDEVWGIGRRISKKLDAMGIKTVLDLADSDIRFIRKHFNVVLERTVRGLRGEPCLQLEEF
APTKQEIICSRSFGERITDYPSMRQAICSYAARAAEKLRSEHQYCRFISTFIKTSPFAFNEPYYGNSASVKLLTPTQDSR
DIINAATRSLDAIWQAGHRYQKAGVMLGDFFSQGVAQLNLFDDNAPRPGSEQLMAVMDTLNAKEGRGTLYFAGQGIQQQW
QMKRAMLSPCYTTRSSDLLRVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
samB NP_458681.1 UV protection protein Not tested SPI-7 Protein 2e-126 63
umuC NP_807889.1 DNA polymerase V subunit UmuC Not tested SPI-7 Protein 2e-126 63
rulB CAI36137.1 nucleotidyltransferase/DNA polymerase Not tested PPHGI-1 Protein 1e-89 50
unnamed ABR13403.1 DNA-directed DNA polymerase Not tested PAGI-5 Protein 2e-74 49