Gene Information

Name : sitA (c1600)
Accession : NP_753508.1
Strain : Escherichia coli CFT073
Genome accession: NC_004431
Putative virulence/resistance : Virulence
Product : SitA protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG0803
EC number : -
Position : 1449293 - 1450150 bp
Length : 858 bp
Strand : -
Note : Residues 2 to 263 of 285 are 62.97 pct identical to residues 3 to 257 of 293 from SwissProt.40 : >sp|Q57449|Y362_HAEIN PERIPLASMIC IRON-BINDING PROTEIN HI0362 PRECURSOR

DNA sequence : 
ATGCACTCGATAAAAAAAGTAACCATGCTCTTGGGGGGCCTCGCACTCACCTGCTCGATCGCATTTCAGGCAAGTGCAAC
TGAAAAATTCAAGGTCATTACAACATTTACCATCATCGCGGATATGGCCAAAAACGTGGCGGGAGATGCTGCAGAAGTCT
CATCCATAACCAAGCCTGGTGCAGAAATTCATGAGTATCAGCCTACCCCTGGCGATATTAAACGTGCGCAGGGGGCACAA
CTGATTCTCGCCAATGGTATGAATCTGGAATTGTGGTTCCAACGCTTTTACCAGCATCTCAATGGGGTTCCAGAAGTAAT
TGTCTCTTCGGGTGTGACGCCTGTAGGGATCACCGAAGGACCCTATGAGGGCAAACCTAACCCCCATGCATGGATGTCGC
CAGATAATGCTCTGATTTACGTCGATAATATTCGTGATGCGTTGATAAAATACGATCCGGCAAATGCACAAACCTACCAA
CGCAATGCCGATACTTATAAAGCCAAGATTACCCAAACCCTTGCCCCCCTGCGTAAGCAGATTACGGAACTCCCTGAGAA
TCAGCGATGGATGGTCACCAGTGAAGGGGCTTTTTCTTATCTCGCACGCGATTTGGGGCTAAAAGAGCTTTATCTGTGGC
CGATTAATGCCGATCAACAAGGAACACCGCAGCAGGTACGTAAGGTTGTTGATATAGTTAAGAAAAATCATATCCCGGCA
GTCTTTAGCGAGAGTACGATTTCCGATAAACCAGCGCGTCAGGTTGCGCGTGAAACCGGCGCACACTACGCGGTGTGCTC
TATGTCGATTCCTGAGCACAGAAAACGGCCCGGTACCGACGTATATCGACCTTCTTAA

Protein sequence : 
MHSIKKVTMLLGGLALTCSIAFQASATEKFKVITTFTIIADMAKNVAGDAAEVSSITKPGAEIHEYQPTPGDIKRAQGAQ
LILANGMNLELWFQRFYQHLNGVPEVIVSSGVTPVGITEGPYEGKPNPHAWMSPDNALIYVDNIRDALIKYDPANAQTYQ
RNADTYKAKITQTLAPLRKQITELPENQRWMVTSEGAFSYLARDLGLKELYLWPINADQQGTPQQVRKVVDIVKKNHIPA
VFSESTISDKPARQVARETGAHYAVCSMSIPEHRKRPGTDVYRPS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitA YP_217781.1 iron transporter: fur regulated Virulence SPI-1 Protein 3e-97 77
sitA NP_457255.1 Iron transport protein, periplasmic-binding protein Virulence SPI-1 Protein 7e-97 76
sitA NP_806464.1 iron transporter periplasmic-binding protein Virulence SPI-1 Protein 7e-97 76
sitA NP_461782.1 periplasmic binding protein Virulence SPI-1 Protein 7e-97 76
sitA AAD41065.1 SitA Virulence centisome 63 pathogenicity island Protein 5e-97 76

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sitA NP_753508.1 SitA protein BAC0349 Protein 3e-97 76
sitA NP_753508.1 SitA protein BAC0439 Protein 6e-79 65

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sitA NP_753508.1 SitA protein VFG0525 Protein 3e-97 76
sitA NP_753508.1 SitA protein VFG2157 Protein 8e-43 41