Gene Information

Name : sfaB (c1238)
Accession : NP_753152.1
Strain : Escherichia coli CFT073
Genome accession: NC_004431
Putative virulence/resistance : Virulence
Product : F1C and S fimbrial switch regulatory protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1187512 - 1187841 bp
Length : 330 bp
Strand : +
Note : Residues 1 to 102 of 109 are 82.35 pct identical to residues 1 to 102 of 104 from SwissProt.40 : >sp|P04744|PAPB_ECOLI MAJOR PILU SUBUNIT OPERON REGULATORY PROTEIN PAPB

DNA sequence : 
ATGGCACAGCATGAAGTTATTACCCGGGGAGGGGATGCTTTTTTACTAAAATTACGTGAGAGCGCGCTGTCATCCGGCTC
CATGTCTGAAGAACAATTTTTTTTACTGATAGGTATTTCCTCTATTCACAGTGACAGAGTTATTCTCGCTATGAAGGATT
ATCTGGTCAGTGGTCATTCCCGTAAAGATGTCTGCGAGAAATACCAGATGAATAATGGATATTTCAGTACAACGCTTGGG
CGCCTTACCAGGTTGAATGTCCTCGTTGCCAGACTTGCTCCTTATTATACTGATAGTGTATCAGCTATAGCTGAAGCTGC
TTCCCTGTAA

Protein sequence : 
MAQHEVITRGGDAFLLKLRESALSSGSMSEEQFFLLIGISSIHSDRVILAMKDYLVSGHSRKDVCEKYQMNNGYFSTTLG
RLTRLNVLVARLAPYYTDSVSAIAEAASL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sfaB CAC43422.1 SfaB protein Virulence PAI III 536 Protein 5e-46 100
papB AAC61719.1 PapB Virulence PAI I CFT073 Protein 7e-38 81
papB AAL67418.1 PapB Virulence PAI II CFT073 Protein 7e-38 81
papB AAZ04473.1 P pilus protein Virulence PAI I APEC-O1 Protein 7e-38 81
APECO1_3518 YP_854257.1 PapB-like protein Virulence PAI I APEC-O1 Protein 1e-37 81
papB YP_002414018.1 pap operon regulatory protein PapB Not tested Not named Protein 1e-37 81
prfB CAD42032.1 PrfB protein Virulence PAI II 536 Protein 7e-37 78

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sfaB NP_753152.1 F1C and S fimbrial switch regulatory protein VFG1641 Protein 2e-46 100
sfaB NP_753152.1 F1C and S fimbrial switch regulatory protein VFG1551 Protein 3e-37 78
sfaB NP_753152.1 F1C and S fimbrial switch regulatory protein VFG0436 Protein 7e-22 54
sfaB NP_753152.1 F1C and S fimbrial switch regulatory protein VFG0942 Protein 2e-15 43