Gene Information

Name : sfaC (c1237)
Accession : NP_753151.1
Strain : Escherichia coli CFT073
Genome accession: NC_004431
Putative virulence/resistance : Virulence
Product : F1C and S fimbrial switch regulatory protein
Function : -
COG functional category : K : Transcription
COG ID : COG2345
EC number : -
Position : 1186872 - 1187156 bp
Length : 285 bp
Strand : -
Note : Residues 22 to 94 of 94 are 93.15 pct identical to residues 5 to 77 of 77 from SwissProt.40 : >sp|P04743|PAPI_ECOLI Major pilus subunit operon regulatory protein

DNA sequence : 
TTGAATTGTCAAAAACAAGTCAGCCACTTATTATCCTTTTGCTTATATAGAGAGGATGATGATATGCAGAATGAAATAAT
GGGTTTTCTGAGCAGACATAATGGAGGGAAAACCGCAGAAATTGCGGAGGCGCTGGCGGTAACGGATTACCAGGCACGCT
ATTACCTGTTATTACTGGAAAAAGAAGGTATGGTTCAGCGCTCTCCGTTAAGACGAGGCATGGCAACATACTGGTTTCTG
AAAGGAGAGATGCAGGCGGGACAGAGCTGTTCTTCCACAACTTAA

Protein sequence : 
MNCQKQVSHLLSFCLYREDDDMQNEIMGFLSRHNGGKTAEIAEALAVTDYQARYYLLLLEKEGMVQRSPLRRGMATYWFL
KGEMQAGQSCSSTT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sfaC CAC16949.1 SfaC protein Virulence PAI III 536 Protein 9e-29 99
prfI CAD42033.1 PrfI protein Virulence PAI II 536 Protein 1e-27 94
papI_2 NP_757037.1 PapI protein Virulence PAI II CFT073 Protein 4e-27 92
papI AAL67419.1 PapI Virulence PAI II CFT073 Protein 3e-27 92
fooI AAT48694.1 fimbrial regulatory protein Virulence PAI I 4787 Protein 3e-27 92
papI YP_002414019.1 pap operon regulatory protein PapI Not tested Not named Protein 6e-27 91
papI NP_755468.1 PapI protein Virulence PAI I CFT073 Protein 6e-27 91

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sfaC NP_753151.1 F1C and S fimbrial switch regulatory protein VFG1640 Protein 4e-29 99
sfaC NP_753151.1 F1C and S fimbrial switch regulatory protein VFG1552 Protein 4e-28 94
sfaC NP_753151.1 F1C and S fimbrial switch regulatory protein VFG0891 Protein 1e-27 92
sfaC NP_753151.1 F1C and S fimbrial switch regulatory protein VFG0880 Protein 2e-27 91