Gene Information

Name : thyA (CE0919)
Accession : NP_737529.1
Strain : Corynebacterium efficiens YS-314
Genome accession: NC_004369
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 976555 - 977358 bp
Length : 804 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGACTGCCATTCCCACCCCATATGAGGACCTCCTCCGCACCATCAGAGACGAAGGCGCCCATAAGGACGATCGCACCGG
CACCGGCACCACCTCCCTGTTCGGCCAGCAGATCCGTTACAACCTGCAGGAGGGTTTCCCCCTCCTGACCACCAAGAAGG
TTCATTTCCACTCCGTGGTCGGTGAACTGCTGTGGTTCCTGCGCGGTGACTCCAACGTCCGTTGGCTCCAGGACAACAAC
ATCCGCATCTGGAACGAGTGGGCCGATGAGGACGGCGAGCTCGGTCCCGTCTACGGCGTGCAGTGGCGCAGCTGGCCCAC
CCCGGACGGTCGCCACATCGACCAGATCTCGCGTGCACTGGAGATGCTGAAGAACAATCCGGATTCCCGCCGTAACATCG
TCTCCGCATGGAACGTCTCCGAACTGGAGAACATGGCGCTTCCCCCCTGTCATCTGCTGTTCCAGCTGTATGTCGCCGAT
GGGAAACTGTCCTGCCAGCTCTACCAGCGCAGCGCCGACATGTTCCTCGGTGTGCCCTTCAACATCGCCTCCTACGCCCT
GCTGACGCACATGTTCGCCCAGCAGGCAGACCTGGAGGTGGGTGAGTTCATCTGGACCGGCGGTGACTGCCACATCTATG
ACAATCACACCGAACAGGTCGATGAACAGCTGAGCCGCGCGGCGCGCCCCTACCCCACCCTGGAACTGAACAAGGCTGCG
TCCCTGTTCGACTACACCTTCGAGGACATTGCCGTGAGCAACTACGATCCGCACCCGCTCATCCGCGGCAAGGTCGCGGT
ATGA

Protein sequence :
MTAIPTPYEDLLRTIRDEGAHKDDRTGTGTTSLFGQQIRYNLQEGFPLLTTKKVHFHSVVGELLWFLRGDSNVRWLQDNN
IRIWNEWADEDGELGPVYGVQWRSWPTPDGRHIDQISRALEMLKNNPDSRRNIVSAWNVSELENMALPPCHLLFQLYVAD
GKLSCQLYQRSADMFLGVPFNIASYALLTHMFAQQADLEVGEFIWTGGDCHIYDNHTEQVDEQLSRAARPYPTLELNKAA
SLFDYTFEDIAVSNYDPHPLIRGKVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 5e-109 84