Gene Information

Name : guaA (CE0615)
Accession : NP_737225.1
Strain : Corynebacterium efficiens YS-314
Genome accession: NC_004369
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 651644 - 653215 bp
Length : 1572 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGAGCCTTACACCTAATCATCGCCCAGTACTCGTTGTCGACTACGGTGCACAGTACGCGCAGCTGATCGCACGACGAGT
GCGTGAGGCCGGCATCTACTCCGAAGTCATCCCGCACACCGCCACCCCGCAGGAGATTCAGGAAAAGAACCCTGTTGCGC
TGGTGTTGTCCGGTGGACCGTCGTCTGTGTATGCAGAGGACGCGCCGGGTATCGATCCGGACATCCTGAAGTTGGGGCTG
CCGGTCTTCGGCATCTGCTACGGCTTCCAGGCCATGACCCACGCGCTGGGTGGCAAGGTTGCCGCCACCGGCAAGCGTGA
GTACGGCCGTACTGATCTTGAGGTCAAGGGTGGTGTTCTGCACGACGGTCTGGAGCTGTCCCACAAGGTGTGGATGAGCC
ATGGCGATGCTGTGTCCGAGGCCCCTGAGGGTTTCACCGTCACCGCTTCCTCCGAGGCGGCACCGGTCGCGGCTTTCGAG
AATGTCGAGGCCAAGATGGCTGGTGTCCAGTACCACCCCGAGGTGCTGCACTCCCCGCATGGTCAGCAGGTTCTCACCCG
CTTCCTCACCGAGATCGCCGGCCTGGAGCAGAACTGGACTGCGGCCAACATTGCGGAGGAACTCGTCGAGAAGATCCGTG
AGCAGGTCGGCCCTGAGGGTCGTGCCATCTGTGGTCTGTCCGGTGGCGTGGATTCCGCCGTTGCCGCAGCCCTGGTGCAG
CGCGCCATCGGTGACCGCCTGACCTGTGTCTTTGTTGACCACGGTCTGCTGCGCGCCGGTGAGCGTGAGCAGGTGGAGAA
GGATTTCGTGGCTGCCACCGGCGCGAAGCTGGTCACCGTCGATGAGCGTAAGGCGTTCCTGGATAAGCTGGCCGGTGTCA
CCGAGCCGGAGGCCAAGCGCAAGGCCATCGGTGCGGAGTTCATCCGTTCCTTCGAGCGCGCTGTCGCCGGTGTGCTGGAG
GATTCCCCGGAGGGTTCCACCGTGGACTTCCTGGTCCAGGGCACCCTCTACCCGGATGTGGTGGAGTCCGGCGGCGGTGC
CGGTACCGCCAACATCAAGAGCCACCACAACGTGGGCGGGCTGCCTGATGATGTCGAGTTCGAGCTCGTCGAGCCCCTGC
GCCTGCTGTTCAAGGACGAGGTCCGTGCGGTTGGCCGCGAGCTCGGCCTGCCCGAGGTCATCGTTGCCCGTCAGCCGTTC
CCGGGACCGGGCCTGGGTATCCGCATCATCGGTGAGGTCACCGAGGAGCGTCTGGAGACCCTCCGCCACGCCGATCTGAT
CGCCCGCACCGAGCTCACCGCAGCCGGCCTGGATGGCATCATCTGGCAGTGCCCGGTGGTCCTGCTCGCCGATGTCCGTT
CTGTCGGTGTCCAGGGTGACGGCCGCACTTACGGTCACCCGATCGTGCTGCGCCCGGTGTCCTCCGAGGATGCCATGACC
GCCGACTGGACCCGCCTGCCGTATGAGGTCCTGGAGCGTATCTCCACCCGCATCACCAATGAGGTCGCCGACGTCAACCG
CGTTGTGCTCGACGTGACCTCGAAGCCACCGGGAACCATCGAGTGGGAGTAG

Protein sequence :
MSLTPNHRPVLVVDYGAQYAQLIARRVREAGIYSEVIPHTATPQEIQEKNPVALVLSGGPSSVYAEDAPGIDPDILKLGL
PVFGICYGFQAMTHALGGKVAATGKREYGRTDLEVKGGVLHDGLELSHKVWMSHGDAVSEAPEGFTVTASSEAAPVAAFE
NVEAKMAGVQYHPEVLHSPHGQQVLTRFLTEIAGLEQNWTAANIAEELVEKIREQVGPEGRAICGLSGGVDSAVAAALVQ
RAIGDRLTCVFVDHGLLRAGEREQVEKDFVAATGAKLVTVDERKAFLDKLAGVTEPEAKRKAIGAEFIRSFERAVAGVLE
DSPEGSTVDFLVQGTLYPDVVESGGGAGTANIKSHHNVGGLPDDVEFELVEPLRLLFKDEVRAVGRELGLPEVIVARQPF
PGPGLGIRIIGEVTEERLETLRHADLIARTELTAAGLDGIIWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSSEDAMT
ADWTRLPYEVLERISTRITNEVADVNRVVLDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 0.0 87
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-132 51
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 4e-132 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-132 51