Gene Information

Name : leuS (CE2848)
Accession : NP_739458.1
Strain : Corynebacterium efficiens YS-314
Genome accession: NC_004369
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 3027539 - 3030412 bp
Length : 2874 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGACGAATCCGAGCGAGGGCACCTCTTCTTCCGCACAGTCACTGGCCTACCGGTACACCCCGGAGCTGGCGAATGCGAT
TGAGCGTGAGTGGCAGAATTACTGGACCGACAAGGGCACCTTCAACGCGCCGAACCCGGTGGGTGATCTGGCGCCGGAGG
ACGGTCGTGAGCTTCCCGGGGACAAGCTGTTTGTCCAGGATATGTTCCCCTACCCCTCCGGTGCCGGCCTGCATGTGGGC
CACCCGCTGGGGTACATCGCCACGGATGTCTTCGCCCGCTACAACCGCATGCTGGGCAAGAACGTCCTGCACACCCTGGG
CTATGACGCCTTCGGCCTGCCGGCGGAGCAGTACGCCATCCAGACCGGTACCCACCCGCGTACCACCACCATGGCCAATA
TCGAGAACATGAAGCGTCAGCTCGGTGCGCTCGGCCTGGGTCATGACCCGCGTCGCGCCGTCGCCTCCACCGACCCGGAG
TTCTACAAGTGGACCCAGTGGATCTTCCTGCAGATCTTCAACTCCTGGTTCGATGAGGAGCAGCAGAAGGCACGCCCGAT
CTCGGAGCTGATCCCCCTGCTGGAATCCGGCGAGATCCCCACCAGGGACGGTGCTGATTACAACGGGCTGGATCGCGTCG
CAAAGCAGAAGGCCATCGACGAGTTCCGCCTGGTCTACCGCTCCAACTCCACGGTGAACTGGTGCCCGGGTCTGGGCACC
GTGCTGGCCAATGAGGAGGTCACCGCCGATGGCCGCTCGGAGCGCGGCAACTTCCCGGTGTTCCGCAAGAACCTCTCCCA
GTGGATGATGCGCATCACCGCCTACTCCGACCGCCTCATCGATGATCTGGAGCTGCTCGACTGGCCGGAGAAGGTCAAAT
CCATGCAGCGCAACTGGATCGGCCGTTCCCGCGGTGCGGAGGTCGATTTCACCGCTGAGGGTGAGACCATCACCGTATTC
ACCACCCGCCCCGACACCCTCTTCGGTGCCACCTACATGGTGCTGGCACCCGAGCATGAGCTTGTCGACGTCCTCGTGTC
CCGCGGCACCGGTTCCTATGACGGCGTCGACCCGCGCTGGACCAACGGCCAGGCCACCCCTGCTGAGGCCGTGGCCGCCT
ACCGCGCCTCCATCGCTGCAAAGTCCGACCTGGAACGCCAGGAGAACAAGGACAAGACCGGTGTGTTCCTCGGTGTGCAC
GCCACCAACCCGGTCAACGGTGAGCAGATCCCCGTCTTCATCGCCGACTACGTACTCACCGGGTACGGCACCGGCGCCAT
CATGGCCGTCCCCGCCCACGATGACCGTGACTACGAGTTCGCCACCGTCTTCGGCCTGCCGATCGTCGAGGTCGTCGCTG
GCGGCAACATCGCCGAGGCCGCCTACACCGCCTCCGGTGAGTCCATCAACTCCGCCAATGACCAGGGCTTAGACATCAAC
GGCCTGGCCATGGTCGATGCGGTGGCACGCACCATCGAATGGCTGGAGGAGAAGCAGCTCGGTCGTGGCACCATCCAGTA
CAAGCTGCGTGACTGGCTGTTCGCCCGCCAGCGCTACTGGGGCGAGCCCTTCCCGGTGGTCTACGACGAGGACGGTGTGG
CCTACGCCCTGCCCGAGTCGATGCTGCCCGTTGAGCTGCCCGAGGTCGAGGACTACAAGCCGGTCTCCTTCGACCCGGAG
GACGCCGATTCCGAGCCCTCCCCGCCCCTGGCCAAGGCCCGCGAGTGGGTGGAGGTGGAACTCGACCTCGGTGACGGTGT
AAAGAAGTACACCCGCGACACCAACGTCATGCCGCAGTGGGCCGGGTCCTCCTGGTACCAGCTGCGTTATATCGACCCCA
CCAATGATGACCAGTTCTGCAACCTGGAGAACGAGGCCTACTGGACCGGCCCCCGCCCGGATGTCCATGGCCCCAACGAT
CCCGGTGGCGTGGACCTCTATGTCGGTGGCGTCGAGCACGCCGTCCTGCACCTGCTGTACTCCCGTTTCTGGCACAAGGT
CCTCTACGACCTGGGGTATGTCACCTCGAAGGAGCCCTACCGCCGCCTGTACAACCAGGGATACATCCAGGCCTTCGCCT
ACACCGACTCCCGTGGCGTGTACGTCCCGGCCGAGGAGGTCGAGGAGAAGGACGGCAAGTTCTTCTACCAGGGTGAGGAG
GTCACCCAGGAGTACGGCAAGATGGGCAAGTCCCTGAAGAACGCCGTCGCACCGGATGACATCTGCAACAACTACGGCGC
GGACACCCTGCGCGTGTACGAGATGTCCATGGGCCCACTCGACACCTCCCGCCCCTGGGCGACCAAGGACGTGGTGGGTG
CGCAGCGCTTCCTGCAGCGTCTGTGGCGCCTGATCGTGGATGAGAACACCGGCGAGGTGCTCACCCGCGACGAGGCACTG
ACCGATGAGGACAACAAGCATCTGCACCGCACCATCGCCGGTGTGCGCGATGATTACGCCAACCTGCGCGTGAACACCGT
GGTGGCCAAGCTCATCGAGTACGTCAACTACCTCACCAAGACCTACCCCGACACCATCCCGACCGGTGCCGTCCTGCCGC
TGGTGGTCATGGTCTCCCCCGTCGCCCCGCACATCGCGGAGGAGCTGTGGAAGAAACTCGGCCACACCGACACCGTCACC
TACGAGCCCTTCCCCACCTTCGAGGAGAAGTGGCTCACCGACGATGAGGTCGAACTGCCGGTCCAGATCAACGGCAAGGT
GCGCAGCCGCATCACCGTCGCCGCCGACGCCTCCCAGGAGCAGATCATCGAGGTCGCGCTTGCCGACGAGAAGATCGCCC
TCCAGATCGAAGGCAAGAACCTGATCAAGCAGATCGTCATCCCGGGCCGCATGGTCAACCTCGTGGTGAAATAA

Protein sequence :
MTNPSEGTSSSAQSLAYRYTPELANAIEREWQNYWTDKGTFNAPNPVGDLAPEDGRELPGDKLFVQDMFPYPSGAGLHVG
HPLGYIATDVFARYNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMANIENMKRQLGALGLGHDPRRAVASTDPE
FYKWTQWIFLQIFNSWFDEEQQKARPISELIPLLESGEIPTRDGADYNGLDRVAKQKAIDEFRLVYRSNSTVNWCPGLGT
VLANEEVTADGRSERGNFPVFRKNLSQWMMRITAYSDRLIDDLELLDWPEKVKSMQRNWIGRSRGAEVDFTAEGETITVF
TTRPDTLFGATYMVLAPEHELVDVLVSRGTGSYDGVDPRWTNGQATPAEAVAAYRASIAAKSDLERQENKDKTGVFLGVH
ATNPVNGEQIPVFIADYVLTGYGTGAIMAVPAHDDRDYEFATVFGLPIVEVVAGGNIAEAAYTASGESINSANDQGLDIN
GLAMVDAVARTIEWLEEKQLGRGTIQYKLRDWLFARQRYWGEPFPVVYDEDGVAYALPESMLPVELPEVEDYKPVSFDPE
DADSEPSPPLAKAREWVEVELDLGDGVKKYTRDTNVMPQWAGSSWYQLRYIDPTNDDQFCNLENEAYWTGPRPDVHGPND
PGGVDLYVGGVEHAVLHLLYSRFWHKVLYDLGYVTSKEPYRRLYNQGYIQAFAYTDSRGVYVPAEEVEEKDGKFFYQGEE
VTQEYGKMGKSLKNAVAPDDICNNYGADTLRVYEMSMGPLDTSRPWATKDVVGAQRFLQRLWRLIVDENTGEVLTRDEAL
TDEDNKHLHRTIAGVRDDYANLRVNTVVAKLIEYVNYLTKTYPDTIPTGAVLPLVVMVSPVAPHIAEELWKKLGHTDTVT
YEPFPTFEEKWLTDDEVELPVQINGKVRSRITVAADASQEQIIEVALADEKIALQIEGKNLIKQIVIPGRMVNLVVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 8e-158 49