Gene Information

Name : metB (CE2343)
Accession : NP_738953.1
Strain : Corynebacterium efficiens YS-314
Genome accession: NC_004369
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 2494872 - 2496101 bp
Length : 1230 bp
Strand : -
Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine

DNA sequence :
ATGGACAGCTTGGTCTATTATTGCCCACAGCCCCGCAGTATATTTCTTCAGGAGTTGATCCAGTTGTCCCACAAGCCCAC
CGACCAGGGTTTTTCCACCGCCTCGATCCACGCCGGATACGAGCCGGACGAATACTATGGTTCGATCAACGTCCCGATCT
ACGCCTCCACCACCTTCGCGCAGAACGGCCCCAATGAGCTGCGCCGTGGTTATGAATACACCCGTGTGGGTAACCCCACC
ATCACCGTGCTGGAGCAAACCGTCGCCGCACTCGAGGGCGCCGAGTACGGTCGTGCCTTCTCCTCCGGCATGGCGGCCAC
CGACATCCTGTTCCGCATTCTGCTCAAGCCGGGCGACCACATCATCCTGGGCAATGACGCCTACGGTGGCACCTTCCGGC
TCATCGACACCGTCTTCGTCGCCTGGGGTGTGGAATACACCGTGGTGGACACCTCCAACGTTGATGAGGTCAAGGCCGCC
ATCCGCGACAACACCAAGCTGATCTGGGTGGAGACCCCCACCAACCCGGCACTGGCCATCACCGACATCGAGGCCGTGGC
CAAGGCCGCCGAGGGCACCGACGCCAAGCTCGTGGTGGATAACACCTTCGCCTCCCCCTACCTGCAGCAGCCGCTGAAGC
TCGGCGCCTACGCCGTGCTGCACTCCACCACCAAGTACATCGGTGGTCACTCCGATGTGGTCGGTGGACTCGTGGTGACC
AATGACCAGCAGCTGGATGAGGAACTGCTGTTCATGCAGGGTAGCATCGGCCCGATCCCCAGCGTGTTCGACGCCTACCT
CACCGGCCGCGGCGTCAAGACCCTCGCTGTGCGCATGGACCGCCACTGCGACAACGCCGAGAAGATCGCCGAATTCCTTG
ACTCCCGCCCCGAGGTGTCCACCGTGCTCTACCCGGGCCTGGAATCCCACCCGGGACACGAGGTGGCCAAGCGCCAGATG
AAGCGCTTCGGCGGCATGATCTCCGTGCGCTTCGCCGGCGGAGAGGAGGCCGCCAAGAAGTTTTGTACCTCCACCAAGCT
GATCTGCCTGGCGGAATCCCTCGGCGGTGTGGAATCCCTGCTGGAGCACCCCGCCACCATGACCCACCAGTCCGCAGCCG
GTTCCCAGCTGGAGGTGCCCCGTGACCTGGTGCGCATCTCCATCGGCATCGAGGACATCGAGGACCTGCTTGCCGACGTT
GAACAGGCCCTGGACCAGCTGCCCCAGTAG

Protein sequence :
MDSLVYYCPQPRSIFLQELIQLSHKPTDQGFSTASIHAGYEPDEYYGSINVPIYASTTFAQNGPNELRRGYEYTRVGNPT
ITVLEQTVAALEGAEYGRAFSSGMAATDILFRILLKPGDHIILGNDAYGGTFRLIDTVFVAWGVEYTVVDTSNVDEVKAA
IRDNTKLIWVETPTNPALAITDIEAVAKAAEGTDAKLVVDNTFASPYLQQPLKLGAYAVLHSTTKYIGGHSDVVGGLVVT
NDQQLDEELLFMQGSIGPIPSVFDAYLTGRGVKTLAVRMDRHCDNAEKIAEFLDSRPEVSTVLYPGLESHPGHEVAKRQM
KRFGGMISVRFAGGEEAAKKFCTSTKLICLAESLGGVESLLEHPATMTHQSAAGSQLEVPRDLVRISIGIEDIEDLLADV
EQALDQLPQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-71 47
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-72 47
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 7e-59 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB NP_738953.1 cystathionine gamma-synthase BAC0207 Protein 9e-68 43