Gene Information

Name : tpx (CE1141)
Accession : NP_737751.1
Strain : Corynebacterium efficiens YS-314
Genome accession: NC_004369
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : -
Position : 1198667 - 1199164 bp
Length : 498 bp
Strand : +
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein

DNA sequence : 
ATGGCTACGACTCATTTTGATGGTACTGACACCCCCACCTCCGGCGAACTCCCGGCGGTGGGCGACACCCTTCCCGACTT
CACCGTCGTCGACACCAACCTCGGCGAGGTGTCCCTGTCTGATCTCAAGGGCAAGAAACTCGTTCTCAACATCTTCCCCT
CGGTGGACACCGGACTGTGCGCGGAGTCCGTGCGCAGGTTCAACGCCGAGGCAGCAGGTCTGGACAACACCACCGTGCTG
TGTGTATCCAAGGACCTGCCCTTCGCCCTCGGACGCTTCTGCGGTGCCGAGGGCCTGGACAATGTCACCGCCGCCTCCGC
ATTCCGCTCCACCTTCGGTGAGGATTATGGCGTGGTGCTGGAAGGCTCCCCCCTCAAGGGTCTGCTGGCCCGCAGCGTCA
TCGTTGCAGATGAGGACGGCAAGGTCATCTACACCCAGCTGGTTGATGAGATCAAGACCGAACCGGACTACGCCTCCGCC
ATCAAGGCGCTGGGTTAA

Protein sequence : 
MATTHFDGTDTPTSGELPAVGDTLPDFTVVDTNLGEVSLSDLKGKKLVLNIFPSVDTGLCAESVRRFNAEAAGLDNTTVL
CVSKDLPFALGRFCGAEGLDNVTAASAFRSTFGEDYGVVLEGSPLKGLLARSVIVADEDGKVIYTQLVDEIKTEPDYASA
IKALG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 3e-34 47
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 4e-34 47
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 6e-34 46
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 9e-34 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx NP_737751.1 thiol peroxidase VFG0087 Protein 1e-34 47