Gene Information

Name : gbs0268 (gbs0268)
Accession : NP_734737.1
Strain : Streptococcus agalactiae NEM316
Genome accession: NC_004368
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 287111 - 289096 bp
Length : 1986 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGACATTTGACACCATTGATCAATTAGCGGTTAATACAGTCCGCACGCTTTCTATTGATGCTATCCAAGCAGCAAATTC
TGGGCACCCAGGTCTTCCTATGGGAGCTGCGCCTATGGCTTATGTGCTTTGGAATAAATTCTTAAATGTAAACCCAAAAA
CAAGTCGCAATTGGACAAACCGTGACCGTTTTGTGCTATCAGCTGGGCATGGTTCAGCTCTTCTTTATAGCCTACTTCAT
TTAGCTGGCTATGATTTATCAATTGATGATTTAAAACAATTCCGCCAATGGGGATCAAAAACACCTGGACATCCAGAAGT
TAACCATACTGATGGTGTAGAAGCAACAACTGGACCTTTAGGGCAAGGTATTGCTAATGCTGTTGGTATGGCAATGGCTG
AAGCTCATTTGGCTGCTAAATTTAATAAACCAGGCTTTGATTTAGTTGATCATTACACTTATACACTTCATGGTGATGGT
TGTTTGATGGAGGGTGTTAGCCAAGAAGCTGCCAGTCTTGCTGGACACTTAAAACTTGGTAAATTGGTCCTTCTTTATGA
TTCAAATGATATCTCACTTGATGGTCCAACGTCTCAATCATTTACAGAAGATGTTAAAGGGCGTTTTGAATCATATGGTT
GGCAACATATCTTAGTTAAAGATGGTAATGATTTAGAAGCGATTGCTGCAGCAATTGAAGCTGCTAAAGCTGAAACTGAT
AAACCAACCATTATTGAAGTTAAAACTATTATTGGATTTGGCGCAGAGAAACAGGGAACATCTTCAGTTCATGGAGCGCC
ACTTGGTGCAGAAGGTATTACTTTTGCCAAGAAGGCTTATGGATGGGAATATCCAGACTTTACTGTTCCTGCTGAAGTTG
TAGCTCGATTTGCCTCAGATCTTCAAGCGCGTGGTGCGAAGGCAGAAGAGGCATGGAATGATCTTTTTGCTAAATATGAA
GTTGAGTATCCAGAATTAGCAGCTGAATACAAAGAAGCTTTTGCTGGCCAAGCTGAGACAGTTGAATTGAAAGCTCATGA
CCTAGGTTCATCAGTGGCTAGTCGTGTTTCAAGCCAACAAGCTATTCAACAATTATCGACTCAATTACCGAACCTCTGGG
GAGGGTCAGCAGACCTCTCAGCTTCTAATAACACAATGGTAGCAGCAGAAACAGATTTCCAAGCAAGTAATTACGCTGGG
CGTAACATTTGGTTTGGTGTACGTGAATTTGCAATGGCTGCTGCAATGAATGGAATTGCGCTTCACGGTGGGACTCGTGT
TTATGGGGGTACATTCTTTGTCTTCTCAAACTACTTGTTACCAGCAGTACGTATGGCTGCACTTCAAAACTTGCCAACTG
TCTATGTTATGACACATGATTCTATTGCTGTTGGAGAAGATGGGCCAACTCATGAGCCAATAGAACAATTAGCATCAGTG
CGCTCAATGCCTAATTTGAACGTTATCCGTCCCGCAGACGGTAATGAAACAAACGCTGCATGGCAACGAGCTGTATCAGA
GACAGATCGACCAACGATGCTTGTTTTAACACGTCAAAACTTACCAGTTCTTGAAGGAACATCAGAATTAGCCCAAGAAG
GGGTTAATAAAGGTGCTTATATTTTATCAGAAGCTAAAGGTGAACTTGATGGTATCATCATTGCAACAGGTTCAGAAGTT
AAATTAGCTTTAGATACTCAAGACAAACTTGAGTCAGAGGGCATCCATGTTCGCGTCGTATCTATGCCAGCACAAAACAT
TTTTGATGAACAAGAGGCTTCATATCAAGAGCAAGTGCTTCCATCAGCTGTTACAAAACGTCTTGCTATTGAGGCAGGAT
CAAGCTTCGGTTGGGGTAAATATGTTGGTTTAAATGGGCTAACACTTACTATTGATACTTGGGGAGCATCAGCACCAGGT
AACAGAATTTTCGAAGAGTATGGCTTTACAGTTGAGAATGCTGTATCGCTATATAAAGAACTTTAA

Protein sequence :
MTFDTIDQLAVNTVRTLSIDAIQAANSGHPGLPMGAAPMAYVLWNKFLNVNPKTSRNWTNRDRFVLSAGHGSALLYSLLH
LAGYDLSIDDLKQFRQWGSKTPGHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKPGFDLVDHYTYTLHGDG
CLMEGVSQEAASLAGHLKLGKLVLLYDSNDISLDGPTSQSFTEDVKGRFESYGWQHILVKDGNDLEAIAAAIEAAKAETD
KPTIIEVKTIIGFGAEKQGTSSVHGAPLGAEGITFAKKAYGWEYPDFTVPAEVVARFASDLQARGAKAEEAWNDLFAKYE
VEYPELAAEYKEAFAGQAETVELKAHDLGSSVASRVSSQQAIQQLSTQLPNLWGGSADLSASNNTMVAAETDFQASNYAG
RNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQNLPTVYVMTHDSIAVGEDGPTHEPIEQLASV
RSMPNLNVIRPADGNETNAAWQRAVSETDRPTMLVLTRQNLPVLEGTSELAQEGVNKGAYILSEAKGELDGIIIATGSEV
KLALDTQDKLESEGIHVRVVSMPAQNIFDEQEASYQEQVLPSAVTKRLAIEAGSSFGWGKYVGLNGLTLTIDTWGASAPG
NRIFEEYGFTVENAVSLYKEL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 4e-142 52
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 3e-140 50