Gene Information

Name : clp (SMU_956)
Accession : NP_721354.1
Strain : Streptococcus mutans UA159
Genome accession: NC_004350
Putative virulence/resistance : Virulence
Product : Clp-like ATP-dependent protease, ATP-binding subunit
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 905494 - 907599 bp
Length : 2106 bp
Strand : -
Note : Best Blastp Hit: gb|AAA68910.1| (L34677) Clp-like ATP-dependent protease binding subunit [Bos taurus]

DNA sequence :
ATGGCAAATTTTAATGGACGCGATCCTTTTGGAAATATGGACGATATTTTTAATCAATTAATGGGTAATATGGGGGGATA
CAACTCTGAAAACCGTCGATATTTAATTAACGGTCGTGAAGTAAGTCCCGAAGAATTCGCACAATACAGACAAACAGGTA
AGCTTCCTGGCAATCCAGAAATACAGCAAGCTCAAGCTGCTGCTAGAACTCCAAAAGAAGACAGTATTTTGACTAAGCTT
GGTAACAATTTAACCGAAGAAGCCAGACAAGGTAACCTTGATCCTGTTATTGGACGGAATAAAGAAATTCAAGAAACTGC
TGAGATCTTAGCTCGGCGGACTAAAAACAATCCTGTTCTGGTCGGTGATGCCGGTGTTGGTAAAACAGCTGTCGTTGAAG
GCTTAGCACAGGCTATTGTTAACGGTGATGTCCCTGCCAGTATTAAAAATAAGGAAGTTATTTCTATTGATATTTCAGGA
TTAGAAGCTGGTACACAATACCGTGGTGCTTTCGAAGAAAATATTCAAAACTTGGTTAAAGAAGTCAAAGAAGCTGGCAA
TATCATCCTCTTCTTTGATGAAATTCATCAAATTTTAGGTGCTGGTTCAACTGGTGGTGACAGTGGTTCTAAAGGTTTGG
CAGACATTATCAAACCTGCTTTATCTCGCGGTGAATTGACTGTTATCGGTGCTACTACGCAAGATGAATACCGCAATACC
ATTATGAAAAACGCTGCATTGGCACGTCGTTTCAACGAAGTCAAAGTAAATGCACCTTCTGCTGAGGATACTTACGAAAT
TTTAAAAGGTATTTCAGCTCTCTACGAACAACATCATAATGTTATTTTGCCTAAGGAAGTTTTAAAAGCTGCTGTTGACT
TATCCGTACAATACATCCCGCAACGCAGTCTGCCTGATAAGGCCATTGACCTTGTTGATATGACAGCTGCTCATCTGGCT
GCTCAACATCCAGCAACTGATGTTAAGACACTTGAAAAAGAAATTCAAACTGAAAAAGATAAACAACAAGCTGCTGCTGA
AAAAGAAGATTATGAGGAAGCTCTTAAATCAAAAACTAAAATTGATAAACTGCAAGCACAAATTGACAATCATACTGAAG
GGCAAAAGGTCACTGCTACTATCAACGATGTGGCTGAGGCAGTTGAACGTTTGACAGGTATCCCTGTTTCGCAAATGGGA
AGCAGTGACATTGAACGTCTAAAAGAAATGAATTCTCGTCTCAAAGGCAAAGTTATTGGTCAAGATGAAGCTGTTGAAGC
TGTTTCACGCGCTATTCGCCGTAACCGTGCTGGTTTTGATGAAGGCAACCGTCCAATCGGCAGTTTCCTTTTTGTCGGAC
CTACTGGTGTTGGTAAAACAGAATTGGCTAAGCAGTTAGCCTTGGATATGTTTGGTTCTAAAGACTCTATTATCCGTCTT
GATATGTCAGAGTACAGTGATCGTACAGCTGTTTCCAAATTGATTGGTACTACTGCCGGTTATGTCGGCTATGATGATAA
CAGCAATACATTGACTGAACGTGTTCGCCGCAATCCTTATTCTATCGTTTTACTTGATGAGATTGAAAAGGCTGACTCTC
AAGTCATCACTCTTCTCCTTCAAGTATTGGATGATGGTCGTTTGACAGACGGACAAGGTAATACCATTAACTTTAAGAAT
ACCGTGATTATTGCAACTTCTAATGCTGGTTTTGGTAATGAAGCATTAACTGGTCAGGAAGATAAGGACATGAAGATCAT
GGATCGCATTGCCCCTTACTTCCGTCCCGAGTTTTTAAACCGTTTCAATGCAGTTATTGAATTCTCTCACTTAAGCAAAG
AAGACTTGGATGAAATCGTTAATCTCATGCTATCTGAAGTGAATACCACGCTTGCTAAGAAAGGAATTGATCTTGTTGTC
AGTGACAGCGCCAAGGCACATTTGATTGAAGAAGGTTATGACGAAGCAATGGGTGTTCGTCCATTACGCCGAGTTATCGA
GCAAGAAATTCGTGATAAAGTAACTGACTTCTATCTTGATCATACAGATGTTAAACATCTCAAAGCTGAAATGCAAGATG
ACAAATTGATTATTGAAGAAGCTTAA

Protein sequence :
MANFNGRDPFGNMDDIFNQLMGNMGGYNSENRRYLINGREVSPEEFAQYRQTGKLPGNPEIQQAQAAARTPKEDSILTKL
GNNLTEEARQGNLDPVIGRNKEIQETAEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPASIKNKEVISIDISG
LEAGTQYRGAFEENIQNLVKEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADIIKPALSRGELTVIGATTQDEYRNT
IMKNAALARRFNEVKVNAPSAEDTYEILKGISALYEQHHNVILPKEVLKAAVDLSVQYIPQRSLPDKAIDLVDMTAAHLA
AQHPATDVKTLEKEIQTEKDKQQAAAEKEDYEEALKSKTKIDKLQAQIDNHTEGQKVTATINDVAEAVERLTGIPVSQMG
SSDIERLKEMNSRLKGKVIGQDEAVEAVSRAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGSKDSIIRL
DMSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIVLLDEIEKADSQVITLLLQVLDDGRLTDGQGNTINFKN
TVIIATSNAGFGNEALTGQEDKDMKIMDRIAPYFRPEFLNRFNAVIEFSHLSKEDLDEIVNLMLSEVNTTLAKKGIDLVV
SDSAKAHLIEEGYDEAMGVRPLRRVIEQEIRDKVTDFYLDHTDVKHLKAEMQDDKLIIEEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 6e-135 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clp NP_721354.1 Clp-like ATP-dependent protease, ATP-binding subunit VFG0080 Protein 1e-152 48
clp NP_721354.1 Clp-like ATP-dependent protease, ATP-binding subunit VFG0079 Protein 3e-141 45