Gene Information

Name : tkt (SMU_291)
Accession : NP_720749.1
Strain : Streptococcus mutans UA159
Genome accession: NC_004350
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : -
Position : 277894 - 279870 bp
Length : 1977 bp
Strand : +
Note : Best Blastp Hit: sp|P22976|TKT_STRPN PROBABLE TRANSKETOLASE (TK) >gi|279499|pir||XJSOKP transketolase (EC 2.2.1.1) homolog - Streptococcus pneumoniae >gi|153792|gb|AAA26967.1| (M31296) recP peptide [Streptococcus pneumoniae]

DNA sequence :
ATGTCAGATTTATCGGTTAATGCCATTCGCTTTTTAGGGGTAGATGCTATTGAAAAGTCTAAGTCGGGTCACCCGGGTGT
TGTCATGGGCGCTGCCCCAATGGCTTACAGTCTATATACTAAGCATTTACGTGTTAACCCAAGTCAGCCAAATTGGATTA
ACCGTGACCGTTTTGTTTTGTCAGCTGGTCATGGCTCAATGCTTTTATATGCTCTCTTGCACTTGTCGGGATTTGAAGAT
ATTTCTATTGATGAAATCAAAAATTTCCGTCAGTGGGGCTCTAAAACACCGGGGCACCCTGAGTATGGCCATACCGTAGG
TGTTGATGTGACAACAGGCCCTCTTGGCCAAGGGATTTCAATGGCTGTTGGTTTGGCTCAAGCTGAACGTTTCTTAGCTG
CTAAATACAATCGTGAAGGCTACCCTATTTTTGATCACTATACTTATGTTATTGCCGGTGATGGTGATTTTATGGAAGGT
GTTTCTGGCGAAGCGTCATCCTATGCTGCCAAACAAAATTTGGATAAACTGATTGTTCTTTATGATTCTAATGATATTTG
TTTGGATGGTGAAACCAATGATGCGTTCACTGAAAGTGTTCGTGCACGATATGATGCTTATGGATGGCATACAATCTTAG
TTGAAGATGGCAATAATATTGAAGCTATTGGACTTGCTATTGAAGAAGCAAAGGCAGCTGGCAAACCTTCTCTTATTGAA
ATTAAAACTGTGATTGGCTACGGTGCTCCAACTAAAGGCGGTACCAATGCTGTTCATGGTGCACCACTTGGAGCTGAAGA
AGCAGCTGCTACTCGTAAGGCTCTCAATTGGGGTTATGCTCCTTTTGAAGTTCCTCAAGAGGTTTATGATGATTTCAAAG
AAAATGTTGCGGATCGTGGTGAAGCTGCTTACGATGCTTGGTCAAATCTTGTTGGAGAATATCGACAAGCTTATCCTAAA
GAGGCGCGTGAAGTGGATGCAATTATTGATGGAAAAGATCCTGTGGAAATCAAAGAAGCTGATTTTCCAGTCTACGAAAA
TGGTTTCTCTCAAGCAACGCGTAATTCTAGTCAAGATGCCATCAATGCTGCGGCAGACGTACTACCTAACTTTCTTGGAG
GATCTGCTGATCTTGCGCATTCTAACATGACTTACATTAAAGCAGATGGGCTTCAAGATGCTGATCATCCGCTTAACCGT
AACATCCAGTTTGGTGTTCGTGAATTTGCTATGGGTACTGTCTTAAATGGTATGGCTCTTCATGGCGGACTGCGTGTTTA
TGGCGGTACCTTCTTTGTCTTTTCAGACTATCTCAAAGCAGCTGTTCGTTTGTCAGCCCTTCAAGGAGTACCAGTAACTT
ATGTCTTTACCCACGATTCGATTGCCGTTGGTGAAGATGGCCCTACTCATGAACCGATTGAACACTTGGCAGGTTTACGT
GCCACTCCTAATTTGGTTGTTTTTCGCCCAGCTGATGCACGCGAAACACAGGCAGCATGGCATTATGCTTTGACAAGCCA
AAACACACCAACAGCTCTTGTTTTGACACGTCAAAATCTTGATGTTGAAGCTGGTTCAAGCTTTACTTCAGTTGCTAAGG
GAGCTTATGTTACTTATGAAACAGATTCTGACTTTAATACCATTCTTTTGGCATCAGGTTCTGAAGTTAACTTAGCAGTC
AAAGCAGCTAAGGAATTGGAAGCACAAGGCGAAAAAGTACGTGTTGTTTCTGTTCCTTCTACAGAGCTCTTTGATGAGCA
ATCTGCTGCCTACAAAGAAGCTATTTTACCAAATTCAGTACGCCGTCGTGTAGCCATTGAAATGGCAGCCAGCCAACCAT
GGTATAAATATGTTGGTCTTGATGGTGCGGTTATCGGTATTGATAAATTTGGAGCATCAGCTCCTGCTGCTCAAGTCATT
GAAAATTATGGCTTTACAGTAGATAATGTGGTTAAAGTTGTTAAGGAACTGAAATAG

Protein sequence :
MSDLSVNAIRFLGVDAIEKSKSGHPGVVMGAAPMAYSLYTKHLRVNPSQPNWINRDRFVLSAGHGSMLLYALLHLSGFED
ISIDEIKNFRQWGSKTPGHPEYGHTVGVDVTTGPLGQGISMAVGLAQAERFLAAKYNREGYPIFDHYTYVIAGDGDFMEG
VSGEASSYAAKQNLDKLIVLYDSNDICLDGETNDAFTESVRARYDAYGWHTILVEDGNNIEAIGLAIEEAKAAGKPSLIE
IKTVIGYGAPTKGGTNAVHGAPLGAEEAAATRKALNWGYAPFEVPQEVYDDFKENVADRGEAAYDAWSNLVGEYRQAYPK
EAREVDAIIDGKDPVEIKEADFPVYENGFSQATRNSSQDAINAAADVLPNFLGGSADLAHSNMTYIKADGLQDADHPLNR
NIQFGVREFAMGTVLNGMALHGGLRVYGGTFFVFSDYLKAAVRLSALQGVPVTYVFTHDSIAVGEDGPTHEPIEHLAGLR
ATPNLVVFRPADARETQAAWHYALTSQNTPTALVLTRQNLDVEAGSSFTSVAKGAYVTYETDSDFNTILLASGSEVNLAV
KAAKELEAQGEKVRVVSVPSTELFDEQSAAYKEAILPNSVRRRVAIEMAASQPWYKYVGLDGAVIGIDKFGASAPAAQVI
ENYGFTVDNVVKVVKELK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 5e-155 50
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 1e-148 47