Gene Information

Name : metB (SMU_1675)
Accession : NP_722008.1
Strain : Streptococcus mutans UA159
Genome accession: NC_004350
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 1590478 - 1591572 bp
Length : 1095 bp
Strand : -
Note : Best Blastp Hit: pir||G64047 cystathionine gamma-lyase homolog - Haemophilus influenzae (strain Rd KW20) >gi|1573037|gb|AAC21764.1| (U32694) cystathionine gamma-synthase (metB) [Haemophilus influenzae Rd] 4.4.1.1 cystathionine gamma-lyase or cystathionine

DNA sequence :
ATGACTGAAGACTATAAATTAGATACTATTCTGGCACATGCAGGAATTAATACGGACAAGACAACAGGAGCTCTGACGGC
TCCTATTCATTTGTCAACAACTTATCAGCATCCTCAATTTGGTCAATCAACAGGTTTTGATTACACACGGACAAAAAATC
CTACCCGCACTGTTCTTGAAGAAACGCTGGCTAAAATTGAAAAGGCTAAATACGCTTTAGTAACATCGTCGGGTATGGCG
GCGCTTGTTTTGCTTTTTACTGGCTTTCCTATTGGGAGTAAGGTAGTTGCGGCGCGTGATTTATATGGTGGTTCTTTTCG
TTGGTTTAACGAACAGGAAAAAGCAGGAAGATTTTCTTTTGTTTACACCAATACAGAAACTGATATGATTGCTGCCATTT
CAGATGAGACCGATTATGTTTTTATCGAAACGCCAACCAATCCGCTCATGATTGAATTTGACATTAGTAAAGTTGCTCAA
GCAGCTCATAAGCATGGTGCCAAGGTCATTGTTGATAACACTTTTTACAGCCCTATTTATCAAAATCCGCTCGTTTTAGG
TGCTGATGTGGTTTTGCATTCAGCAACCAAGTATCTATCAGGTCATAATGATGTTCTTGCCGGTGTTTTAATGACCAGCG
ATCAAGAAATTTACGATAAGCTTTTTTATGACCAAAATACAACAGGTCCAACACTCTCGCCCTTAGATACTTATTTGCTG
ATGCGCGGTCTGAAAACACTTAAATTGCGTATGGAAAAAGCAACACAAAATGCTAAGACAGTTGTTGCTTATTTAGAAAA
ATCACCTGCTGTTAAAGAGGTACTTTATACAGGAAAAGGCGGAATGATTTCTTTTAAAGTTGTGGATGAAAAAAAAATTC
CGCAAATTCTCAATCATTTACAGCTGTTCACCTTTGCAGAAAGTTTAGGTGGCGTTGAAAGTTTAATTACTTATCCAGCG
ACACAGACACACTTGGATATACCGGAGGAAGTGCGTCATTCCTATGGTTTGACAGATGACTTACTGCGTCTGTCCATTGG
AATTGAAGATGCGGAAGACTTGATTGATGATTTAAAAGCTGCTTTAGAAGCTTAA

Protein sequence :
MTEDYKLDTILAHAGINTDKTTGALTAPIHLSTTYQHPQFGQSTGFDYTRTKNPTRTVLEETLAKIEKAKYALVTSSGMA
ALVLLFTGFPIGSKVVAARDLYGGSFRWFNEQEKAGRFSFVYTNTETDMIAAISDETDYVFIETPTNPLMIEFDISKVAQ
AAHKHGAKVIVDNTFYSPIYQNPLVLGADVVLHSATKYLSGHNDVLAGVLMTSDQEIYDKLFYDQNTTGPTLSPLDTYLL
MRGLKTLKLRMEKATQNAKTVVAYLEKSPAVKEVLYTGKGGMISFKVVDEKKIPQILNHLQLFTFAESLGGVESLITYPA
TQTHLDIPEEVRHSYGLTDDLLRLSIGIEDAEDLIDDLKAALEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-61 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-62 43